Carles Jordà i Fages (1883-1935). Dirigent d’Acció Catalana i de la Unió Sindical Agrària

Carles Jordà i Fages neix a Figueres el 1883 i mor a Pont de Molins el 1935. És l’hereu d’una família d’hisendats que aviat diversificarà les seves inversions, de manera decidida, en el negoci bancari, la qual cosa permetrà que ell i les seves germanes es traslladin a estudiar a Barcelona. Estudiarà enginyeria i entrarà en contacte amb els nuclis catalanistes de la Lliga que el portaran a ser elegit per a càrrecs polítics a la Mancomunitat de Catalunya i a l’Ajuntament de Barcelona, on arribarà a ser alcalde accidental. Unes inversions amb mals resultats truncaran la seva vida barcelonina i el 1921 retornarà a l’Empordà. On manté la seva presència política i serà un dels fundadors d’Acció Catalana. Per la seva afiliació política, durant la dictadura de Primo de Rivera serà perseguit i exiliat a Casp. De retorn a l’Empordà, impulsa el cooperativisme agrari. Amb la II República mantindrà la seva adscripció política, però, sobretot, accentuarà la seva faceta de dirigent agrari des de la Unió Sindical Agrària, que se situarà en una difícil aposta, entre la patronal agrària i el sindicalisme rabassaire, tot buscant fórmules de concòrdia i entesa en moments de radicalització. Morirà en plena maduresa el 1935. La seva memòria es perdrà durant el franquisme i la democràcia restaurada.Carles Jordà I Fages was born in Figueres in 1883 and died in Pont de Molins in 1935. He was the heir of a family of landowners who early on determined to diversify their investments in banking businesses, among others. This allowed him and his sisters to move to Barcelona for their studies. He studied engineering and came into contact with the Catalan centres of the Lliga which led to his election to political offices during theMancomunitat de Catalonia and at the city council of Barcelona, where he became acting mayor. Some bad investments led to the end of his residence in Barcelona and he returned to the Empordà in 1921 where he maintained his political presence and became one of the founders of Acció Catalana. During the Primo de Rivera dictatorship he was persecuted for his political alliances and exiled to Casp. Upon return to the Empordà, he promoted agrarian cooperatives. With the Second Republic, he maintained his political subscription but especially accentuated his role as agrarian leader with the Unió Sindical Agrària, which, with a difficult commitment, acted between the agrarian landowners’ union and workers' syndicalism by trying to find peaceful ways and understanding in times of radicalization. He died at a prime age in 1935 while developing his role as mediator. His legacy was forgotten during the Franco regime and the restored democracy

Relació i estudi general dels plets en els que es veiè involucrada una família pagesa de la Catalunya vella, al regnat de Carles III

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Scrobipalpa Ocellatella (Boyd) y su comportamiento sexual lucha integrada contra la plaga (Lep. Gelechiidae)

En aquest treball es dóna informació sobre l'ecologia i comportament de Scrobipalpa ocellatella (Boyd.), que s'alimenta de bledes, remolatxa sucrera i altres plantes del gènere Beta. Es descriu el cicle biològic a Catalunya, prop de Barcelona. Hom ha estudiat, durant els anys 1979/80/81/82/83, a diversos indrets del país utilitzant feromones, demostrant que la proporció 90/10 (E3DDA/Z3DDA) ha estat la més efectiva com a component dels programes de lluita integrada.Information is provided on the bioecology and behaviour of the moth Scrobipalpa ocellatella (Boyd), which develops on leaf beet, sugar beet and other plants of the genus Beta in Iberian peninsula. The life cycle is given in Catalonian, near Barcelone. A field study carried out during the years 1979/80/81/82/83 in various parts of the country using sex pheromone of this species, the (E)-3 Dodecenyl acetate (E3DDA), showed that the proportion 90/10 (E3DDA/Z3DDA) was the more effective attractant as a component of integrated pest control programmes

Sobre la presència de GortynaXanthenes (Gemar) a Catalunya (Lep. Noctuidae)

Els autors han estudiat el lepidòpter noctAia Gortyna xanthenes (Germar), que es troba a les comarques del Baix Llobregat i Baix ---Ebre, atacant carxofa (Cynara scolymus L.). Aquesta espècie és la plaga més important de l'esmentat conreu. S'indiquen algunes característiques de la morfologia, ecologia i comportament en el desenvolupament--- del lepidòpter a Catalunya. Es discuteix a més, la possibilitat d'emprar lluita integrada.The authors have studied the artichoke moth Gortyna xanthenes (Germar), (Lep. Noctuidaé), which is found in "Baix Llobregat" and ---"Baix Ebre" regions, attaking globe artichoke. This species is a major pest of this plant. The morphological, bioecological and behavioural --- conditions of development are indicated, in Catalonia. The possibility of integrated pest management are discuted.Los autores han estudiado el lepidóptero noctuido Gortyna Xanthenes (Germar), el cual se encuentra en las comarcas del "Baix Llobregat" y "Baix Ebre", atacando alcachofas (Cynara scolymus L.). El lepidóptero constituye la plaga más importante para dicho cultivo. Se dan algunas características morfológicas, ecológicas y de comportamiento en el desarrollo de ésta especie en Cataluña. Se discute además, la posibilidad de emplear la lucha integrada

Els diputats altempordanesos de la Mancomunitat. Apunts biogràfics

L’article és un recull de les biografies dels diputats provincials escollits en el districte de Figueres i que formaren part de l’Assemblea de la Mancomunitat de Catalunya entre  1914 i 1925.This article is a collection of biographies of provincial deputees chosen in the district of Figueres who belonged to the Assembly of the Mancomunitat de Catalunya between 1914-1925

Hèrnia discal, una malaltia infecciosa?

Estudi prospectiu de casos-controls on s'intenta determinar el paper de P.acnes en l'etiopatogènia de la hèrnia discal. Es van analitzar a microbiologia i anatomia patològica les mostres de teixit de disc intervertebral extretes en cirurgia d'hèrnia discal en 40 pacients, i en 27 pacients intervinguts per altres patologies de columna vertebral. Els nostres resultats recolzen la hipòtesi de que la troballa de P.acnes en el disc és un contaminant, ja que no hem trobat evidència de que el procés inflamatori associat a l'hèrnia discal i la ciatàlgia tingui una etiopatogènia infecciosa

P53 in Penile Squamous Cell Carcinoma : A Pattern-Based Immunohistochemical Framework with Molecular Correlation

Penile squamous cell carcinomas harbouring mutations of TP53 have an increased risk of lymph node metastases and an impaired prognosis, but the mutational analysis of the TP53 gene is not available in many pathology laboratories. Although p53 immunohistochemistry (IHC) has been proposed as an alternative to the molecular analysis, the current method of evaluation of p53 IHC has many inaccuracies. The aim of our study was to determine, in a series of 40 penile tumours, if a recently described pattern-based framework of p53 IHC evaluation correlates better than the classical method with the TP53 mutational status. Our results show that the new method has a very good correlation with TP53 mutations (95% sensitivity; 92% specificity), higher than that of the classical method, and can be considered as a reliable surrogate of the TP53 mutational status. This new framework can help clinicians to better define risk groups and refine treatment strategies. p53 immunohistochemistry (IHC) has been proposed as a surrogate for TP53 mutations in penile squamous cell carcinomas (PSCC). We aimed to evaluate the performance of a pattern-based evaluation of p53 IHC in PSCC. Human papilloma virus (HPV) DNA testing, p16 and p53 IHC, and whole exome sequencing were performed in a series of 40 PSCC. p53 IHC was evaluated following a pattern-based framework and conventional p53 IHC evaluation. Out of 40 PSCC, 12 (30.0%) were HPV-associated, and 28 (70.0%) were HPV-independent. The agreement between the p53 IHC pattern-based evaluation and TP53 mutational status was almost perfect (k = 0.85). The sensitivity and accuracy of the pattern-based framework for identifying TP53 mutations were 95.5% and 92.5%, respectively, which were higher than the values of conventional p53 IHC interpretation (54.5% and 70.0%, respectively), whereas the specificity was the same (88.9%). In conclusions, the pattern-based framework improves the accuracy of detecting TP53 mutations in PSCC compared to the classical p53 IHC evaluation

Clustering COVID-19 ARDS patients through the first days of ICU admission. An analysis of the CIBERESUCICOVID Cohort

Background Acute respiratory distress syndrome (ARDS) can be classified into sub-phenotypes according to different inflammatory/clinical status. Prognostic enrichment was achieved by grouping patients into hypoinflammatory or hyperinflammatory sub-phenotypes, even though the time of analysis may change the classification according to treatment response or disease evolution. We aimed to evaluate when patients can be clustered in more than 1 group, and how they may change the clustering of patients using data of baseline or day 3, and the prognosis of patients according to their evolution by changing or not the cluster.Methods Multicenter, observational prospective, and retrospective study of patients admitted due to ARDS related to COVID-19 infection in Spain. Patients were grouped according to a clustering mixed-type data algorithm (k-prototypes) using continuous and categorical readily available variables at baseline and day 3.Results Of 6205 patients, 3743 (60%) were included in the study. According to silhouette analysis, patients were grouped in two clusters. At baseline, 1402 (37%) patients were included in cluster 1 and 2341(63%) in cluster 2. On day 3, 1557(42%) patients were included in cluster 1 and 2086 (57%) in cluster 2. The patients included in cluster 2 were older and more frequently hypertensive and had a higher prevalence of shock, organ dysfunction, inflammatory biomarkers, and worst respiratory indexes at both time points. The 90-day mortality was higher in cluster 2 at both clustering processes (43.8% [n = 1025] versus 27.3% [n = 383] at baseline, and 49% [n = 1023] versus 20.6% [n = 321] on day 3). Four hundred and fifty-eight (33%) patients clustered in the first group were clustered in the second group on day 3. In contrast, 638 (27%) patients clustered in the second group were clustered in the first group on day 3.Conclusions During the first days, patients can be clustered into two groups and the process of clustering patients may change as they continue to evolve. This means that despite a vast majority of patients remaining in the same cluster, a minority reaching 33% of patients analyzed may be re-categorized into different clusters based on their progress. Such changes can significantly impact their prognosis