Assessing the test-retest reliability of the social value orientation slider measure

Decades of research show that (i) social value orientation (SVO) is related to important behavioral outcomes such as cooperation and charitable giving, and (ii) individuals differ in terms of SVO. A prominent scale to measure SVO is the social value orientation slider measure (SVOSM). The central premise is that SVOSM captures a stable trait. But it is unknown how reliable the SVOSM is over repeated measurements more than one week apart. To fill this knowledge gap, we followed a sample of N = 495 over 6 months with monthly SVO measurements. We find that continuous SVO scores are similarly distributed (Anderson-Darling k-sample p = 0.57) and highly correlated (r ≥ 0.66) across waves. The intra-class correlation coefficient of 0.78 attests to a high test-retest reliability. Using multilevel modeling and multiple visualizations, we furthermore find that one’s prior SVO score is highly indicative of SVO in future waves, suggesting that the slider measure consistently captures one’s SVO. Our analyses validate the slider measure as a reliable SVO scale

A Bad Barrel Spoils a Good Apple:How Uncertainty and Networks Affect Whether Matching Rules Can Foster Cooperation

Meritocratic matching solves the problem of cooperation by ensuring that only prosocial agents group together while excluding proselfs who are less inclined to cooperate. However, matching is less effective when estimations of individual merit rely on group-level outcomes. Prosocials in uncooperative groups are unable to change the nature of the group and are themselves forced to defect to avoid exploitation. They are then indistinguishable from proselfs, preventing them from accessing cooperative groups. We investigate informal social networks as a potential solution. Interactions in dyadic network relations provide signals of individual cooperativeness which are easier to interpret. Network relations can thus help prosocials to escape from uncooperative groups. To test our intuitions, we develop an ABM modeling cooperative behavior based on a stochastic learning model with adaptive thresholds. We investigate both randomly and homophilously formed networks. We find that homophilous networks create conditions under which meritocratic matching can function as intended. Simulation experiments identify two underlying reasons. First, dyadic network interactions in homophilous networks differentiate more between prosocials and proselfs. Second, homophilous networks create groups of prosocial agents who are aware of each other’s behavior. The stronger this prosociality segregation is, the more easily prosocials cooperate in the group context. Further analyses also highlight a downside of homophilous networks. When prosocials successfully escape from uncooperative groups, non-cooperatives have fewer encounters with prosocials, diminishing their chances to learn to cooperate through those encounters

The role of analytical chemistry in exposure science: Focus on the aquatic environment

Exposure science, in its broadest sense, studies the interactions between stressors (chemical, biological, and physical agents) and receptors (e.g. humans and other living organisms, and non-living items like buildings), together with the associated pathways and processes potentially leading to negative effects on human health and the environment. The aquatic environment may contain thousands of compounds, many of them still unknown, that can pose a risk to ecosystems and human health. Due to the unquestionable importance of the aquatic environment, one of the main challenges in the field of exposure science is the comprehensive characterization and evaluation of complex environmental mixtures beyond the classical/priority contaminants to new emerging contaminants. The role of advanced analytical chemistry to identify and quantify potential chemical risks, that might cause adverse effects to the aquatic environment, is essential. In this paper, we present the strategies and tools that analytical chemistry has nowadays, focused on chromatography hyphenated to (high-resolution) mass spectrometry because of its relevance in this field. Key issues, such as the application of effect direct analysis to reduce the complexity of the sample, the investigation of the huge number of transformation/degradation products that may be present in the aquatic environment, the analysis of urban wastewater as a source of valuable information on our lifestyle and substances we consumed and/or are exposed to, or the monitoring of drinking water, are discussed in this article. The trends and perspectives for the next few years are also highlighted, when it is expected that new developments and tools will allow a better knowledge of chemical composition in the aquatic environment. This will help regulatory authorities to protect water bodies and to advance towards improved regulations that enable practical and efficient abatements for environmental and public health protection

Urinary Calcium Excretion and Risk of Chronic Kidney Disease in the General Population

High urinary calcium excretion (UCaE) has been shown to lead to accelerated renal function decline in individuals with renal tubular diseases. It is not known whether this association also exists in the general population. Therefore, we investigated whether high UCaE is associated with risk of developing chronic kidney disease (CKD) in community-dwelling subjects. Methods: Urine samples of 5491 subjects who were free of CKD at baseline and participated in the Prevention of Renal and Vascular End-Stage Disease study (a prospective, observational, general population-based cohort of Dutch men and women aged 28–75 years) were examined for UCaE. UCa concentration was measured in two 24-hour urine samples at baseline (1997–1998) by indirect potentiometry. UCaE was treated as a continuous variable and a categorical variable grouped according to sex-specific quintiles for UCaE. UCaE was compared with de novo development of estimated glomerular filtration rate <60 ml/min per 1.73 m2 and/or albuminuria >30 mg/24 h. Results: Baseline median UCaE was 4.13 mmol/24 h for men and 3.52 mmol/24 h for women. During a median follow-up of 10.3 years, 899 subjects developed CKD. After multivariable adjustment, every 1 mmol/24 h higher baseline UCaE was associated with a 6% lower risk for incident CKD during follow-up (hazard ratio: 0.94 [0.88–0.99], P = 0.02). The association was shown to be significantly nonlinear, with highest risk of CKD in the lowest quintile for UCaE (hazard ratio: 1.28 [0.97–1.68], P = 0.09). There was no association between UCaE and mortality or cardiovascular health during follow-up, suggesting that this association was not a reflection of poor nutritional intake due to bad health. Discussion: These findings indicate that high UCaE does not increase risk of CKD, but rather that low UCaE may be harmful

CUBN as a Novel Locus for End-Stage Renal Disease: Insights from Renal Transplantation

Chronic kidney disease (CKD) is a complex disorder. As genome-wide association studies identified cubilin gene CUBN as a locus for albuminuria, and urinary protein loss is a risk factor for progressive CKD, we tested the hypothesis that common genetic variants in CUBN are associated with end-stage renal disease (ESRD) and proteinuria. First, a total of 1142 patients with ESRD, admitted for renal transplantation, and 1186 donors were genotyped for SNPs rs7918972 and rs1801239 (case-control study). The rs7918972 minor allele frequency (MAF) was higher in ESRD patients comparing to kidney donors, implicating an increased risk for ESRD (OR 1.39, p = 0.0004) in native kidneys. Second, after transplantation recipients were followed for 5.8 [3.8–9.2] years (longitudinal study) documenting ESRD in transplanted kidneys – graft failure (GF). During post-transplant follow-up 92 (9.6%) cases of death-censored GF occurred. Donor rs7918972 MAF, representing genotype of the transplanted kidney, was 16.3% in GF vs 10.7% in cases with functioning graft. Consistently, a multivariate Cox regression analysis showed that donor rs7918972 is a predictor of GF, although statistical significance was not reached (HR 1.53, p = 0.055). There was no association of recipient rs7918972 with GF. Rs1801239 was not associated with ESRD or GF. In line with an association with the outcome, donor rs7918972 was associated with elevated proteinuria levels cross-sectionally at 1 year after transplantation. Thus, we identified CUBN rs7918972 as a novel risk variant for renal function loss in two independent settings: ESRD in native kidneys and GF in transplanted kidneys

Increase in soil erosion after agricultural intensification: evidence from a lowland basin in France

International audienceChanges in agricultural practices impact sediment transfer in catchments and rivers. Long term archives of sediment deposits in agricultural plains of northwestern Europe are rarely available, however, for reconstructing and quantifying erosion and sedimentation rates for the second half of the 20th century. In this context, a multi-parameter analysis was conducted on sedimentary deposits accumulated in a pond created in the 11th century and draining a 24 km2 cultivated catchment in western France. This catchment is representative of cultivated and drained lowland environments where agriculture has intensified during the last 60 years.High resolution seismic profiles and surface sediment samples (n = 74) were used to guide the collection of cores (n = 3) representative of the sequence of sediment accumulated in the pond. The cores were analysed to quantify and characterize the evolution of sediment dynamics in the pond.The first land consolidation period (1954-1960) was characterized by a dominance of allochtonous material input to the pond. This input represents an erosion of 1900 to 2300 t.km−2.yr−1 originating from the catchment. Then, between 1970-1990, the terrigenous input decreased progressively and tended to stabilize. Eutrophication and associated primary production increased in the pond. These processes generated the majority of material accumulated in the pond during this period. Further land consolidation programs conducted in 1992 generated a new increase in soil erosion and sediment input to the reservoir. For the last 10 years, terrigenous input to the pond corresponds to a catchment-wide erosion rate between 90 and 102 t.km−2.yr−1. While a strong decrease is observed, it still represents a 60-fold increase of the sediment flux compared to the pre-intensification period. These large temporal variations of sedimentation rates over a few decades underline the dynamics of sediment transfer and raise questions about the sustainability of soil resources in lowland temperate environments