General and clinical epidemiology at square two: A new educational series for the renal physician

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Urotensin in ESRD: Not so surprising

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Homocysteine and risk in end-stage renal disease: a matter of context

Like blood pressure and cholesterol, hoocysteine shows a paradoxical inverse relationship with cardiovascular complications in end-stage renal disease (ESRD). A paper by Ducloux et al. in this issue adds perhaps decisive evidence on malnutrition-hypoalbuminemia as the main factor explaining the counterintuitive association between homocysteine and clinical outcome reported in previous studies

Arthroscopic patterns of the poster-medial aspect of the knee joint: classification of the gastrocnemius-semimembranosus gateway and its relationship with Baker's cyst

Background The gastrocnemius-semimembranosus bursa may communicate with the knee joint. The arthroscopic anatomy of the posteromedial aspect varies depending on the angle of the oblique popliteal ligament, the level at which it crosses the medial gastrocnemius tendon, and its relationship with the capsular joint and synovia. The aim of this paper is to identify possible patterns, and to evaluate their characteristics and their relationship with Baker’s cyst. Methods data archived from 185 consecutive arthroscopies were evaluated; an anatomic description and classification was carried out; the percentages of association with BC and the associated pathologies were reported. Results The different anatomies were classified into six groups based on the relationship above the medial gastrocnemius tendon, the capsular joint and synovia. The prevalence of Baker’s cyst was 28.3%. The main associated intra-articular pathological condition was the contemporary presence of a meniscal tear and chondropathy. Conclusion Exploration of the posterior aspect of the knee must be performed routinely. Knowing the possible anatomy patterns of the posteromedial arthroscopic aspect of the knee joint could help to identify the cyst and its gateway, thus facilitating its treatment

NTT infrared imaging of star cluster candidates towards the central parts of the Galaxy

We address the issue whether the central parts of the Galaxy harbour young clusters other than Arches, Quintuplet and the Nuclear Young Cluster. A large sample of centrally projected cluster candidates has been recently identified from the 2MASS J, H and Ks Atlas. We provide a catalogue of higher angular resolution and deeper images for 57 2MASS cluster candidates, obtained with the near-IR camera SOFI at the ESO NTT telescope. We classify 10 objects as star clusters, some of them deeply embedded in gas and/or dust clouds. Three other objects are probably star clusters, although the presence of dust in the field does not exclude the possibility of their being field stars seen through low-absorption regions. Eleven objects are concentrations of stars in areas of little or no gas, and are classified as dissolving cluster candidates. Finally, 31 objects turned out to be the blend of a few bright stars, not resolved as such in the low resolution 2MASS images. By combining the above results with other known objects we provide an updated sample of 42 embedded clusters and candidates projected within 7 degrees. As a first step we study Object 11 of Dutra & Bica (2000) projected at approximately 1 degree from the nucleus. We present H and Ks photometry and study the colour-magnitude diagram and luminosity function. Object 11 appears to be a less massive cluster than Arches or Quintuplet, and it is located at a distance from the Sun d=8 kpc, with a visual absorption Av=15.Comment: accepted to A&A, 9 pages, 10 figure

Lung congestion as a hidden threat in end-stage kidney disease: a call to action

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Mass accretion rates from multi-band photometry in the Carina Nebula: the case of Trumpler 14

We present a study of the mass accretion rates of pre-Main Sequence (PMS) stars in the cluster Trumpler 14 (Tr14) in the Carina Nebula. Using optical multi-band photometry we were able to identify 356 PMS stars showing H-alpha excess emission with equivalent width EW(H-alpha)>20\AA. We interpret this observational feature as indication that these objects are still actively accreting gas from their circumstellar medium. From a comparison of the HR diagram with PMS evolutionary models we derive ages and masses of the PMS stars. We find that most of the PMS objects are younger than 10 Myr with a median age of ~3 Myr. Surprisingly, we also find that ~20% of the mass accreting objects are older than 10 Myr. For each PMS star in Trumpler 14 we determine the mass accretion rate ($\dot{M}_{acc}$) and discuss its dependence on mass and age. We finally combine the optical photometry with near-IR observations to build the spectral energy distribution (SED) for each PMS star in Tr14. The analysis of the SEDs suggests the presence of transitional discs in which a large amount of gas is still present and sustains accretion onto the PMS object at ages older than 10 Myr. Our results, discussed in light of recent recent discoveries with Herschel of transitional discs containing a massive gas component around the relatively old PSM stars TW Hydrae, 49 Ceti, and HD 95086, support a new scenario in which old and evolved debris discs still host a significant amount of gas.Comment: 12 pages, 13 figures, accepted for publication on A&