531 research outputs found

    Ferromagnetism of a Repulsive Atomic Fermi Gas in an Optical Lattice: a Quantum Monte Carlo Study

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    Using continuous-space quantum Monte Carlo methods we investigate the zero-temperature ferromagnetic behavior of a two-component repulsive Fermi gas under the influence of periodic potentials that describe the effect of a simple-cubic optical lattice. Simulations are performed with balanced and with imbalanced components, including the case of a single impurity immersed in a polarized Fermi sea (repulsive polaron). For an intermediate density below half filling, we locate the transitions between the paramagnetic, and the partially and the fully ferromagnetic phases. As the intensity of the optical lattice increases, the ferromagnetic instability takes place at weaker interactions, indicating a possible route to observe ferromagnetism in experiments performed with ultracold atoms. We compare our findings with previous predictions based on the standard computational method used in material science, namely density functional theory, and with results based on tight-binding models.Comment: Published version with Supplemental Material. Added comparison with Hubbard model result

    Simple Modifications of Branched PEI Lead to Highly Efficient siRNA Carriers with Low Toxicity

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    Polymer carriers like PEI which proved their efficiency in DNA delivery were found to be far less effective for the applications with siRNA. In the current study, we generated a number of nontoxic derivates of branched PEI through modification of amines by ethyl acrylate, acetylation of primary amines, or introduction of negatively charged propionic acid or succinic acid groups to the polymer structure. The resulting products showed high efficiency in siRNA-mediated knockdown of target gene. In particular, succinylation of branched PEI resulted in up to 10-fold lower polymer toxicity in comparison to unmodified PEI. Formulations of siRNA with succinylated PEI were able to induce remarkable knockdown (80% relative to untreated cells) of target luciferase gene at the lowest tested siRNA concentration of 50 nM in Neuro2ALuc cells. The polyplex stability assay revealed that the efficiency of formulations which are stable in physiological saline is independent of the affinity of siRNA to the polymer chain. The improved properties of modified PEI as siRNA carrier are largely a consequence of the lower polymer toxicity. In order to achieve significant knockdown of target gene, the PEI-based polymer has to be applied at higher concentrations, required most probably for sufficient accumulation and proton sponge effects in endosomes. Unmodified PEI is highly toxic at such polymer concentrations. In contrast, the far less toxic modified analogues can be applied in concentrations required for the knockdown of target genes without side effects

    Density functional theory versus quantum Monte Carlo simulations of Fermi gases in the optical-lattice arena

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    We benchmark the ground state energies and the density profiles of atomic repulsive Fermi gases in optical lattices computed via Density Functional Theory (DFT) against the results of diffusion Monte Carlo (DMC) simulations. The main focus is on a half-filled one-dimensional optical lattices, for which the DMC simulations performed within the fixed-node approach provide unbiased results. This allows us to demonstrate that the local spin-density approximation (LSDA) to the exchange-correlation functional of DFT is very accurate in the weak and intermediate interactions regime, and also to underline its limitations close to the strongly-interacting Tonks-Girardeau limit and in very deep optical lattices. We also consider a three dimensional optical lattice at quarter filling, showing also in this case the high accuracy of the LSDA in the moderate interaction regime. The one-dimensional data provided in this study may represent a useful benchmark to further develop DFT methods beyond the LSDA and they will hopefully motivate experimental studies to accurately measure the equation of state of Fermi gases in higher-dimensional geometries.Comment: 8 pages, 7 figures, plus supplemental material (1 page). Typos correcte

    Имитатор закладного устройства для нелинейного радиолокатора

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    Запропонована навантажена на нелінійний елемент плоска спіральна антена, як єдиний імітатор закладного пристрою для нелінійного радіолокатора. Дослідження підтвердили ідентифікацію закладного пристрою, як електронного об’єкту, при впливі завад.Is offered, as the uniform simulator of the mortgage device for nonlinear radio locator, flat spiral aerial loaded on a nonlinear element. The researches have confirmed identification of the mortgage device as electronic object, in conditions of influence of handicaps.Предложена, в качестве единого имитатора закладного устройства для нелинейного радиолокатора, плоская спиральная антенна, нагруженная на нелинейный элемент. Исследования подтвердили идентификацию закладного устройства, как электронного объекта, в условиях влияния помех

    Physics of the Muon Spectrometer of the ALICE Experiment

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    The main goal of the Muon spectrometer of the ALICE experiment at LHC is the measurement of heavy quark production in p+p, p+A and A+A collisions at LHC energies, via the muonic channel. Physics motivations and expected performances have been presented in this talk.Comment: 10 pages and 4 figures. Talk presented in the ICPAQGP Conference, February 8-12, 2005, Salt Lake City, Kolkata, India. Web page of the conference : http://www.veccal.ernet.in/~icpaqgp
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