884 research outputs found
Laparoscopic Transient Uterine Artery Occlusion and Myomectomy for Symptomatic Uterine Myoma as an Alternative to Hysterectomy
Objective: To compare the clinical outcomes of laparoscopic transient uterine artery ligation plus myomectomy (LTUAL) to simple laparoscopic myomectomy (LM) for symptomatic myomas
Fast Neighbor Discovery for Wireless Ad Hoc Network with Successive Interference Cancellation
Neighbor discovery (ND) is a key step in wireless ad hoc network, which
directly affects the efficiency of wireless networking. Improving the speed of
ND has always been the goal of ND algorithms. The classical ND algorithms lose
packets due to the collision of multiple packets, which greatly affects the
speed of the ND algorithms. Traditional methods detect packet collision and
implement retransmission when encountering packet loss. However, they does not
solve the packet collision problem and the performance improvement of ND
algorithms is limited. In this paper, the successive interference cancellation
(SIC) technology is introduced into the ND algorithms to unpack multiple
collision packets by distinguishing multiple packets in the power domain.
Besides, the multi-packet reception (MPR) is further applied to reduce the
probability of packet collision by distinguishing multiple received packets,
thus further improving the speed of ND algorithms. Six ND algorithms, namely
completely random algorithm (CRA), CRA based on SIC (CRA-SIC), CRA based on SIC
and MPR (CRA-SIC-MPR), scan-based algorithm (SBA), SBA based on SIC (SBA-SIC),
and SBA based on SIC and MPR (SBA-SIC-MPR), are theoretically analyzed and
verified by simulation. The simulation results show that SIC and MPR reduce the
ND time of SBA by 69.02% and CRA by 66.03% averagely.Comment: 16 pages, 16 figure
Comparative Proteomic Analysis of Panax ginseng C. A. Meyer Ă Panax quinquefolius L. Leaves and Parental Lines
Heterosis refers to the superior performance of heterozygous F1 hybrid plants with respect to those of their genetically distinct parents. Despite its wide use in crops, heterosis is seldom applied in the Panax genus, and its molecular basis remains unclear. Thus, this study is aimed to obtain hybrid F1s and identify the proteins associated with heterosis. Hybrid F1 plants and parental inbred lines were obtained using the embryo rescue technique, and the proteomes of their leaves were analyzed using twoâdimensional gel electrophoresis. A total of 236 differentially expressed proteins were found, among which 84 nonadditive proteins indicated a heterosis pattern in the hybrid. Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes analysis revealed that photosynthesis, carbohydrate metabolism, and protein and amino acid synthesis were the most abundant classes of nonadditive proteins. Of the proteins in these categories, 10, 6, and 4 proteins, respectively, showed above high parent expression in the hybrid leaves. These results imply that the increment in photosynthetic capacity, carbohydrate decomposition, and nitrogen fixation might be related to the heterosis of the hybrid biomass and ginsenoside production in the hybrid leaves. This study could provide a basis for hybrid breeding of the Panax genus
Rapid fabrication of silver nanoparticle/polydopamine functionalized polyester fibers
In this paper, silver nanoparticles functionalized poly(ethylene terephthalate) (PET) fibers with antimicrobial activity, electrical conductivity and good coating stability are reported. Firstly, silver plated PET fibers were fabricated by rapid polydopamine (PDA) modification followed by electroless plating. Secondly, the surface morphologies and compositions of PDA modified and silver coated PET fibers were characterized by employing scanning electron microscopy, atomic force microscopy, X-ray diffraction and energy dispersive spectrometry. Finally, the antimicrobial properties and electrical conductivity of the silver plated PET fibers were investigated. The results showed that the silver coated PET fibers exhibited excellent antimicrobial activity to both Escherichia coli and Staphylococcus aureus (with an antimicrobial efficiency of 100 and 99.99%, respectively), and that the antimicrobial activity was well maintained after washing. The silver coated PET fibers showed electrical resistance of 0.76âΩ per 1âcm, indicating good conductivity. It was also demonstrated that the silver layer that formed had good mechanical durability, as indicated by conductivity measurements during tensile loading and observation of the surface morphology of the fibers under various modes of deformation
Noncanonical Wnt signaling promotes apoptosis in thymocyte development
The WntâÎČ-catenin signaling pathway has been shown to govern T cell development by regulating the growth and survival of progenitor T cells and immature thymocytes. We explore the role of noncanonical, WntâCa2+ signaling in fetal T cell development by analyzing mice deficient for Wnt5a. Our findings reveal that Wnt5a produced in the thymic stromal epithelium does not alter the development of progenitor thymocytes, but regulates the survival of αÎČ lineage thymocytes. Loss of Wnt5a down-regulates Bax expression, promotes Bcl-2 expression, and inhibits apoptosis of CD4+CD8+ thymocytes, whereas exogenous Wnt5a increases apoptosis of fetal thymocytes in culture. Furthermore, Wnt5a overexpression increases apoptosis in T cells in vitro and increases protein kinase C (PKC) and calmodulin-dependent kinase II (CamKII) activity while inhibiting ÎČ-catenin expression and activity. Conversely, Wnt5a deficiency results in the inhibition of PKC activation, decreased CamKII activity, and elevation of ÎČ-catenin amounts in thymocytes. These results indicate that Wnt5a induction of the noncanonical WntâCa2+ pathway alters canonical Wnt signaling and is critical for normal T cell development
5G PRS-Based Sensing: A Sensing Reference Signal Approach for Joint Sensing and Communication System
The emerging joint sensing and communication (JSC) technology is expected to
support new applications and services, such as autonomous driving and extended
reality (XR), in the future wireless communication systems. Pilot (or
reference) signals in wireless communications usually have good passive
detection performance, strong anti-noise capability and good auto-correlation
characteristics, hence they bear the potential for applying in radar sensing.
In this paper, we investigate how to apply the positioning reference signal
(PRS) of the 5th generation (5G) mobile communications in radar sensing. This
approach has the unique benefit of compatibility with the most advanced mobile
communication system available so far. Thus, the PRS can be regarded as a
sensing reference signal to simultaneously realize the functions of radar
sensing, communication and positioning in a convenient manner. Firstly, we
propose a PRS based radar sensing scheme and analyze its range and velocity
estimation performance, based on which we propose a method that improves the
accuracy of velocity estimation by using multiple frames. Furthermore, the
Cramer-Rao lower bound (CRLB) of the range and velocity estimation for PRS
based radar sensing and the CRLB of the range estimation for PRS based
positioning are derived. Our analysis and simulation results demonstrate the
feasibility and superiority of PRS over other pilot signals in radar sensing.
Finally, some suggestions for the future 5G-Advanced and 6th generation (6G)
frame structure design containing the sensing reference signal are derived
based on our study
Aligning Large Multimodal Models with Factually Augmented RLHF
Large Multimodal Models (LMM) are built across modalities and the
misalignment between two modalities can result in "hallucination", generating
textual outputs that are not grounded by the multimodal information in context.
To address the multimodal misalignment issue, we adapt the Reinforcement
Learning from Human Feedback (RLHF) from the text domain to the task of
vision-language alignment, where human annotators are asked to compare two
responses and pinpoint the more hallucinated one, and the vision-language model
is trained to maximize the simulated human rewards. We propose a new alignment
algorithm called Factually Augmented RLHF that augments the reward model with
additional factual information such as image captions and ground-truth
multi-choice options, which alleviates the reward hacking phenomenon in RLHF
and further improves the performance. We also enhance the GPT-4-generated
training data (for vision instruction tuning) with previously available
human-written image-text pairs to improve the general capabilities of our
model. To evaluate the proposed approach in real-world scenarios, we develop a
new evaluation benchmark MMHAL-BENCH with a special focus on penalizing
hallucinations. As the first LMM trained with RLHF, our approach achieves
remarkable improvement on the LLaVA-Bench dataset with the 94% performance
level of the text-only GPT-4 (while previous best methods can only achieve the
87% level), and an improvement by 60% on MMHAL-BENCH over other baselines. We
opensource our code, model, data at https://llava-rlhf.github.io.Comment: Preprin
Preparation and characterization of a novel triple composite scaffold containing silk fibroin, chitosan, extracellular matrix and the mechanism of Akt/FoxO signaling pathway in colonic cancer cells cultured in 3D
This work examined the physical and chemical properties and biocompatibility in vivo and in vitro of a unique triple composite scaffold incorporating silk fibroin, chitosan, and extracellular matrix. The materials were blended, cross-linked, and freeze-dried to create a composite scaffold of silk fibroin/chitosan/colon extracellular matrix (SF/CTS/CEM) with varying CEM contents. The SF/CTS/CEM (1:1:1) scaffold demonstrated the preferable shape, outstanding porosity, favorable connectivity, good moisture absorption, and acceptable and controlled swelling and degradation properties. Additionally, HCT-116 cells cultivated with SF/CTS/CEM (1:1:1) showed excellent proliferation capacity, cell malignancy, and delayed apoptosis, according to the in vitro cytocompatibility examination. We also examined the PI3K/PDK1/Akt/FoxO signaling pathway and discovered that cell culture using a SF/CTS/CEM (1:1:1) scaffold may prevent cell death by phosphorylating Akt and suppressing FoxO expression. Our findings demonstrate the potential of the SF/CTS/CEM (1:1:1) scaffold as an experimental model for colonic cancer cell culture and for replicating the three-dimensional in vivo cell growth environment
Study of
We present an analysis of the decay based
on data collected by the BESIII experiment at the resonance. Using
a nearly background-free sample of 18262 events, we measure the branching
fraction . For GeV/ the partial branching fraction is
. A partial wave analysis shows that the dominant
component is accompanied by an \emph{S}-wave contribution accounting for
of the total rate and that other components are
negligible. The parameters of the resonance and of the
form factors based on the spectroscopic pole dominance predictions are also
measured. We also present a measurement of the helicity
basis form factors in a model-independent way.Comment: 17 pages, 6 figure
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