742 research outputs found

    Frequentist and Bayesian Quantum Phase Estimation

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    Frequentist and Bayesian phase estimation strategies lead to conceptually different results on the state of knowledge about the true value of the phase shift. We compare the two frameworks and their sensitivity bounds to the estimation of an interferometric phase shift limited by quantum noise, considering both the cases of a fixed and a fluctuating parameter. We point out that frequentist precision bounds, such as the Cram\`er-Rao bound, for instance, do not apply to Bayesian strategies and vice-versa. Similarly, bounds for fluctuating parameters make no statement about the estimation of a fixed parameter.Comment: 4 figure

    Traveling wave phenomena in a nonlocal dispersal predator-prey system with the Beddington-DeAngelis functional response and harvesting

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    This paper is devoted to studying the existence and nonexistence of traveling wave solution for a nonlocal dispersal delayed predator-prey system with the Beddington-DeAngelis functional response and harvesting. By constructing the suitable upper-lower solutions and applying Schauder\u27s fixed point theorem, we show that there exists a positive constant c∗ such that the system possesses a traveling wave solution for any given c\u3ec∗. Moreover, the asymptotic behavior of traveling wave solution at infinity is obtained by the contracting rectangles method. The existence of traveling wave solution for c=c∗ is established by means of Corduneanu\u27s theorem. The nonexistence of traveling wave solution in the case of

    Cloud Point Extraction-HPLC Determination of Polycyclic Aromatic Hydrocarbons Residues in Traditional Chinese Medicinal Herbs

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    AbstractA method was developed for the analysis of polycyclic aromatic hydrocarbons (PAHs) residues in traditional Chinese medicinal herbs by using cloud point extraction combined with high performance liquid chromatography- fluorescence detection. Non-ionic surfactant Genapol X-080 was used for the cloud point extraction of five PAHs residues. Some important parameters influencing the extraction efficiency, such as the surfactant concentration, ultrasonic-assisted extraction time, liquid to solid ratio, salt concentration as well as the equilibration time and temperature, were investigated in detail. Experimental results showed that good linearity could be obtained in the concentration range of 0.05-20ng/ml for all the five PAHs with correlation coefficients between 0.9989 and 0.9999. Relative standard deviations for five replicate determinations of PAHs were between 4.6-6.6%. The established method has been successfully applied to the determination of PAHs residues in Rehmannia, Radix Isatidis, Rhizoma Coptidis, Root of Auricledleaf Swallowwort and Radix Scutellariae

    FBNet: Feedback Network for Point Cloud Completion

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    The rapid development of point cloud learning has driven point cloud completion into a new era. However, the information flows of most existing completion methods are solely feedforward, and high-level information is rarely reused to improve low-level feature learning. To this end, we propose a novel Feedback Network (FBNet) for point cloud completion, in which present features are efficiently refined by rerouting subsequent fine-grained ones. Firstly, partial inputs are fed to a Hierarchical Graph-based Network (HGNet) to generate coarse shapes. Then, we cascade several Feedback-Aware Completion (FBAC) Blocks and unfold them across time recurrently. Feedback connections between two adjacent time steps exploit fine-grained features to improve present shape generations. The main challenge of building feedback connections is the dimension mismatching between present and subsequent features. To address this, the elaborately designed point Cross Transformer exploits efficient information from feedback features via cross attention strategy and then refines present features with the enhanced feedback features. Quantitative and qualitative experiments on several datasets demonstrate the superiority of proposed FBNet compared to state-of-the-art methods on point completion task.Comment: The first two authors contributed equally to this work. The source code and model are available at https://github.com/hikvision-research/3DVision/. Accepted to ECCV 2022 as oral presentatio

    WDM transmission over 320 km EDFA-amplified SSMF using 30 Gb/s return-to-zero optical differential 8-level phase-shift keying (OD8PSK)

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    Fiber transmission of optical differential 8- level phase- shift keying ( OD8PSK) signals is demonstrated for the first time. Co- polarized 8 WDM channels of 10 Giga- symbol/ s or 30 Gb/ s return- to- zero ( RZ) OD8PSK signals with a channel spacing of 50 GHz were transmitted over 320 km of standard single mode fiber ( SSMF) with an EDFA spacing of 80 km. The BER of the worst WDM channel after transmission of 320 km was 2.3 x 10(-5)

    LAPTM4B-35 promotes cancer cell migration via stimulating integrin beta1 recycling and focal adhesion dynamics

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    Metastasis is the main cause of cancer patients' death despite tremendous efforts invested in developing the related molecular mechanisms. During cancer cell migration, cells undergo dynamic regulation of filopodia, focal adhesion, and endosome trafficking. Cdc42 is imperative for maintaining cell morphology and filopodia, regulating cell movement. Integrin beta1 activates on the endosome, the majority of which distributes itself on the plasma membrane, indicating that endocytic trafficking is essential for this activity. In cancers, high expression of lysosome-associated protein transmembrane 4B (LAPTM4B) is associated with poor prognosis. LAPTM4B-35 has been reported as displaying plasma membrane distribution and being associated with cancer cell migration. However, the detailed mechanism of its isoform-specific distribution and whether it relates to cell migration remain unknown. Here, we first report and quantify the filopodia localization of LAPTM4B-35: mechanically, that specific interaction with Cdc42 promoted its localization to the filopodia. Furthermore, our data show that LAPTM4B-35 stabilized filopodia and regulated integrin beta1 recycling via interaction and cotrafficking on the endosome. In our zebrafish xenograft model, LAPTM4B-35 stimulated the formation and dynamics of focal adhesion, further promoting cancer cell dissemination, whereas in skin cancer patients, LAPTM4B level correlated with poor prognosis. In short, this study establishes an insight into the mechanism of LAPTM4B-35 filopodia distribution, as well as into its biological effects and its clinical significance, providing a novel target for cancer therapeutics development.Peer reviewe

    A novel NH2-MIL-88B(Fe)-modified ceramic membrane for the integration of electro-Fenton and filtration processes: A case study on naproxen degradation

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    Process intensification based on innovative coupling between membrane microfiltration and catalytic oxidation technologies has become a promising strategy for water treatment. Here, a surface-nucleated metal-organic framework (MOF) was grown in situ to obtain an NH2-MIL-88B(Fe)-functionalized catalytic ceramic membrane (NH2-MIL-88B(Fe)@CM), whose ability to remove naproxen from water matrices via the so-called electro-Fenton with catalytic ceramic membrane (EFCCM) process was systematically investigated. The physicochemical properties of the NH2-MIL-88B(Fe) and membranes were characterized by XRD, FTIR, XPS and SEM, revealing the formation of a well-defined NH2-MIL-88B(Fe) layer on the porous CM with a thickness of around 13.5 μm, which provides a large amount of active sites for H2O2 activation to generate hydroxyl radical (¿OH). The EFCCM treatment of naproxen in Na2SO4 solution under recirculation batch mode yielded almost complete drug removal in 90 min at 50 mA, whereas the stability and catalyst loss tests gave evidence of good membrane reusability for 5 cycles. The treatment of naproxen in urban wastewater confronted severe membrane fouling, but this was effectively mitigated by combining hot water backwash with EF self-cleaning. Finally, the naproxen degradation routes involving 7 byproducts are proposed. This is an effective approach to the fabrication of CCM, which could be used for wastewater treatment in continuous mode as suggested by the minimal NPX content at the membrane outlet
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