The Solution of Two-Point Boundary Value Problem of a Class of Duffing-Type Systems with Non-C1 Perturbation Term

This paper deals with a two-point boundary value problem of a class of Duffing-type systems with non-C1 perturbation term. Several existence and uniqueness theorems were presented

Potential Role of lncRNA H19 as a Cancer Biomarker in Human Cancers Detection and Diagnosis: A Pooled Analysis Based on 1585 Subjects

Long noncoding RNAs (lncRNAs) have been reported to serve as diagnostic and prognostic biomarkers of cancers, which play vital roles in tumorigenesis and tumor progression. Several studies have been performed to explore diagnostic value of lncRNA H19 in cancer detection and diagnosis. However, there are still inconsistent results in diagnostic accuracy and reliability in individual studies. Therefore, the present study was performed to summarize the overall diagnostic performance of lncRNA H19 in cancer detection and diagnosis. A total of eight studies with 770 cases and 815 controls were included in this pooled analysis. The pooled diagnostic results were as follows: sensitivity, 0.69 (95%CI=0.62-0.76), specificity, 0.79 (95% CI=0.70-0.86), positive likelihood ratio (PLR), 3.31 (95%CI=2.29-4.78), negative likelihood (NLR), 0.39 (95%CI=0.31-0.49), diagnostic odds ratio (DOR), 8.53 (95%CI=4.99-14.60), and area under the curve (AUC), 0.79 (95%CI=0.76-0.83). Deeks’ funnel plot asymmetry test (P=0.13) suggested no potential publication bias. Our results indicated that lncRNA H19 had a relatively moderate accuracy in cancer detection and diagnosis. Further comprehensive prospective studies with large sample sizes are urgently required to validate our findings

The Preparation of g-C3N4/CoAl-LDH Nanocomposites and Their Depollution Performances in Cement Mortars under UV-Visible Light

In this study, new organic-inorganic g-C3N4/CoAl-LDH nanocomposites were prepared and introduced to fabricate photocatalytic cement mortars by internal mixing, coating, and spraying. The photocatalytic depollution of both g-C3N4/CoAl-LDH and cement mortars was assessed by NOx degradation reaction under UV-visible light irradiation. The study results suggested that the degradation efficiency of g-C3N4/CoAl-LDH nanocomposites improved with an increase in g-C3N4 content. The g-C3N4/CoAl-LDH1.5 nanocomposite displayed the highest NOx degradation capacity, which was about 1.23 and 3.21 times that of pure g-C3N4 and CoAl-LDH, respectively. The photocatalytic cement mortars which were all fabricated using different approaches could effectively degrade the target pollutants and exhibited significant compatibility between g-C3N4/CoAl-LDH and cementitious substrate. Among them, the coated mortars showed strong resistance to laboratory-simulated wearing and abrasion with a small decrease in degradation rate

The Preparation of g-C₃N₄/CoAl-LDH Nanocomposites and Their Depollution Performances in Cement Mortars under UV-Visible Light

In this study, new organic-inorganic g-C3N4/CoAl-LDH nanocomposites were prepared and introduced to fabricate photocatalytic cement mortars by internal mixing, coating, and spraying. The photocatalytic depollution of both g-C3N4/CoAl-LDH and cement mortars was assessed by NOx degradation reaction under UV-visible light irradiation. The study results suggested that the degradation efficiency of g-C3N4/CoAl-LDH nanocomposites improved with an increase in g-C3N4 content. The g-C3N4/CoAl-LDH1.5 nanocomposite displayed the highest NOx degradation capacity, which was about 1.23 and 3.21 times that of pure g-C3N4 and CoAl-LDH, respectively. The photocatalytic cement mortars which were all fabricated using different approaches could effectively degrade the target pollutants and exhibited significant compatibility between g-C3N4/CoAl-LDH and cementitious substrate. Among them, the coated mortars showed strong resistance to laboratory-simulated wearing and abrasion with a small decrease in degradation rate

A review on the pumping behavior of modern concrete

Pumping is the most common technique used to transport fresh concrete in construction sites. The large-scale use of concrete all over the world makes the pumping increasingly important. A wide variety of additives and admixtures are incorporated into modern concrete in order for sustainable development. The performance of modern concrete is rather complex and its pumping behavior differs significantly from that of conventional concrete, especially in the fresh stage. This paper presents a comprehensive overview on the state of the art of concrete pumping. The models and methods used for characterizing the concrete pumpability and lubrication layer are described. The factors influencing the pumping behavior are discussed. A couple of ultra-high pumping engineering of concrete conducted in China are introduced.</p

Inhibition of LncRNA-HRIM Increases Cell Viability by Regulating Autophagy Levels During Hypoxia/Reoxygenation in Myocytes

Backgrund/Aims: Ischemia reperfusion (I/R) promotes the severity of cardiomyocyte injury. Long noncoding RNAs (LncRNAs) are key regulators in cardiovascular diseases. However, the association between LncRNAs and myocardial I/R injury has not been thoroughly characterized to date. We attempted to clarify the potential biological role of a LncRNA (E230034O05Rik), which we named hypoxia/reoxygenation (H/R) injury-related factor in myocytes (HRIM), by investigating the differential expression of LncRNAs between groups of myocytes exposed to either a normal level of oxygen or to H/R. Methods: Microarray analysis was used to determine analyze the global differential expression of LncRNAs in H9c2 myocytes exposed either to a normal level of oxygen or to H/R. Target LncRNA levels were further verified in vitro and ex vivo by real-time polymerase chain reaction (qPCR). Cell viability was analyzed using the Cell Counting Kit-8 assay. Autophagy levels were confirmed by Western blotting, transmission electron microscopy, and autophagic double-labeled (mRFP-GFP-LC3) adenovirus analyses. Results: Gene expression profiling revealed that 797 LncRNAs and 1898 mRNAs were differentially expressed in the H/R group compared with the normal oxygen group. Among these LncRNAs and mRNAs, 6 upregulated LncRNAs and 2 downregulated LncRNAs in the H/R group were selected and further validated by qPCR in vitro and ex vivo. Additionally, LncRNA-HRIM was inhibited by specific siRNAs in H9c2 myocytes exposed to H/R. The inhibition of LncRNA-HRIM by siRNA prevented cell death by suppressing excessive autophagic activity in myocytes, This finding suggests a detrimental role of LncRNA-HRIM in the regulation of I/R injury. Conclusions: LncRNAs are involved in H/R injury of H9c2 myocytes. Inhibition of LncRNA-HRIM increased cell viability by reducing autophagy in myocytes during H/R

A New Perspective to Explore the Hydraulic Connectivity of Karst Aquifer System in Jinan Spring Catchment, China

Investigating the hydraulic connectivity of a complex karst aquifer system is an important research topic for sustainable operation and optimization layout of karst groundwater exploitation and recharge. However, the identification of preferential sites of recharge and exploitation is usually subject to regional hydrogeology conditions and the mechanisms of recharge and exploitation. The conventional research methods of hydraulic connectivity often have some limitations. In this study, we developed an improved grey amplitude relation model to explore the hydraulic connectivity in Jinan spring catchment and presented a quantized evaluation index water table fluctuation relation degree (WTFRD) using karst groundwater table data in Western Jinan and Jinan spring groups from 2014 to 2017. Results showed that the total WTFRD was 0.854 between Western Jinan and Jinan spring groups when the external distraction for karst groundwater table was the smallest, which was in high relation degree grade. Meanwhile, the change rules of karst groundwater table in the two sites were basically the same. Accordingly, a high connectivity occurred between the two karst aquifers from a statistical perspective, and further illustrated that Western Jinan could be selected as preferential experiment sites. A comprehensive case in Jinan spring catchment indicated that the WTFRD provided a preliminary idea to investigate hydraulic connectivity quantitatively. This method could be considered as a pre-study of the conventional experiments to form a high-efficiency and low-cost combined method, which has great potential and merits further study

Oxalis xishuiensis (Oxalidaceae), a new species from Danxia landforms in Guizhou, China

Oxalis xishuiensis, a new species of Oxalidaceae from Danxia landforms of Xishui County, Guizhou, China, is described and illustrated. It is morphologically similar to O. wulingensis by the two lateral leaflets arranged at about 180° angle and oblong pink petals with lilac veins, but clearly differs from the latter by leaflets almost as long as wide, obliquely obcordate lateral leaflets, shorter peduncles, longer capsule (1.2–1.5 cm vs. 0.5–0.7 cm) and alveolate seeds

Investigations of mixing technique on the rheological properties of self-compacting concrete

Rheological properties are of significant importance in successful placement and performance of self-compacting concrete (SCC). In this work, the rheological properties of SCC, combined with a powder-viscosity modifying admixture, were investigated based on a series of experimental studies. The modified Bingham model was applied to determine the rheological parameters and shear thickening behavior of SCC. The effects of mixing procedures, including charging sequence, mixing time and mixing speed, were analyzed. The results show that the shear thickening of SCC is reduced by first mixing the aggregate and water and then adding other raw materials. The direct contact between aggregate and water leads to a large amount of free water to be adsorbed by the aggregate system, resulting in an increase of the yield stress. In order to ensure an excellent fluidity and a low shear thickening behavior of SCC, the mixing time should be controlled at 4-5 min and the mixing speed at 30-45 r/min.Materials and Environmen