Study the Heavy Molecular States in Quark Model with Meson Exchange Interaction

Some charmonium-like resonances such as X(3872) can be interpreted as possible $D^{(*)}D^{(*)}$ molecular states. Within the quark model, we study the structure of such molecular states and the similar $B^{(*)}B^{(*)}$ molecular states by taking into account of the light meson exchange ($\pi$, $\eta$, $\rho$, $\omega$ and $\sigma$) between two light quarks from different mesons

The species of Tibetisoperla (Plecoptera: Perlodidae)

Two new species of the hitherto monotypic Tibetisoperla Huo & Du, 2021, T. elongata sp. nov., T. sclerotica sp. nov., are described, illustrated and compared with the type species and other Isoperlinae. Tibetisoperla and T. wangluyui Huo & Du, 2021 are newly recorded for Qinghai Province. © 2022, Museum National d'Histoire Naturelle. All rights reserved

SU(3)FSU(3)_F Meson Mass Formula from Random Phase Approximation

We present a $SU(3)_F$ meson mass formula from random phase approximation (RPA). Both the mesons of ground-state pseudoscalar octet and the ground-state vector octet are described quite well in this mass formula. We also estimate the current and constituent quark masses from the na\"{\i}ve quark model with the PCAC relation

Tumor Microenvironment Varies under Different TCM ZHENG Models and Correlates with Treatment Response to Herbal Medicine

In traditional Chinese medicine (TCM), diagnosis of pathology and choice of treatment prescriptions are based on a method of differentiation of signs and symptoms known as syndrome differentiation or ZHENG. The cornerstone of TCM, ZHENG, relies on the gathering of clinical information through inspection, auscultation and olfaction, inquiry, and palpation. However, the biomolecular basis of the ZHENG remains unclear. In this study, we established mouse xenograft pancreatic cancer models with Shi-Re (Dampness-Heat), Pi-Xu (Spleen-Deficiency), or Xue-Yu (Blood-Stasis) ZHENG, which are regarded as the three major ZHENGs in pancreatic cancer. We found that tumors of the different ZHENG models exhibited significantly altered cancer-associated fibroblast (CAF) proliferative activity and tumor-associated macrophage (TAM) infiltration, which led to altered levels of CAF- and TAM-derived secreted cytokines such as SDF-1 and CCL5. The ZHENG model type also significantly influenced tumor growth, and administration of herbal medicine to the ZHENG model modified the tumor microenvironment. Therefore, this study partially unveiled the molecular basis of TCM ZHENG in pancreatic cancer