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Power tests of a string of magnets comprising a full cell of the Superconducting Super Collider
In this paper we describe the operation and testing of a string of magnets comprising a full cell of the Superconducting Super Collider (SSC). The full cell configuration composed of ten dipoles, two quadrupoles, and three spool pieces is the longest SSC magnet string ever tested. Although the tests of the full cell were undertaken after the SSC project was marked for termination, their completion was deemed necessary and useful to future efforts at other accelerator laboratories utilizing Superconducting magnets. The focus of this work is on the electrical and cryogenic performance of the string components and the quench protection system with an emphasis on solving some of the questions concerning electrical performance raised during the previous two experimental runs involving a half cell configuration
Collider Scenario Implications of ASST Operation Superconducting Super Collider Laboratory Collider Scenario Implications of ASST Operation * Collider Scenario Implications of ASST Operation
Abstract After the achievement of the SSCL's Congressionally mandated milestone, the Accelerator System String Test (ASST) half cell under went a series of power tests. These tests involved quenches induced in various configurations and in power levels up to the maximum operation point. These tests have produced data which has defined various parameters and requirements for the individual elements and system
Enhancing Multistep DNA Processing by Solid-Phase Enzyme Catalysis on Polyethylene Glycol Coated Beads
Covalent immobilization of enzymes
on solid supports provides an
alternative approach to homogeneous biocatalysis by adding the benefits
of simple enzyme removal, improved stability, and adaptability to
automation and high-throughput applications. Nevertheless, immobilized
(IM) enzymes generally suffer from reduced activity compared to their
soluble counterparts. The nature and hydrophobicity of the supporting
material surface can introduce enzyme conformational change, spatial
confinement, and limited substrate accessibility, all of which will
result in loss of the immobilized enzyme activity. In this work, we
demonstrate through kinetic studies that flexible polyethylene glycol
(PEG) moieties modifying the surface of magnetic beads improve the
activity of covalently immobilized DNA replication enzymes. PEG-modified
immobilized enzymes were utilized in library construction for Illumina
next-generation sequencing (NGS) increasing the read coverage across
AT-rich regions