1 research outputs found
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Not AvailableA selective and sensitive multiresidue analysis method, comprising 4 7pesticides, was developed and
validated in tobacco matrix. The optimized sample preparation procedure in combination with gas
chromatography mass spectrometry in selected-ion-monitoring (GC-MS/SIM) mode offered limits of
detection (LOD) and quantification (LOQ) in the range of 3โ5 and 7.5โ15 ng/g, respectively, with recoveries
between 70 and 119% at 50โ100 ng/g fortifications. In comparison to the modified QuEChERS (Quick-Easy-
Cheap-Effective-Rugged-Safe method: 2 g tobacco + 10 ml water + 10 ml acetonitrile, 30 min vortexing,
followed by dispersive solid phase extraction cleanup), the method performed better in minimizing
matrix co-extractives e.g. nicotine and megastigmatrienone. Ambiguity in analysis due to co-elution of
target analytes (e.g. transfluthrin-heptachlor) and with matrix co-extractives (e.g. -HCH-neophytadiene,
2,4-DDE-linolenic acid) could be resolved by selective multi-dimensional (MD)GC heart-cuts. The method
holds promise in routine analysis owing to noticeable efficiency of 27 samples/person/day.Not Availabl