Separate areas for mirror responses and agency within the parietal operculum

There is common neural activity in parietal and premotor cortex when executing and observing goal-directed movements: the “mirror” response. In addition, active and passive limb movements cause overlapping activity in premotor and somatosensory cortex. This association of motor and sensory activity cannot ascribe agency, the ability to discriminate between self- and non-self-generated events. This requires that some signals accompanying self-initiated limb movement dissociate from those evoked by observing the action of another or by movement imposed on oneself by external force. We demonstrated associated activity within the medial parietal operculum in response to feedforward visual or somatosensory information accompanying observed and imposed finger movements. In contrast, the response to motor and somatosensory information during self-initiated finger and observed movements resulted in activity localized to the lateral parietal operculum. This ascribes separate functions to medial and lateral second-order somatosensory cortex, anatomically dissociating the agent and the mirror response, demonstrating how executed and observed events are distinguished despite common activity in widespread sensorimotor cortices

Postsecondary outcomes for students with disabilities related to employment and higher education

Students with disabilities are leaving high school and are not prepared. What is happening to students with disabilities after high school? Why? What can educators do to ensure that students with disabilities are successfully transitioning into the real world, which includes higher education institutions, long-term employment, and living independently? The purpose of this study was to examine existing data and determine what happened to students once they exited high school. The information provided insight for interested stakeholders on whether the outcomes of students with disabilities need to be improved. Examining the Wisconsin Statewide School District Post High School Outcomes Survey results will give special-education service providers a better understanding of the outcomes of the participants. The survey responses may help educators encourage students to make more informed choices on how to successfully accomplish their post-secondary goals. The survey results were analyzed in an effort to determine how many students were engaged in postsecondary activities in what specific areas. Are students with disabilities securing employment or attending higher education institutions after they leave high school? The state of Wisconsin requires that all students with disabilities to have documented plans before the students reach age fourteen. The transition plans are designed to help students begin to explore and pursue goals that are age appropriate and based upon their interest and abilities. Thousands of transition plans are written annually but are the majority of students accomplishing their post- secondary goals? Students were surveyed and answered a series forty-three interview questionnaire. The survey asked open-ended question that provided surveyors with a data on the students’ activities after they left high school. Transition has been and continues to be a significant area of focus for educators and researchers. There is a continuum of students exiting secondary settings on an annual basis. Thousands of students will be in need of an employment or training. The impact of the large number of students entering post-secondary settings indicates that professors and counselors will need to be equipped to provide accommodations

Difficult airways: a reliable “Plan B”

Percutaneous transtracheal jet ventilation (PTJV) is an accepted method of rescue ventilation following unsuccessful attempts to secure the airway through conventional methods. Pre-emptive use of PTJV in the difficult airway has also been described as using either a specifically designed jet ventilation catheter, or other cannulae, such as a central venous catheter (CVC). We report on the insertion of a single-lumen CVC to establish a means for PTJV or oxygen insufflation prior to induction of general anaesthesia in an 18-year-old man. He had an anticipated difficult airway and potentially difficult rescue airway access, having been booked for biopsy of neck masses and formal tracheostomy.Keywords: difficult airway, percutaneous jet ventilation, rescue ventilatio

An Investigation of Twenty/20 Vision in Reading

One functional anatomical model of reading, drawing on human neuropsychological and neuroimaging data, proposes that a region in left ventral occipitotemporal cortex (vOT) becomes, through experience, specialized for written word perception. We tested this hypothesis by presenting numbers in orthographical and digital form with two task demands, phonological and numerical. We observed a main effect of task on left vOT activity but not stimulus type, with increased activity during the phonological task that was also associated with increased activity in the left inferior frontal gyrus, a region implicated in speech production. Region-of-interest analysis confirmed that there was equal activity for orthographical and digital written forms in the left vOT during the phonological task, despite greater visual complexity of the orthographical forms. This evidence is incompatible with a predominantly feedforward model of written word recognition that proposes that the left vOT is a specialized cortical module for word recognition in literate subjects. Rather, the physiological data presented here fits better with interactive computational models of reading that propose that written word recognition emerges from bidirectional interactions between three processes: visual, phonological, and semantic. Further, the present study is in accord with others that indicate that the left vOT is a route through which nonlinguistic stimuli, perhaps high contrast two-dimensional objects in particular, gain access to a predominantly left-lateralized language and semantic system

The visual word form system in context

According to the “modular” hypothesis, reading is a serial feedforward process, with part of left ventral occipitotemporal cortex the earliest component tuned to familiar orthographic stimuli. Beyond this region, the model predicts no response to arrays of false font in reading-related neural pathways. An alternative “connectionist” hypothesis proposes that reading depends on interactions between feedforward projections from visual cortex and feedback projections from phonological and semantic systems, with no visual component exclusive to orthographic stimuli. This is compatible with automatic processing of false font throughout visual and heteromodal sensory pathways that support reading, in which responses to words may be greater than, but not exclusive of, responses to false font. This functional imaging study investigated these alternative hypotheses by using narrative texts and equivalent arrays of false font and varying the hemifield of presentation using rapid serial visual presentation. The “null” baseline comprised a decision on visually presented numbers. Preferential activity for narratives relative to false font, insensitive to hemifield of presentation, was distributed along the ventral left temporal lobe and along the extent of both superior temporal sulci. Throughout this system, activity during the false font conditions was significantly greater than during the number task, with activity specific to the number task confined to the intraparietal sulci. Therefore, both words and false font are extensively processed along the same temporal neocortical pathways, separate from the more dorsal pathways that process numbers. These results are incompatible with a serial, feedforward model of reading

Feedback from the IR Background in the Early Universe

It is commonly believed that the earliest stages of star-formation in the Universe were self-regulated by global radiation backgrounds - either by the ultraviolet Lyman-Werner (LW) photons emitted by the first stars (directly photodissociating H_2), or by the X-rays produced by accretion onto the black hole (BH) remnants of these stars (heating the gas but catalyzing H_2 formation). Recent studies have suggested that a significant fraction of the first stars may have had low masses (a few M_sun). Such stars do not leave BH remnants and they have softer spectra, with copious infrared (IR) radiation at photon energies around 1eV. Similar to LW and X-ray photons, these photons have a mean-free path comparable to the Hubble distance, building up an early IR background. Here we show that if soft-spectrum stars, with masses of a few M_sun, contributed more than 1% of the UV background (or their mass fraction exceeded 90%), then their IR radiation dominated radiative feedback in the early Universe. The feedback is different from the UV feedback from high-mass stars, and occurs through the photo-detachment of H^- ions, necessary for efficient H_2 formation. Nevertheless, we find that the baryon fraction which must be incorporated into low-mass stars in order to suppress H_2-cooling is only a factor of few higher than for high-mass stars.Comment: Accepted for publication in MNRAS (Letters). 5 pages with 2 figure

First direct observation of the Van Hove singularity in the tunneling spectra of cuprates

In two-dimensional lattices the electronic levels are unevenly spaced, and the density of states (DOS) displays a logarithmic divergence known as the Van Hove singularity (VHS). This is the case in particular for the layered cuprate superconductors. The scanning tunneling microscope (STM) probes the DOS, and is therefore the ideal tool to observe the VHS. No STM study of cuprate superconductors has reported such an observation so far giving rise to a debate about the possibility of observing directly the normal state DOS in the tunneling spectra. In this study, we show for the first time that the VHS is unambiguously observed in STM measurements performed on the cuprate Bi-2201. Beside closing the debate, our analysis proves the presence of the pseudogap in the overdoped side of the phase diagram of Bi-2201 and discredits the scenario of the pseudogap phase crossing the superconducting dome.Comment: 4 pages, 4 figure

The Decay D0→Kˉ∗0π−e+νeD^0\to \bar K^{*0} \pi^- e^+ \nu_e in the Context of Chiral Perturbation Theory

We study the decay $D^0\rightarrow \bar K^{*0} \pi^- e^+ \nu_e$, using $SU(2)_L \otimes SU(2)_R$ chiral perturbation theory for heavy charmed mesons and vector mesons, in the kinematic regime where $p_M \cdot p_\pi/m_M$ (here $M = D^0$ or $\bar K^{*0}$) is much smaller than the chiral symmetry breaking scale, $\Lambda_{\chi SB}$ ( $\Lambda_{\chi SB} \sim$ 1 GeV). We present the leading diagrams and amplitude, and calculate the rate, in the region where, to leading order in our calculations, the $\bar K^{*0}$ is at zero recoil in the $D^0$ rest frame. The rate thus calculated is given in terms of a known form factor and depends on the $DD^* \pi$ coupling constant $g_D$ of the heavy (charmed) meson chiral perturbation theory Lagrangian. A measurement of the above decay, in the aforementioned kinematic regime, can result in the extraction of an experimental value for $g_D$, accurate at the level of our approximations, and give us a measure of the validity of approaches based on chiral perturbation theory in studying similar processes.Comment: 17 pages, Latex, 2 embedded postscript figure