442 research outputs found

    Model Terintegrasi Penjadwalan Batch dan Pm dengan Kriteria Minimalisasi Biaya Simpan, Setup dan Pm pada Mesin dengan Increasing Failure Rate

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    Development of today's manufacturing systems leads to the getting shorter in product life cycle, more variety of products, as well as increasing in consumer demand for quality and timeliness. Thus the accuracy and speed of decision-making within the manufacturing system becomes important. This paper proposes an integrated model of batch scheduling and preventive maintenance scheduling, in assumption no non-conforming parts to the criteria of minimizing the total saving cost, setup cost, preventive maintenance cost in minimizing the actual flow time on a machine with increasing failure rate. An example is provided to show how the model and algorithm work

    Integrating Preventive Maintenance Scheduling as Probability Machine Failure and Batch Production Scheduling

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    This paper discusses integrated model of batch production scheduling and machine maintenance scheduling. Batch production scheduling uses minimize total actual flow time criteria and machine maintenance scheduling uses the probability of machine failure based on Weibull distribution. The model assumed no nonconforming parts in a planning horizon. The model shows an increase in the number of the batch (length of production run) up to a certain limit will minimize the total actual flow time. Meanwhile, an increase in the length of production run will implicate an increase in the number of PM. An example was given to show how the model and algorithm work

    Program Aplikasi Optimalisasi Perencanaan Produksi dengan Metode Goal Programming (Kasus CV. G)

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    Indonesia today is still a State agrarian. Thus agriculture in Indonesia always get more attention by the government. Many government programs are rolled out to support the agricultural development of Indonesia, and one of them is the fertilizer subsidy to farmers Indonesia. Fertilizer itself is very useful to nourish the soil and provide vitamins to the plants, thus increasing the amount of production generated. Therefore it is necessary fertilizer for agriculture in Indonesia. CV. G company is one of the companies that produce fertilizer. Fertilizer produced by this company is an organic fertilizer and inorganic fertilizer. Problems faced by these companies are in planning the production of fertilizer produced. Companies want to optimize the amount of production of each fertilizer, maximize revenues, minimize production costs, and simultaneously optimize the working hours of employees. To meet these objectives, this research created program package using goal programming methods. Goal programming method can provide an effective solution / equilibrium toward the goals set, and the calculation will be assisted by using the Simplex method that has been modified. This method is an extension of linear programming, linear programming which can only solve problems with a single goal while the goal programming to solve problems with multiple objectives

    Biota-sediment accumulation factor and concentration of heavy metals (Hg, Cd, As, Ni, Pb and Cu) in sediments and tissues of Chiton lamyi (Mollusca: Polyplacophora: Chitonidae) in Chabahar Bay, Iran

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    Heavy metals and some organic substances which are drained into the aquatic environments and cannot be decomposed or eliminated will sink into sediments or find their way into different levels of food chain. Bioaccumulation is the process of continuous deposition and aggregation of these substances into the body tissue of living organisms. Mollusks are remarkably appropriate to be used as bio-indicators because of their motionless or almost sessile nature, relatively high abundance, selective absorption of certain ions, and worldwide distribution in marine and inland aquatic habitats. Chiton lamyi is a sedentary species from the phylum, Polyplacophora, which is usually abundant on the rocky shores and intertidal zone of marine environments. Sediment and Chiton samples were taken from four stations of Chabahar Bay in autumn 2013. After acid digestion of samples, the concentration of heavy metals (mercury, cadmium, arsenic, nickel, lead and copper) were measured by the graphite furnace atomic absorption apparatus, and the bioaccumulation factor in relation to sediment was calculated. The highest concentration value was calculated as 3.28 for cadmium in the Hafte Tir station. The results of this study indicated that chitons can be used as an appropriate bio-indicator for heavy metals particularly cadmium pollution in the marine environment

    Identifying topics of interest of Mendeley users using the text mining and overlay visualization functionality of VOSviewer

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    This paper presents the results of a study in which we have analysed the topics of interest of Mendeley users (i.e. Students, PhDs, Post Docs, Researchers, Professors, Librarians, Lecturers & other Professionals) using text mining and visualization techniques. Beside analyzing topics of interest of Mendeley users, we have also identified fields of science for which readership information can be an interesting source of information complementary to citation information. For this purpose, we have used WoS citation data and Mendeley readership data for a set of 980,698 WoS publications (articles and reviews) with a DOI from 20111.The VOSviewer software tool (Van Eck & Waltman, 2010) was used to create so-called overlay visualizations. These visualizations show additional information on top of a base map. Two types of base maps were used. A base map containing the 250 WoS subject categories was used to analyze differences in readership activity across research fields and to analyze differences in interest between types of users. Base maps containing terms extracted from titles and abstracts using the text mining functionality of VOSviewer (Van Eck & Waltman, 2011) were used to analyze differences in readership activity within research fields. Merit, Expertise and Measuremen

    Evaluation of the frequency of the IL-28 polymorphism (rs8099917) in patients with chronic hepatitis C using zip nucleic acid probes, Kerman, Southeast of Iran

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    Polymorphisms in the region of the interleukin IL-28 gene on chromosome 19 have been related with clearance of hepatitis C virus (HCV), a major human pathogen responsible for chronic hepatitis, cirrhosis and hepatocellular carcinoma. About 3 of the world's population is infected with HCV. The long-term response to therapy is influenced by many host and viral factors, and recent evidence has indicated that some host genetic polymorphisms related to IL-28 are the most powerful predictors of virological response in patients with HCV. This study assessed frequency of the IL-28 polymorphism (rs8099917) in 50 patients (39 men and 11 women ) with chronic hepatitis C using ZNA probe real time PCR new method . All patients were tested for genotype of HCV and the HCV viral load. In parallel, the levels of SGOT, SGPT and ALK enzymes were assessed. Treatment using Peg-interferon alpha with ribavirin was conducted for patients and subsequently samples were collected to detect any change in viral load or liver enzyme rates. The overall frequency of the TT allele is 74, TG allele 20 and GG allele 6 and the percent of patients who had T allele was 84. Clear reduction in viral load and liver enzymes was reported in patients with the T allele. Especially for genotype 1 which is relatively resistant to treatment, these alleles may have a role in this decline. In conclusion, we showed that IL-28 polymorphism rs8099917 strongly predicts virological response in HCV infection and that real-time PCR with Zip nucleic acid probes is a sensitive, specific and rapid detection method for detection of SNPs which will be essential for monitoring patients undergoing antiviral therapy

    Pre-storage putrescine treatment maintains quality and prolongs postharvest life of Musa acuminata L.

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    The study was carried out to determine the effect of putrescine on quality and postharvest life of Musa acuminata L. during storage. The fruits were dipped at different concentrations of putrescine (0.5, 1 and 2 mM for 30 min) and distilled water as ‘control’. Changes in fruit quality attributes such as weight loss, firmness, skin color (L*, hue angle), total soluble solids (TSS), titratable acidity (TA), pH, ascorbic acid, polyphenol oxidase (PPO) and polygalacturonase (PG) enzymatic activity were calculated at harvest and after 5, 10, 15 and 20 days of storage at 0±1°C, 80-85% relative humidity. Weight loss, fruit softening, skin color changes, TSS, pH, the activity of PPO and PG increased during fruit ripening but the rate of changes was significantly slowed in putrescine treated fruits. Moreover, putrescine application maintained higher levels of TA, ascorbic acid and reduced the loss of sensory acceptability and decay incidence compared to control. In conclusion, the postharvest dip treatment of putrescine could be an effective means for extending the storage life of Musa acuminata L

    Comparison of metronidazole and ceftizoxime in prophylaxis of post-hysterectomy infections

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    Ceftizoxime is a common agent used in prophylaxis of infections after abdominal hysterectomy. Metronidazole could be used instead of ceftizoxime for this matter. To compare these two drugs, in a randomized clinical trial, 30 patients received metronidazole suppositories (1g) and 33 patients received intravenous ceftizoxime (1g) before surgery. There were not any significant demographic (age, weight, parity, hospitalization duration, pre-operation hemoglobin) differences between two groups. Also, the incision type and post-operation bleeding were the same in two groups. The complications after abdominal hysterectomy such as febrile morbidity, urinary tract infections and wound infections were not significantly different between two treatment groups. These results indicate that a single dose metronidazole has the same effect as ceftizoxime in infection prophylaxis of post-hysterectomy infection. Copyright © 2006 by Razi Institute for Drug Research (RIDR)
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