26 research outputs found
Mycobacterium marinum infection in Caviar fishes and fisherman's in a Caspian Sea Province in North of Iran
Mycobacterium marinum is the etiologic agent of fish tank granuloma in human. Determination of the fish tank granuloma in Fishermen and Mycobacterium marinum infection in Caviar fishes in Ashorade, in south east Caspian Sea were our objectives. Any suspected lesions in 387 subjects of Fishermen and 113 autopsy samples from gills of fish of Caviar were obtained and culture in Lowenstein Jensen media. The mycobacterial species were determined by conventional biochemical tests. No fish tank granuloma was proved in human, but 11 (9.73%) strains of Mycobacteria were isolated from Caviar fishes, that only 2 strains (1.76%) belong to M. marinum. © 2006 Asian Network for Scientific Information
SEISMIC PERFORMANCE EVALUATION OF REGULAR STEEL MOMENT FRAME BUILDINGS BASED ON FORCE, DIRECT DISPLACEMENT, ENERGY AND PLASTIC HINGE METHODS
Appropriate seismic design is based on real understanding of structural behavior. This requires precise perception of structural behavior during earthquakes which will beachieved by considering various codes' criteria. In other words, an ideal seismic design is
a method which directly considers non-linear behavior and designs frames in a way that they experience their maximum capacity, it means plastic hinges occur in frames. The plastic hinge locations should be far from joints between beams and columns. In this way, local instability does not occur. Actually, more accurate recognition of structural behavior during earthquakes is the main issue of this research. For this purpose, regular steel- moment frames with medium ductility and height were designed based on resistance (force), direct displacement, energy and plastic hinge methods. All the models were developed in OpenSees computer program, and they were analyzed through non-linear time history. Three records, according to record magnitude, fault distance, and soil type, were used from Pacific Earthquake Engineering Research Center (PEER) (Kobe, Northridge, and Tabas). Ultimately, these records were coordinated based on Iranian Standard No. 2800. Then, frames were evaluated with various codes' criteria in order to represent a new formula for maximum roof allowed displacement (for the purpose of controlling structural behavior after design).This formula is based on maximum displacement that frames have experienced during different earthquake records in non-linear time history analysis. The result indicates that the new formula allows more displacement to structures in comparison to Iranian Standard No. 2800. According to displacement time history of designed frames, at the beginning of the earthquake, the structures experienced severe impact and their nonlinear behavior was started. The transient displacement occurred when the first impact was applied to structure, and it was a displacement which happened along with the first plastic hinge occurrence. It makes sudden shock in displacement time history curve. With the passage of time, structures experienced variable displacements, and finally, a permanent displacement remained which is for the sake of nonlinear analyzing. Also, it can be inferred from the results that direct displacement and force methods present maximum and minimum base shears, respectively. In addition, in all frames, plastic hinge method provides maximum period value in comparison to other methods. It reveals that those frames which have been designed with plastic hinge method are more flexible. According to the results, the difference between direct displacement and energy methods period values is low, and period value of energy method is the minimum, as well
Safety climate and related factors in rehabilitation nurses of hospitals in Iran
BACKGROUND: Safety climate is a common insight of staff that indicates individuals' attitudes toward safety and priority of safety at work. OBJECTIVES: Nursing is a risky job where paying attention to safety is crucial. The assessment of the safety climate is one of the methods to measure the safety conditions in this occupation. The aim of this study was to assess the safety climate of rehabilitation nurses working in hospitals in Tehran. METHODS: This is a cross-sectional study which was carried out on 140 rehabilitation nurses selected from all hospitals and clinics in Tehran in 2019. To collect the required data, a two-section questionnaire was used. The first section was related to demographic factors and the second part (22 statements) was to measure the safety climate using nurses' safety climate assessment questionnaire. The collected data were analyzed by SPSS V16 using independent t-test, ANOVA, Kruskal-Wallis and Mann-Whitney U test at the 5 level. RESULTS: Findings showed that the total mean of safety climate was 3.06±0.56. According to the results, a significant difference was found between the positive and negative satisfaction of nurses with safety climates (P-value = 0.03), communication with nurses (P-value = 0.01) and supervisors' attitude (P-value = 0.02). Furthermore, a significant difference in safety climate between the individual with the second job and the individual without second could be observed (P-value = 0.01). CONCLUSIONS: The results indicated that the safety climate was not at an acceptable level. Thus, it is essential to introduce safety training courses (e.g. safety, work-rest balance, and so on) and to improve the safety performance at work. © 2021 - IOS Press. All rights reserved
Functionalized graphene oxide tablets for sample preparation of drugs in biological fluids: Extraction of ritonavir, a HIV protease inhibitor, from human saliva and plasma using LC–MS/MS
In this work, graphene oxide-based tablets (GO-Tabs) were prepared by applying a thin layer of functionalized GO on a polyethylene substrate. The GO was functionalized with amine groups (-NH2 ) by poly(ethylene glycol)bis(3-aminopropyl) terminated (GO-NH2 -PEG-NH2 ). The functionalized GO-Tabs were used for the extraction of ritonavir (RTV) in human saliva samples. RTV in plasma and saliva samples was analyzed using LC-MS/MS. Gradient LC system with MS/MS in the positive-ion mode [electrospray ionization (ESI+)] was used. The transitions m/z 721 → 269.0 and m/z 614 → 421 were used for RTV and the internal standard indinavir, respectively. This study determined the human immunodeficiency virus protease inhibitor RTV in human saliva samples using functionalized GO-Tab and LC-MS/MS, and the method was validated. The standard calibration curve for plasma and saliva samples was constructed from 5.0 to 2000 nmol L-1 . The limit of detection was 0.1 nmol L-1 , and the limit of quantification was 5.0 nmol L-1 in both plasma and saliva matrices. The intra- and inter-assay precision values were found to be between 1.5 and 5.8%, and the accuracy values ranged from 88.0 to 108% utilizing saliva and plasma samples. The extraction recovery was more than 80%, and the presented functionalized GO-Tabs could be reused for more than 10 extractions without deterioration in recovery