Ten-fold enhancement of InAs nanowire photoluminescence emission with an InP passivation layer

In this letter, we demonstrate that a significant improvement of optical performance of InAs nanowires can be achieved by capping the core InAs nanowires with a thin InP shell, which successfully passivates the surface states reducing the rate of non-radiative recombination. The improvements have been confirmed by detailed photoluminescence measurements, which showed up to ten-fold increase in the intensity of room-temperature photoluminescence from the capped InAs/InP nanowires compared to the sample with core-only InAs nanowires. Moreover, the nanowires exhibit high stability of total photoluminescence emission strength across temperature range from 10 to 300 K as a result of strong quantum confinement. These findings could be the key to successful implementation of InAs nanowires into optoelectronic devices

High expression level of the FTH1 gene is associated with poor prognosis in children with non-M3 acute myeloid leukemia

Acute myelogenous leukemia (AML) is a disease that severely affects the physical health of children. Thus, we aimed to identify biomarkers associated with AML prognosis in children. Using transcriptomics on an mRNA dataset from 27 children with non-M3 AML, we selected genes from among those with the top 5000 median absolute deviation (MAD) values for subsequent analysis which showed that two modules were associated with AML risk groups. Thus, enrichment analysis was performed using genes from these modules. A one-way Cox analysis was performed on a dataset of 149 non-M3 AML patients downloaded from the TCGA. This identified four genes as significant: FTH1, RCC2, ABHD17B, and IRAK1. Through survival analysis, FTH1 was identified as a key gene associated with AML prognosis. We verified the proliferative and regulatory effects of ferroptosis on MOLM-13 and THP-1 cells using Liproxstatin-1 and Erastin respectively by CCK-8 and flow cytometry assays. Furthermore, we assayed expression levels of FTH1 in MOLM-13 and THP-1 cells after induction and inhibition of ferroptosis by real-time quantitative PCR, which showed that upregulated FTH1 expression promoted proliferation and inhibited apoptosis in leukemia cells. In conclusion, high expression of FTH1 promoted proliferation and inhibited apoptosis of leukemic cells through the ferroptosis pathway and is thus a potential risk factor that affects the prognosis of non-M3 AML in children

Physiological and transcriptome analyses to infer regulatory networks in flowering transition of Rosa rugosa

Rosa rugosa is a famous Chinese traditional flowering species with high economic value. Flowering transition is an important process in plant growth and development. Although characterization of the flowering transition process has made great progress in some plants such as model plants, the process in R. rugosa has not been rigorously characterized to establish a mechanism. In this study, the changes of buds during flowering transition in R. rugosa ‘Duoji Huangmei’ were analyzed through transcriptomic sequencing combined with morphological and physiological index determinations. Results showed that with the morphology changes of buds, both sugar and starch content showed a similar up-down pattern while phytohormones content displayed various trends, which implied that sugar, starch and phytohormones might play diverse roles during flowering transition in R. rugosa. Moreover, a total of 4363 differentially expressed genes (DEGs) were identified at three developmental stages. Among them, 74 DEGs were involved in metabolism, transport, and signal transduction of sugar, starch, and phytohormones, as well as photoperiod and vernalization response. We proposed that these DEGs were not regulated independently but interacted with each other to construct a gene-gene network to regulate flowering transition of R. rugosa, and the regulatory network from vegetative growth stage (S1) to flowering transition stage (S2) was more complicated. These results further enriched the study of flowering transition in Rosa and lay an important foundation for breeding new varieties with desired floral traits

Growth of Pure Zinc-Blende GaAs(P) Core-Shell Nanowires with Highly Regular Morphology

The growth of self-catalyzed core–shell nanowires (NWs) is investigated systematically using GaAs(P) NWs. The defects in the core NW are found to be detrimental for the shell growth. These defects are effectively eliminated by introducing beryllium (Be) doping during the NW core growth and hence forming Be–Ga alloy droplets that can effectively suppress the WZ nucleation and facilitate the droplet consumption. Shells with pure zinc-blende crystal quality and highly regular morphology are successfully grown on the defect-free NW cores and demonstrated an enhancement of one order of magnitude for room-temperature emission compared to that of the defective shells. These results provide useful information on guiding the growth of high-quality shell, which can greatly enhance the NW device performance

Light-responsive nanogated ensemble based on polymer grafted mesoporous silica hybrid nanoparticles

Mesoporous silica nanoparticles grafted with light-responsive polymer on the outer surface were developed as novel nanogated ensembles, which allow encapsulation and release of drug and biological molecules under light irradiation.National Natural Science Foundation of China [20875079, 20835005]; Planned Science and Technology Project of Xiamen, China [3502z20080011]; Specialized Research Fund for the Doctoral Program of Higher Education of China [200803840007

Light-triggered covalent assembly of gold nanoparticles in aqueous solution

UV light irradiation triggers Au NPs that are respectively functionalized on the surface by o-nitrobenzyl alcohol and benzylamine to proceed with a covalent ligation reaction, which leads to assembling of Au NPs into anisotropic one-dimensional (1D) arrays in aqueous solution via indazolone linkages.National Natural Science Foundation of China[20875079, 20835005]; The Planned Science and Technology Project of Xiamen, China[3502z20080011]; Specialized Research Fund for Doctoral Program of Higher Education of China[200803840007

Kemnitz’ conjecture revisited

AbstractA conjecture of Kemnitz remained open for some 20 years: each sequence of 4n-3 lattice points in the plane has a subsequence of length n whose centroid is a lattice point. It was solved independently by Reiher and di Fiore in the autumn of 2003. A refined and more general version of Kemnitz’ conjecture is proved in this note. The main result is about sequences of lengths between 3p-2 and 4p-3 in the additive group of integer pairs modulo p, for the essential case of an odd prime p. We derive structural information related to their zero sums, implying a variant of the original conjecture for each of the lengths mentioned. The approach is combinatorial