39 research outputs found
Imperceptible Physical Attack against Face Recognition Systems via LED Illumination Modulation
Although face recognition starts to play an important role in our daily life,
we need to pay attention that data-driven face recognition vision systems are
vulnerable to adversarial attacks. However, the current two categories of
adversarial attacks, namely digital attacks and physical attacks both have
drawbacks, with the former ones impractical and the latter one conspicuous,
high-computational and inexecutable. To address the issues, we propose a
practical, executable, inconspicuous and low computational adversarial attack
based on LED illumination modulation. To fool the systems, the proposed attack
generates imperceptible luminance changes to human eyes through fast intensity
modulation of scene LED illumination and uses the rolling shutter effect of
CMOS image sensors in face recognition systems to implant luminance information
perturbation to the captured face images. In summary,we present a
denial-of-service (DoS) attack for face detection and a dodging attack for face
verification. We also evaluate their effectiveness against well-known face
detection models, Dlib, MTCNN and RetinaFace , and face verification models,
Dlib, FaceNet,and ArcFace.The extensive experiments show that the success rates
of DoS attacks against face detection models reach 97.67%, 100%, and 100%,
respectively, and the success rates of dodging attacks against all face
verification models reach 100%
Hyperforin Promotes Post-stroke Neuroangiogenesis via Astrocytic IL-6-Mediated Negative Immune Regulation in the Ischemic Brain
Hyperforin has been shown to be capable of promoting angiogenesis and functional recovery after ischemic stroke in our previous study. However, the exact mechanisms involved are not fully elucidated. In this study, adult male mice were subjected to 60-min transient middle cerebral artery occlusion followed by reperfusion for 28 days. Hyperforin was administrated to MCAO mice every 24 h for 2 weeks starting at 14 days post-ischemia (dpi). Then flow cytometry, quantitative Real-time PCR (RT-qPCR), western blotting, immunohistochemistry, and functional assays were performed to explore the molecular mechanisms in vivo and in vitro. Our data showed that hyperforin increased astrocytic interleukin (IL)-6 in the ischemic hemisphere via TLR4 at 28 dpi. The astrocytic IL-6 was essential to the promoting effects of hyperforin on the neural precursor cells proliferation, neuronal differentiation, angiogenesis, and functional recovery after stroke. Furthermore, hyperforin promoted the infiltration of regulatory T cells (Tregs) to the ischemic hemisphere and increased Tregs-derived cytokine IL-10 and transforming growth factor-β (TGF-β) in a manner that was dependent on astrocytic IL-6. Astrocytic IL-6 was critical to the role of hyperforin in promoting the infiltration of T-helper (Th) type 2 cells to the ischemic hemisphere and Th2-derived cytokine IL-4, relative to Th1 and Th1-derived cytokine interferon-γ (IFN-γ), which decreased during stroke recovery. After depletion of CD25+ Tregs, the promoting effects of hyperforin on post-stroke neurogenesis was attenuated. Moreover, blockade of IL-4 and TGF-β abrogated the promoting role of hyperforin in post-stroke neurogenesis, angiogenesis and functional recovery. Our results reveal a previously uncharacterized role of astrocytic IL-6-mediated negative immune regulation in the promoting effects of hyperforin on post-stroke neurovascular regeneration and functional recovery
Application of protection motivation theory in epidemic prevention in patients with respiratory diseases under the COVIDâ19 pandemic: A crossâsectional study
Abstract Objective This study aimed to investigate the effects of nursing intervention based on protection motivation theory (PMT) on patients with respiratory diseases in the context of the Coronavirus Disease 2019 (COVIDâ19) pandemic. Methods A total of 74 patients with respiratory diseases who were hospitalized from June 2020 to February 2021 were enrolled and stratified into a control group (nâ=â37) and an experimental group (nâ=â37) according to a stratified random sampling method. The control group adopted a routine nursing intervention program of the respiratory department, whereas the experimental group received a PMTâbased nursing intervention program on the basis of the control group. Chronic Disease SelfâManagement Study Measures (CDSMS) and SelfâEfficacy for Managing Chronic Diseases 6âitem Scale (SECD6) were used to evaluate the effect of PMT intervention before intervention, after 1âweek, and after 4âweeks of intervention. The levels of forced vital capacity (FVC), forced expiratory volume in 1 second (FEV1), FEV1/FVC and peak expiratory flow (PEF) were measured to evaluate pulmonary function. Results Before the intervention, there were no significant differences in the scores of CDSMS and SECD6 scales and liver function indexes between the two groups (pâ>â0.05). After 1 and 4âweeks of intervention, the scores of CDSMS and SECD6 scales of the experimental group were significantly higher than those of the control group (pââ0.05). Conclusion Nursing intervention based on PMT contributes to the improvement of selfâmanagement behaviors and selfâefficacy, which is conducive to the prognoses of patients
The early predictive roles of NLR and NE% in in-hospital mortality of septic patients
Background: This study aimed to retrospectively investigate the early predictive value of inflammation-related parameters in-hospital mortality of septic patients. Methods: We retrospectively recruited 606 patients from Wuhan Union Hospital from January 2009 to October 2022. The inflammation-related parameters including neutrophil-to-lymphocyte ratio (NLR), neutrophil percentage (NE%), platelet-to-lymphocyte ratio (PLR), and monocyte-to-lymphocyte ratio (MLR) in survivals and non-survivals on day 1, 2, 3 and 7 after hospitalization were collected and analyzed. Results: NLR and NE% in non-survivals (n = 185) were significantly higher than those in survivals (n = 421). The area under the receiver operating characteristic curve (AUC) of NLR or NE% was 0.880 or 0.852 on day 1, 0.770 or 0.790 on day 2, 0.784 or 0.777 on day 3, and 0.732 or 0.741 on day 7. The optimal cut-off values of NLR or NE% for predicting in-hospital mortality were 10.769 or 87.70% on day 1, 17.544 or 90.69% on day 2, 14.395 or 85.00% on day 3, and 9.105 or 83.93% on day 7. The day 1, 2 and 3 NLR and NE% were significant predictors of in-hospital mortality in the Cox proportional hazards models. Conclusions: NLR âĽ10.769 and NE% ⼠87.70% could be used early biomarkers for predicting in-hospital mortality of septic patients