5,695 research outputs found

    Three-Phase Detection and Classification for Android Malware Based on Common Behaviors

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    Android is one of the most popular operating systems used in mobile devices. Its popularity also renders it a common target for attackers. We propose an efficient and accurate three-phase behavior-based approach for detecting and classifying malicious Android applications. In the proposed approach, the first two phases detect a malicious application and the final phase classifies the detected malware. The first phase quickly filters out benign applications based on requested permissions and the remaining samples are passed to the slower second phase, which detects malicious applications based on system call sequences. The final phase classifies malware into known or unknown types based on behavioral or permission similarities. Our contributions are three-fold: First, we propose a self-contained approach for Android malware identification and classification. Second, we show that permission requests from an Application are beneficial to benign application filtering. Third, we show that system call sequences generated from an application running inside a virtual machine can be used for malware detection. The experiment results indicate that the multi-phase approach is more accurate than the single-phase approach. The proposed approach registered true positive and false positive rates of 97% and 3%, respectively. In addition, more than 98% of the samples were correctly classified into known or unknown types of malware based on permission similarities.We believe that our findings shed some lights on future development of malware detection and classification

    High-density lipoprotein cholesterol level as an independent protective factor against aggravation of acute pancreatitis: a case–control study

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    Background and aimsAt present, evidence on the association between high-density lipoprotein cholesterol (HDL-C) levels and aggravation of acute pancreatitis (AP) is limited. This study aimed to investigate the relationship between the lowest HDL-C level during intensive care units (ICU) stay and AP aggravation and to determine the optimum cutoff lowest HDL-C level.MethodsPatients admitted to the ICU of the Shandong Provincial Hospital for AP from 2015 to 2021 were included. The lowest HDL-C level during ICU stay was set as the independent variable, and the progression or non-progression to severe AP (SAP) was set as the dependent variable. Univariate and multivariate analyses were performed to determine the relationship between the two variables, and receiver operating characteristic (ROC) curves were plotted to analyze the predictive ability of the lowest HDL-C level for progression to SAP.ResultsThis study included 115 patients. The difference in the lowest HDL-C level between the SAP and moderately SAP groups was significant (P < 0.05). After adjusting for covariates, the lowest HDL-C level showed a negative correlation with the occurrence of SAP, with a relative risk of 0.897 (95% confidence interval: 0.827–0.973). The area under the ROC curve for prediction of AP aggravation by the lowest HDL-C level was 0.707, and the optimum cutoff lowest HDL-C level was 0.545 mmol/L.ConclusionNo less than 0.545 mmol/L of the HDL-C level during ICU stay may be an independent protective factor for the aggravation of AP

    Major Complications and Associated Risk Factors of Transrectal Ultrasound Guided Prostate Needle Biopsy: A Retrospective Study of 1875 Cases in Taiwan

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    Background/PurposeComplications from transrectal ultrasound (TRUS) guided prostate needle biopsy are occasionally encountered in the daily practice of urologists. We tried to determine the associated risk factors of patients who suffered from major complications that required hospitalization after TRUS guided prostate needle biopsies.MethodsWe did a retrospective review of 1875 TRUS guided prostate biopsies performed between January 2002 and December 2005. We defined major complications as patients with complications that needed hospitalization. We analyzed the association between biopsy complications and suspected factors, including age, prostate volume, patient's underlying disease, selection of prophylactic antibiotics, biopsy core numbers (6, 12, and 15 cores), and antiplatelet/anticoagulant usage.ResultsThere were 124 patients (6.6%) with major complication. These major complications were categorized as acute prostatitis (3.8%), acute urinary retention (2.1%), hematuria (1.9%), rectal bleeding (0.2%), epididymitis (0.2%), sepsis (0.05%), and vasovagal syncope (0.05%). Patients with larger prostate size were noted to have higher risk of developing transient acute prostatitis and acute urinary retention after prostate biopsy. In contrast, age, prophylactic antibiotics (levofloxacin and pipemidic acid), underlying diseases (diabetic mellitus, hypertension, hyperlipidemia, cerebrovascular accident, coronary artery disease), increased biopsy core numbers, and antiplatelet/anticoagulant usage were not associated with major complications after prostate biopsy.ConclusionTRUS guided prostate needle biopsy is a safe diagnostic tool in most elderly males with or without systemic underlying disease

    Effect of aramid core-spun yarn on impact resistance of aramid/epoxy composite

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    Introduction: The surface of aramid filament is smooth, which is a great defect for impact resistance and composite molding of aramid/epoxy composite. In this study, a new type of yarn—aramid core-spun yarn is introduced to the fabrication of compositematerials. It increases the friction among yarns and optimizes the performance of yarns.Methods: To verify the improvement of yarn in the composite material, the hand lay-up process is used, and the first layer and the fourth layer are replaced by core-spun yarns in a four-layer composite configuration.Results and Discussion: The energy absorption, and the damage of the impacted surface and the back surface are evaluated through the drop weight impact test. The yarn pull-out test can reflect the internal friction of fabric. The results show that the average energy absorption of new yarn in the first layer is 10 J cm2/g more than that in the fourth layer at a 90°/45°/-45°/0° configuration after the normalization, but the conclusion is contrary when the structure is -45°/0°/90°/45°. Under the structure of 90°/45°/-45°/0°, the damaged area of the fabric is larger when the aramid core-spun yarn is laid on the first layer, while a contrary result can be found for the structure of -45°/0°/90°/45°. The fundamental research will provide design ideas and supports for aramid composite

    The Impact of Single Session Intermittent Theta-Burst Stimulation over the Dorsolateral Prefrontal Cortex and Posterior Superior Temporal Sulcus on Adults with Autism Spectrum Disorder

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    Intermittent theta burst stimulation (iTBS), a patterned repetitive transcranial magnetic stimulation, was applied over the posterior superior temporal sulcus (pSTS) or dorsolateral prefrontal cortex (DLPFC) to explore its impact in adults with autism spectrum disorder (ASD). Among 25 adults with ASD, 19 (mean age: 20.8 years) completed the randomized, sham-controlled, crossover trial. Every participant received iTBS over the bilateral DLPFC, bilateral pSTS and inion (as a sham control stimulation) in a randomized order with a 1-week interval. Neuropsychological functions were assessed using the Conners' Continuous Performance Test (CCPT) and the Wisconsin Card Sorting Test (WCST). Behavioral outcomes were measured using the Yale-Brown Obsessive Compulsive Scale (Y-BOCS) and the Social Responsiveness Scale (SRS). In comparison to that in the sham stimulation, the reaction time in the CCPT significantly decreased following single DLPFC session (p = 0.04, effect size = 0.71) while there were no significant differences in the CCPT and WCST following single pSTS session. Besides, the results in behavioral outcomes were inconsistent and had discrepancy between reports of parents and patients. In conclusion, a single session of iTBS over the bilateral DLPFC may alter the neuropsychological function in adults with ASD. The impacts of multiple-sessions iTBS over the DLPFC or pSTS deserve further investigations

    Evolution of long centromeres in fire ants

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    Background: Centromeres are essential for accurate chromosome segregation, yet sequence conservation is low even among closely related species. Centromere drive predicts rapid turnover because some centromeric sequences may compete better than others during female meiosis. In addition to sequence composition, longer centromeres may have a transmission advantage. Results: We report the first observations of extremely long centromeres, covering on average 34 % of the chromosomes, in the red imported fire ant Solenopsis invicta. By comparison, cytological examination of Solenopsis geminata revealed typical small centromeric constrictions. Bioinformatics and molecular analyses identified CenSol, the major centromeric satellite DNA repeat. We found that CenSol sequences are very similar between the two species but the CenSol copy number in S. invicta is much greater than that in S. geminata. In addition, centromere expansion in S. invicta is not correlated with the duplication of CenH3. Comparative analyses revealed that several closely related fire ant species also possess long centromeres. Conclusions: Our results are consistent with a model of simple runaway centromere expansion due to centromere drive. We suggest expanded centromeres may be more prevalent in hymenopteran insects, which use haplodiploid sex determination, than previously considered

    Nanoscale III-V Semiconductor Photodetectors for High-Speed Optical Communications

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    Nanophotonics involves the study of the behavior of light on nanometer scale. Modern nanoscale semiconductor photodetectors are important building blocks for high-speed optical communications. In this chapter, we review the state-of-the-art 2.5G, 10G, and 25G avalanche photodiodes (APDs) that are available in commercial applications. We discuss the key device parameters, including avalanche breakdown voltage, dark current, temperature dependence, bandwidth, and sensitivity. We also present reliability analysis on wear-out degradation and optical/electrical overload stress. We discuss the reliability challenges of nanoscale photodetectors associated with device miniaturization for the future. The reliability aspects in terms of high electric field, Joule heating, and geometry inhomogeneity are highlighted

    Heisenberg-limited quantum metrology using 100-photon Fock states

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    Quantum metrology has emerged as a promising avenue for surpassing the limitations of classical mechanics in high-precision measurements. However, the practical implementation of quantum metrology is hindered by the challenges of manipulating exotic quantum states in large systems. Here, we propose and demonstrate a hardware-efficient approach to achieve Heisenberg-limited quantum metrology using large photon-number Fock states. We have developed a programmable photon number filter that efficiently generates Fock states with up to 100 photons in a high-quality superconducting microwave cavity. Using these highly nontrivial states in displacement and phase measurements, we demonstrate a precision scaling close to the Heisenberg limit and achieve a maximum metrological gain of up to 14.8 dB. Our hardware-efficient quantum metrology can be extended to mechanical and optical systems and provides a practical solution for high metrological gain in bosonic quantum systems, promising potential applications in radiometry and the search for new particles.Comment: Main text: 10 pages, 4 figures; Supplement: 16 pages, 9 figures, 1 tabl

    The Hidden Hydroxide in BaNiO3 Single Crystals Grown from a KOH Flux

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    Hexagonal oxide perovskites with one-dimensional chains of face-sharing MO6 octahedra are of enduring interest. Specifically, the hexagonal perovskite BaNiO3, prepared via non-ceramic approaches, acts as a highly functional catalyst for the oxygen-evolution reaction (OER) in alkaline media, with numerous studies focusing on this behavior, while its fundamental structural and physical properties have been somewhat overlooked. The current work is intiated by the observation of contrasting magnetic properties of BaNiO3 synthesized via KOH flux growth and high O2 pressure ceramic synthesis. To shed light on this difference, we have performed a series of rigorous analyses and found that the KOH flux-grown crystals made in open-air are actually a wet form of BaNiO3 that can be dried upon annealing in O2 flow but will then slowly degrade if stored under a condition where the O2 partial pressure is not high enough. Therefore, the present work not only provides insightful information to unveil a previously unknown aspect of the OER catalyst BaNiO3, but also rings a bell that the hidden hydroxide principle described here may also be applied to other hexagonal perovskite oxides prepared in wet conditions.Comment: 21 pages, 6 figure
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