188 research outputs found
Atomic hydrogen in the one-sided "compact double" radio galaxy 2050+364
European VLBI Network spectral imaging of the "compact double" radio source
2050+364 in the UHF band at 1049 MHz has resolved the HI absorbing region, and
has shown a faint continuum component to the North (N), in addition to the
well-known East-West double (E, W). Re-examination of VLBI continuum images at
multiple frequencies suggests that 2050+364 may well be a one-sided core-jet
source, which appears as a double over a limited frequency range. One of the
dominant features, W, would then be the innermost visible portion of the jet,
and could be at or adjacent to the canonical radio core. The other, E, is
probably related to shocks at a sudden bend of the jet, towards extended
steep-spectrum region N. A remarkably deep and narrow HI absorption line
component extends over the entire projected extent of 2050+364. It coincides in
velocity with the [OIII] optical doublet lines to within 10 km/s. This HI
absorption could arise in the atomic cores of NLR clouds, and the motion in the
NLR is then remarkably coherent both along the line-of-sight and across a
projected distance of > 300 pc on the plane of the sky. Broader, shallower HI
absorption at lower velocities covers only the plausible core area W. This
absorption could be due to gas which is either being entrained by the inner jet
or is flowing out from the accretion region; it could be related to the BLR.Comment: 10 pages, 7 figures. Accepted in A&
9. Management of captive animals
Husbandry interventions for captive breeding amphibians Expert assessors Kay Bradfield, Perth Zoo, Australia Jeff Dawson, Durrell Wildlife Conservation Trust, UK Devin Edmonds, Association Mitsinjo, Madagascar Jonathan Kolby, Honduras Amphibian Rescue and Conservation Center, Honduras Stephanie Jayson, Veterinary Department, Zoological Society of London, UK Daniel Nicholson, Queen Mary University of London, UK Silviu O. Petrovan, Cambridge University, UK and Froglife Trust, UK Jay Redbond, Wi..
Etiologic and epidemiologic analysis of bacterial infectious upper respiratory disease in Thoroughbred horses at the Seoul Race Park
Infectious upper respiratory disease (IURD) of Thoroughbred racehorses has been a frequent problem (29.6% of incidence) at the Seoul Race Park (Korea). Risk factors for IURD include the season with a high transfer rate (summer and fall), the stabling period (†3 months), and age (2 to 3 years old), suggesting that the movement and new environment may have depressed the immune system of the horses and decreased their ability to respond properly to pathogens. The bacterial strains (n = 98) isolated from IURD horses included Pseudomonas spp., Escherichia coli, Staphylococcus spp., Streptococcus equi subsp. equi and zooepidemicus
S.O.S. Pinna nobilis: A Mass Mortality Event in Western Mediterranean Sea
A mass mortality event (MME) impacting the bivalve Pinna nobilis was detected across a wide geographical area of the Spanish Mediterranean Sea (Western Mediterranean Sea) in early autumn 2016. Underwater visual censuses were conducted across several localities separated by hundreds of kilometers along the Spanish Mediterranean coasts and revealed worrying high mortality rates reaching up to 100% in the center and southernmost coasts of the Iberian Peninsula including Balearic Islands. Populations on the northern coasts of the Spanish Mediterranean Sea seemed to be unaffected (Catalonian region). Histological examination of affected individuals revealed the presence of a haplosporidan-like parasite within the digestive gland being probably the pathogen that causes this mortality. The present MME has spread rapidly, causing high mortality rates in infected populations. Taking into account the degree of impact, the geographic extent, and the high probability that the infection is still in a spreading phase, this might be considered the largest MME ever registered for P. nobilis up to date, forcing this emblematic bivalve into a critical viability status over hundreds of kilometers of coastVersiĂłn del edito
Insights into the Mechanistic Basis of Plasmid-Mediated Colistin Resistance from the Crystal Structure of the Catalytic Domain of MCR-1
The polymixin colistin is a "last line" antibiotic against extensively-resistant Gram-negative bacteria. Recently, the mcr-1 gene was identified as a plasmid-mediated resistance mechanism in human and animal Enterobacteriaceae, with a wide geographical distribution and many producer strains resistant to multiple other antibiotics. mcr-1 encodes a membrane-bound enzyme catalysing phosphoethanolamine transfer onto bacterial lipid A. Here we present crystal structures revealing the MCR-1 periplasmic, catalytic domain to be a zinc metalloprotein with an alkaline phosphatase/sulphatase fold containing three disulphide bonds. One structure captures a phosphorylated form representing the first intermediate in the transfer reaction. Mutation of residues implicated in zinc or phosphoethanolamine binding, or catalytic activity, restores colistin susceptibility of recombinant E. coli. Zinc deprivation reduces colistin MICs in MCR-1-producing laboratory, environmental, animal and human E. coli. Conversely, over-expression of the disulphide isomerase DsbA increases the colistin MIC of laboratory E. coli. Preliminary density functional theory calculations on cluster models suggest a single zinc ion may be sufficient to support phosphoethanolamine transfer. These data demonstrate the importance of zinc and disulphide bonds to MCR-1 activity, suggest that assays under zinc-limiting conditions represent a route to phenotypic identification of MCR-1 producing E. coli, and identify key features of the likely catalytic mechanism
Spin temperatures and covering factors for HI 21-cm absorption in damped Lyman-alpha systems
We investigate the practice of assigning high spin temperatures to damped
Lyman-alpha absorption systems (DLAs) not detected in HI 21-cm absorption. In
particular, Kanekar & Chengaulr (2003) have attributed the mix of 21-cm
detections and non-detections in low redshift (z<2.04) DLAs to a mix of spin
temperatures, while the non-detections at high redshift were attributed to high
spin temperatures. Below z=0.9, where some of the DLA host galaxy morphologies
are known, we find that 21-cm absorption is normally detected towards large
radio sources when the absorber is known to be associated with a large
intermediate (spiral) galaxy. Furthermore, at these redshifts, only one of the
six 21-cm non-detections has an optical identification and these DLAs tend to
lie along the sight-lines to the largest background radio continuum sources.
For these and many of the high redshift DLAs occulting large radio continua, we
therefore expect covering factors of less than the assumed/estimated value of
unity. This would have the effect of introducing a range of spin temperatures
considerably narrower than the current range of >9000 K, while still supporting
the hypothesis that the high redshift DLA sample comprises a larger proportion
of compact galaxies than the low redshift sample.Comment: Submitted to MNRAS, 11 pages, 6 figure
Flat-spectrum symmetric objects with ~1 kpc sizes I. The candidates
In order to understand the origin and evolution of radio galaxies, searches
for the youngest such sources have been conducted. Compact-medium symmetric
objects (CSO-MSOs) are thought to be the earliest stages of radio sources, with
possible ages of <10^3 yrs for CSOs (<1 kpc in size) and 10^4-10^5 yrs for MSOs
(1-15 kpc). From a literature selection in heterogeneous surveys, we have
established a sample of 37 confirmed CSOs. In addition, we only found three
confirmed flat-spectrum MSOs in the literature.
The typical CSO resides on a z<0.5 galaxy, has a flat radio spectrum
(a_thin<0.5; S_v proportional to v^-a), is <0.3 kpc in size, has an arm length
ratio <2, and well-aligned (theta<20 deg) opposite lobes with a flux density
ratio <10. In order to populate the 0.3-1 kpc size range (large CSOs) and also
in order to find more flat-spectrum MSOs, we have built a sample of 157 radio
sources with a_{1.40}^{4.85}<0.5 that were resolved with the VLA-A 8.4 GHz. As
first results, we have 'rediscovered' nine of the known CSO/MSOs while
identifying two new ~14 kpc MSOs and two candidate CSO/MSOs (which only lack
redshifts for final classification). We were able to reject 61 of the remaining
144 objects from literature information alone. In the series of papers that
starts with this one we plan to classify the remaining 83 CSO/MSO candidates
(thanks to radio and optical observations) as well as characterize the physical
properties of the (likely) many 0.3-15 kpc flat-spectrum CSO/MSOs to be found.Comment: 19 pages, 14 figures, 6 tables (note that Table 2, in landscape
format, has a separate file); accepted by MNRA
Characteristics of Non-typhoidal Salmonella Isolates from Human and Broiler-chickens in Southwestern Seoul, Korea
Non-typhoidal Salmonella (NTS) is an important commensal microorganism. The purpose of this study was to determine the epidemiological relation between NTS isolates from livestock and NTS isolates from human by analyzing antimicrobial susceptibilities and performing molecular typing. We determined the serotypes of 36 human clinical isolates and 64 livestock isolates, performed antimicrobial susceptibility testing against 8 antibiotics, and determined the molecular types of isolated NTS spp. by pulsed field gel electrophoresis (PFGE). In human isolates, S. enteritidis was the most common serotype (17 isolates; 47.2%) and S. typhimurium the second most (8 isolates; 22.2%). In livestock isolates, S. typhimurium was the most common serotype (15 isolates; 23.44%), and S. enteritidis was the second most (14 isolates; 21.88%). Ampicillin and tetracycline resistance were 50% (32/64 isolates) each among broiler-chicken NTS isolates. No human or livestock NTS isolates showed resistance to ciprofloxacin, TMP-SMX, or ceftriaxone. However, 19.4% (7/36) and 46.8% (30/64) of the human and livestock NTS isolates were resistant to nalidixic acid (MIC â„16 mg/mL), respectively. The presence of the three identical PFGE molecular types from human and broiler-chicken NTS isolates suggests the possibility of transmission from livestock to humans
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