Influence of instructional posters on cleanness of the hands after hand washing

本研究の目的は,手洗いポスターの違いによる手洗い消毒後の手洗いミスを比較することである｡調査対象は看護学生82名であった｡対象を41名ずつ2グループに分け,1グループには手洗い順序を示したポスターを,もう1グループには,手洗いミスを起こしやすい部位を図示したポスターを教材として与えた｡学生は,手指と手首に蛍光塗料を塗布後,抗菌石けんと流水による手洗い消毒を実施した｡次に蛍光塗料の残存状況を写真撮影後,画像処理し手洗いミスとして点数化した｡その結果,手洗いミスを起こしやすいポスターを使用したグループの方が,手洗い順序ポスターを用いたグループより手洗いミスが少ない傾向にあった｡なかでも手背側は,手洗いミスのポスターを使ったグループの方が手洗いミスは有意に少なかった(p<0.05)｡日常,手洗い場に掲示されているポスターは,手洗い順序を示したものが多い｡しかし,手洗いミスを起こしやすい部位を図示したポスターでも,手指衛生効果があることが示唆された｡The objective of this study was to compare the cleanness of the hands after following two different posters. The subjects were 82 nursing students. They were divided into 2 groups of 41 each. For instructions one group was given a poster showing the procedures of hand washing, and the other group was given a poster showing areas to be washed carefully. After a fluorescent dye was sprayed on the fingers and the wrists, the testees washed their hands with antimicrobial soap under running water. Then, the state of the remaining fluorescent dye was photographed. The images were processed, and the extent of hand washing was quantified. As a result, hand washing was more effective in the group given the poster showing areas to be washed carefully than in the other group. Particularly, the back of the hand was significantly cleaner in the former than in the latter group (p< 0.05). Many posters at hand-washing sites show the procedure of hand washing. However, a poster showing areas prone to poor hand washing seems to be more effective for ensuring cleanness of the hands

Clinicopathological significance of antinuclear antibodies in non-alcoholic steatohepatitis

金沢大学大学院医学系研究科がん細胞学Aim: Serum antinuclear antibodies (ANA) are occasionally noted in patients with non-alcoholic steatohepatitis (NASH). We examined the significance of ANA in NASH. Methods: We compared clinicopathological features in patients with ANA-positive NASH (n = 35) and ANA-negative NASH (n = 36). Inflammatory cell profiles and the distribution of oxidative stress markers were also examined immunohistochemically. Results: ANA-positive NASH was significantly associated with female gender (P = 0.005), high degree of portal inflammation (P = 0.039), interface activity (P = 0.036) and hepatocellular ballooning (P = 0.0008). In addition, ANA of high titer (320-fold or more) was significantly associated with the histological grade and stage of NASH (P = 0.02). The degree of steatosis wais rather mild in the high-titer ANA group(P = 0.01). The analysis of inflammatory cell profiles revealed that CD3-positive T cells were predominant and plasma cells were rather few in the portal area and hepatic lobules in both ANA-positive and ANA-negative groups. There was no difference in the distribution of oxidative stress markers between ANA-positive and ANA-negative groups. Conclusion: These findings suggest that the presence of ANA may be related to the progression of NASH and that a different type of autoimmune mechanism may be involved in the pathogenesis of NASH with ANA, compared to the pathogenesis of autoimmune hepatitis. © 2007 The Japan Society of Hepatology

Constraining the Movement of the Spiral Features and the Locations of Planetary Bodies within the AB Aur System

We present new analysis of multi-epoch, H-band, scattered light images of the AB Aur system. We used a Monte Carlo, radiative transfer code to simultaneously model the system's SED and H-band polarized intensity imagery. We find that a disk-dominated model, as opposed to one that is envelope dominated, can plausibly reproduce AB Aur's SED and near-IR imagery. This is consistent with previous modeling attempts presented in the literature and supports the idea that at least a subset of AB Aur's spirals originate within the disk. In light of this, we also analyzed the movement of spiral structures in multi-epoch H-band total light and polarized intensity imagery of the disk. We detect no significant rotation or change in spatial location of the spiral structures in these data, which span a 5.8 year baseline. If such structures are caused by disk-planet interactions, the lack of observed rotation constrains the location of the orbit of planetary perturbers to be >47 AU.Comment: 8 pages, 3 figures, 1 table, Accepted to Ap

Extreme Asymmetry in the Disk of V1247 Ori

We present the first near-infrared scattered-light detection of the transitional disk around V1247 Ori, which was obtained using high-resolution polarimetric differential imaging observations with Subaru/HiCIAO. Our imaging in the H band reveals the disk morphology at separations of ~0.14"-0.86" (54-330 au) from the central star. The polarized intensity (PI) image shows a remarkable arc-like structure toward the southeast of the star, whereas the fainter northwest region does not exhibit any notable features. The shape of the arm is consistent with an arc of 0.28" $\pm$ 0.09" in radius (108 au from the star), although the possibility of a spiral arm with a small pitch angle cannot be excluded. V1247 Ori features an exceptionally large azimuthal contrast in scattered, polarized light; the radial peak of the southeastern arc is about three times brighter than the northwestern disk measured at the same distance from the star. Combined with the previous indication of an inhomogeneous density distribution in the gap at $\lesssim$46 au, the notable asymmetry in the outer disk suggests the presence of unseen companions and/or planet-forming processes ongoing in the arc.Comment: 21 pages, 5 figures, accepted for publication in PAS

Extreme Asymmetry in the Polarized Disk of V1247 Orionis *

We present the first near-infrared scattered-light detection of the transitional disk around V1247 Ori, which was obtained using high-resolution polarimetric differential imaging observations with Subaru/HiCIAO. Our imaging in the H band reveals the disk morphology at separations of 0.′′14–0.′′86 (54–330 au) from the central star. The polarized intensity (PI) image shows a remarkable arc-like structure toward the southeast of the star, whereas the fainter northwest region does not exhibit any notable features. The shape of the arm is consistent with an arc of 0.′′28 0.′′09 in radius (108 au from the star), although the possibility of a spiral arm with a small pitch angle cannot be excluded. V1247 Ori features an exceptionally large azimuthal contrast in scattered, polarized light; the radial peak of the southeastern arc is about three times brighter than the northwestern disk measured at the same distance from the star. Combined with the previous indication of an inhomogeneous density distribution in the gap at < 46 au, the notable asymmetry in the outer disk suggests the presence of unseen companions and/or planet-forming processes ongoing in the arc.This work is supported by MEXT KAKENHI Nos. 23103005. S.K. acknowledges support from an STFC Ernest Rutherford Fellowship (ST/J004030/1) and Marie Curie CIG grant (SH-06192)