75 research outputs found
Construction of Instanton Solutions in Gauge Theory on Eight Dimensional Noncommutative Space(Abstracts of Doctoral Dissertations,Annual Report(from April 2003 to March 2004))
Eight Dimensional Noncommutative Instantons and D0-D8 Bound States with B-field
We construct some classes of instanton solutions of eight dimensional
noncommutative ADHM equations generalizing the solutions of eight dimensional
commutative ADHM equations found by Papadopoulos and Teschendorff, and
interpret them as supersymmetric - bound states in a NS -field.
Especially, we consider the - system with anti-self-dual -field
preserving 3/16 of supercharges. This system and self-duality conditions are
related with the group which is a subgroup of the eight dimensional
rotation group SO(8).Comment: 13 page
Cadherin activity is required for activity-induced spine remodeling
Neural activity induces the remodeling of pre- and postsynaptic membranes, which maintain their apposition through cell adhesion molecules. Among them, N-cadherin is redistributed, undergoes activity-dependent conformational changes, and is required for synaptic plasticity. Here, we show that depolarization induces the enlargement of the width of spine head, and that cadherin activity is essential for this synaptic rearrangement. Dendritic spines visualized with green fluorescent protein in hippocampal neurons showed an expansion by the activation of AMPA receptor, so that the synaptic apposition zone may be expanded. N-cadherin-venus fusion protein laterally dispersed along the expanding spine head. Overexpression of dominant-negative forms of N-cadherin resulted in the abrogation of the spine expansion. Inhibition of actin polymerization with cytochalasin D abolished the spine expansion. Together, our data suggest that cadherin-based adhesion machinery coupled with the actin-cytoskeleton is critical for the remodeling of synaptic apposition zone
Noncommutative U(1) Instantons in Eight Dimensional Yang-Mills Theory
We study the noncommutative version of the extended ADHM construction in the
eight dimensional U(1) Yang-Mills theory. This construction gives rise to the
solutions of the BPS equations in the Yang-Mills theory, and these solutions
preserve at least 3/16 of supersymmetries. In a wide subspace of the extended
ADHM data, we show that the integer which appears in the extended ADHM
construction should be interpreted as the -brane charge rather than the
-brane charge by explicitly calculating the topological charges in the case
that the noncommutativity parameter is anti-self-dual. We also find the
relationship with the solution generating technique and show that the integer
can be interpreted as the charge of the -brane bound to the -brane
with the -field in the case that the noncommutativity parameter is
self-dual.Comment: 22 page
Hypofractionated stereotactic radiotherapy for acoustic neuromas: safety and effectiveness over 8 years of experience.
Little information is available about long-term outcomes of hypofractionated stereotactic radiotherapy (hypo-FSRT) for acoustic neuromas. In this study, the safety and effectiveness of hypo-FSRT for unilateral acoustic neuroma were reviewed over 8 years of experience at our institution
CLICK:One-step generation of conditional knockout mice
Abstract Background CRISPR/Cas9 enables the targeting of genes in zygotes; however, efficient approaches to create loxP-flanked (floxed) alleles remain elusive. Results Here, we show that the electroporation of Cas9, two gRNAs, and long single-stranded DNA (lssDNA) into zygotes, termed CLICK (CRISPR with lssDNA inducing conditional knockout alleles), enables the quick generation of floxed alleles in mice and rats. Conclusions The high efficiency of CLICK provides homozygous knock-ins in oocytes carrying tissue-specific Cre, which allows the one-step generation of conditional knockouts in founder (F0) mice
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