80 research outputs found

    Iron silicide photonic crystals and light propagation property

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    AbstractWe report fabrication of iron silicide photonic crystals and properties of light propagation in β-FeSi2 two-dimensional (2D) or slab-type photonic crystals (PhC) designed to have their photonic band gaps near 1.55 μm. β-FeSi2 films were etched by neutral loop discharge reactive ion etching (NLD-RIE) which used a common Si process gas (SF6 + CHF3) system. We propose a new idea to reduce the reflection loss at light incidence. The idea is a characteristic PhC structure (called a conjugated PhC structure) in which inversion photonic patterns are fabricated at the incident interface and they have common photonic band-gap against the wavelength of propagating light. We confirmed large reduction of the reflection loss at the conjugated photonic structure

    The Th17/IL-23 Axis and Natural Immunity in Psoriatic Arthritis

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    Psoriatic arthritis (PsA) is a chronic inflammatory skin disease that causes enthesitis and destructive arthritis and significantly lowers patient quality of life. Recognition of the two target organs (the skin and joints) involved in the immunopathophysiology of PsA helped in elucidating the pathology of various systemic autoimmune diseases targeting multiple organs. Recent advances in immunology and genetics have made it clear that acquired immunity, especially that mediated by the Th17/IL-23 axis, plays an important role in the inflammatory pathology observed in psoriasis and PsA. Additionally, involvement of natural immunity has also been suggested. Microbial infection has been known to trigger psoriasis and PsA. Recent clinical studies using biopharmaceuticals, such as tumor-necrosis-factor- (TNF-) α inhibitors and IL-12/23 p40 antibodies, indicate that studies need not be based only on the immunological phenomena observed in PsA pathology since disease pathology can now be verified using human-based science. Considering this aspect, this paper discusses the immunopathology of PsA compared to psoriasis (cutaneous) and rheumatoid arthritis in humans and immunopathology of PsA with respect to the Th17/IL-23 axis and microbial infection

    Successful Extracorporeal Life Support for Life-threatening Hypercapnia with Bronchiolitis Obliterans after Allogeneic Hematopoietic Stem Cell Transplantation

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    Bronchiolitis obliterans (BO) is a disease with a poor prognosis, and a key factor that limits long-term survival after allogeneic hematopoietic stem cell transplantation (HSCT). We here report a case of a 31-year woman with acute lymphatic leukemia, which was treated by chemotherapy and HSCT, and consequently developed BO 2 years after HSCT. A non-tuberculous mycobacterial infection occurred and showed gradual exacerbation. She started taking anti-mycobacterial drugs, but lost appetite, felt tired and finally lost consciousness one month after beginning medication. Arterial blood gas revealed marked hypercapnia. Using extracorporeal life support (ECLS), the carbon dioxide concentration was reduced and her consciousness recovered. To our knowledge, this is the first case in which ECLS was successfully used for hypercapnia in a patient with BO

    IR Absorption Nnalysis of Oxidation Behaviors of Nano-composite Phases with β-FeSi2 Nanocrystals and Si

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    We have investigated oxidation behaviors of nano-composite phase with β-FeSi2 nanocrystals (β-NCs) and Si on Si substrates. IR absorption measurements revealed that only oxidation of Si into SiO2 proceeded in the nano-composite phase. This fact is very important for realization of a novel composite phase with β-NCs and SiO2, which may contribute to enhancement of light emission and to prevent a large thermal quenching of light emission observed in the composite phase with β-NCs and Si.International Conference and Summer School on Advanced Silicide Technology 2014, July 19–21, 2014, Tokyo, Japa

    Photoluminescence Enhancement of β-FeSi2 Nanocrystals Controlled by Transport of Holes in Cu-doped n-type Si Substrates

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    We have investigated PL behavior of β-FeSi2 nanocrystals controlled by transport of holes in Cu-doped n-type Si substrates. PL enhancement was observed and PCI-PL measurements revealed that PL enhancement was attributed to a transport process of holes with a larger time constant in Cu-doped n-Si substrate in which an interval trap process is controlled by Cu doping.International Conference and Summer School on Advanced Silicide Technology 2014, July 19–21, 2014, Tokyo, Japa

    Enhancement of Photoluminescence from Cu-doped β-FeSi2/Si Heterostructures

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    We have investigated photoluminescence (PL) behaviors of the Cu-doped β-FeSi2 thin film/Si heterostructure. Pronounced enhancement of an intrinsic A band and an impurity-related C band emissions has been observed in all the Cu-doped samples. The photo-carrier injection (PCI)-PL measurements have revealed that the PL enhancement is attributed to dynamic process of migration of holes where a repeated trap process of holes can be controlled by Cu-doping.International Conference and Summer School on Advanced Silicide Technology 2014, July 19–21, 2014, Tokyo, Japa

    Photoluminescence Property of Nano-composite Phases of β-FeSi2 Nanocrystals Embedded in SiO2

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    We have investigated photoluminescence (PL) behaviors of nano-composite phase of β-NCs embedded in SiO2 (β-NCs/SiO2). The inhomogeneous spectra consisting of the A, B, and C emission bands were observed. PL enhancement also was confirmed in comparison with β-NCs/Si. Under high pumping rate, we observed PL spectra near room temperatures (~270 K). This fact means that oxidation of the nano-composite phase can contribute to reduction of thermal quenching, which may come from increase of band offsets around β-NCs.International Conference and Summer School on Advanced Silicide Technology 2014, July 19–21, 2014, Tokyo, Japa

    Bacterial community shift as potential bioindicator for monitoring the performance of palm oil mill effluent treatment system

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    The growing demand for palm oil has caused a substantial increase in the generation of palm oil mill effluent (POME). POME has been known to give the adverse environmental impacts including land and aquatic ecosystem contamination and the biodiversity loss if it is not properly treated. In Malaysia, the biological ponding system is commonly being used to treat POME because of the low cost and less maintenance is required. However, the current wastewater treatment system for POME regularly fails to treat the effluent efficiently. To meet the standard discharge limit proposed by the Malaysian Department of the Environment, the POME must be treated effectively before being released into the receiving water bodies, hence monitoring a correct operation of POME treatment system is crucial. However, to date, only few studies have been conducted on the microbial aspects of POME and little is known about microbial diversity involved in the POME treatment system, either in terms of their community structure and function or their response to the environment. Therefore, the study on the microbial community composition of POME treatment system has been carried out which later can be used as potential bioindicator to monitor the performance of the treatment system. Sampling from POME treatment system was done by collecting samples from raw POME, anaerobic tanks, as well as from facultative and algae ponds. The shift of microbial community composition at each stage of POME treatment system has been shown by using PCR-Denaturing Gradient Gel Electrophoresis (DGGE) and Illumina Miseq. As a conclusion, a sensitive and accurate monitoring approach of POME treatment system using bacterial community shift is proposed to ensure a correct operation for POME treatment, hence can be used to complement the current physicochemical assessment method

    Bacterial community shift as potential bioindicator to indicate the river water contamination due to palm oil mill effluent final discharge

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    A thorough outlook on the effect of palm oil mill effluent (POME) final discharge towards the composition and functional status of bacterial community in the receiving river is provided in this study by using high-throughput MiSeq and flow cytometry, respectively. The shift of bacterial community dynamics could be used to determine the potential bacterial indicators to indicate contamination caused by POME. This study showed that the POME final discharge did not only alter the natural physicochemical properties of the river water but also caused the reduction of bacterial diversity in the receiving river. The Chromatiaceae and Alcaligenaceae which were not detected in the upstream but were detected in the downstream part of the river are proposed as the indicator bacteria to indicate the river water contamination caused by POME final discharge. The emergence of the potential indicator bacteria in the downstream part of the river was shown to be carried over by the effluent. Moreover, the functional status of the bacterial community at single-cell level is determined with regards to their abundance, viability and nucleic acid content to monitor the effect of POME final discharge in the affected river. The shift of low nucleic acid (LNA) to high nucleic acid (HNA) bacterial cells in the affected river suggests the transformation of dormant to active cells due to POME final discharge which may serves as potential bioindicator in the screening of anthropogenic effect due to POME final discharge in the river water with originally high LNA proportions. Monitoring the effluent discharge at low trophic level using MiSeq and flow cytometry is considered as an accurate pollution monitoring approach which can be used to complement the conventional POME pollution assessment method

    Microbial community changes in different stages of palm oil mill effluent treatment

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    The growing demand for palm oil has caused a substantial increase in the generation of palm oil mill effluent (POME). POME has been known to give the adverse environmental impacts including land and aquatic ecosystem contamination and the biodiversity loss if it is not properly treated. Currently, the wastewater treatment system for POME regularly fails to treat the effluent efficiently. To meet the standard discharge limit proposed by the Malaysian Department of the Environment, the POME must be treated effectively before being released into the receiving water bodies. In Malaysia, the ponding system is commonly being used to treat POME because of the low cost and less maintenance is required. To date, only few studies have been conducted on the microbial aspects of POME and little is known about microbial diversity involved in POME treatment, either in terms of their community structure and function or their response to the environment. Therefore, the study on the microbial community structure during POME treatment is proposed. Several samples from POME treatment system were collected, including POME samples from anaerobic tanks, as well as from facultative, and algae ponds. The changes of microbial community structure at each stage of POME treatment has been shown by using PCR-Denaturing Gradient Gel Electrophoresis (DGGE) approach. As a conclusion, the microbial community changes during POME treatment is expected to be explored and identified, hence will bring to the microbial community rebound after implementation of zero discharge system in the future
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