Near-field wireless power transfer and communication system design for corneal intraocular prosthetic device

This thesis reports the design of a novel intraocular projection device for the treatment of intractable corneal opacity, with a design emphasis on the simultaneous wireless power and data transfer system. Electronic ocular prosthetics (EOP) or artificial eyes are devices designed to deliver artificial visual stimuli to patients with blindness to partially restore their visual function. The need for wireless capabilities in EOPs arises from the highly limited physical space available for the intraocular implant devices. Early attempts at EOPs incorporated prohibitively large battery power sources and physical wire connections for the transmission of both power and information. However, one of the vital health regulations on medical implant devices involves the potential infection and inflammation caused by the implantation. Such regulations strictly prohibit the use of physical wire between the interbody and external-body components. This thesis presents a wireless power transfer (WPT) implementation that allows the battery to be kept outside of the patient’s body, significantly reducing the size of the implanted components, while still supplying energy to the implant without a signal exchange wire. The designed devices maintain the needed power and data exchange with the embedded parts while minimizing potential health complications from surgically inserted cables and bulky embedded hardware

To have or to do? Two essays on material and experiential purchases

Consumer researchers have documented that experiential purchases (i.e., those made with the primary intention of acquiring an experience) ultimately make consumers happier than do material purchases (i.e., those made with the primary intention of acquiring a tangible good or material possession; Van Boven and Gilovich 2003). Much of this research has focused on identifying the systematic differences between experiential and material purchases to understand why people drive greater benefits from acquiring an experience over a material possession (Caprariello and Reis 2013; Carter and Gilovich 2010; 2012; Van Boven and Gilovich 2003). However, less is known about when consumers tend to shift preferences toward experiential as opposed to material purchases, and how consumers make choices when choosing among options that are viewed as being more experiential versus material in nature. This dissertation is aimed at understanding situations in which consumers are particularly motivated to seek out experiential rather than material purchases and identifying a key factor that influences consumer choices between experiential and material purchases. Essay 1 investigates how thinking about one’s own death (i.e., mortality salience) influences consumer preferences for experiential versus material consumption. Specifically, I demonstrate that reminders of one’s own mortality lead consumers to seek to imbue their lives with a sense of meaning and to engage in more experiential than material consumption to fulfill their activated desire for meaning in response to mortality salience. In essay 2, I demonstrate that experiential (vs. material) consumption has the unique consequence of making consumers more attuned to the potential future affective consequences of their choice and more likely select options that are congruent with their ideal affective states (i.e., the qualitative type of positive affect that they would ideally like to feel, such as excitement or peacefulness). This tendency is enhanced when consumers are particularly motivated to regulate their affective states in ways that are consistent with ideal affect. Further, I show that consumers are more satisfied with their purchases over time when their choices are made in accordance with their ideal affect when the choice domain is experiential (vs. material).Business, Sauder School ofMarketing, Division ofGraduat

Near-field wireless power transfer and communication system design for corneal intraocular prosthetic device

This thesis reports the design of a novel intraocular projection device for the treatment of intractable corneal opacity, with a design emphasis on the simultaneous wireless power and data transfer system. Electronic ocular prosthetics (EOP) or artificial eyes are devices designed to deliver artificial visual stimuli to patients with blindness to partially restore their visual function. The need for wireless capabilities in EOPs arises from the highly limited physical space available for the intraocular implant devices. Early attempts at EOPs incorporated prohibitively large battery power sources and physical wire connections for the transmission of both power and information. However, one of the vital health regulations on medical implant devices involves the potential infection and inflammation caused by the implantation. Such regulations strictly prohibit the use of physical wire between the interbody and external-body components. This thesis presents a wireless power transfer (WPT) implementation that allows the battery to be kept outside of the patient’s body, significantly reducing the size of the implanted components, while still supplying energy to the implant without a signal exchange wire. The designed devices maintain the needed power and data exchange with the embedded parts while minimizing potential health complications from surgically inserted cables and bulky embedded hardware.U of I OnlyAuthor requested U of Illinois access only (OA after 2yrs) in Vireo ETD syste

Liquid Chromatography-Tandem Mass Spectrometry for Detecting Myosin Light Chain 3 in Dry-Aged Beef

Liquid chromatography-tandem mass spectrometry (LC/MS/MS) is a more accurate technique for detecting proteins than electrophoresis-based methods such as western blotting. Because of its convenience, western blotting is commonly used for protein analysis in beef. We developed a method for detecting myosin light chain 3 (myl3) in beef samples, particularly dry-aged beef, using LC/MS/MS for quality testing. Musculus longissimus dorsi of Holstein was aged for 0, 2, 4, 5, 9, 11, 17, 20, and 24 weeks and used to measure the myl3 concentration. Because of the high molecular weight of myl3, the limitations of LC/MS/MS were overcome by implementing immunoprecipitation and digestion steps. Ultimately, a tryptic fragment of myl3 (13-mer), generated using immunoprecipitation and digestion by a biotinylated antibody, was detected using LC-MS/MS in positive ion mode through multiple reaction monitoring and analyte separation on a C18 column. Our method showed limits of detection and quantification of less than 0.3 and 0.8 μg/kg, respectively. However, differences in the myl3 concentrations according to the aging time were not significant (p > 0.05). After 12 weeks, myl3 disappeared in tested all samples, thus our analytical method can be used for accurate measurement of muscle protein in beef samples