Building positive learning experiences through pedagogical research guide design

Library research guides are traditionally designed in a pathfinder-style format by resource type. However, would a pedagogical-style guide, which moves students through the research process, better support the student learning experience? This study sought to answer the question: Which guide design best supports the student information literacy learning experience outside of a classroom setting? This article reports results of a usability study (n=22) of first-year to graduate students who interacted with either a pedagogical or pathfinder-style research guide through a simulated research assignment. Results indicate that although there is no statistically significant performance difference between guide type, students using the pedagogical guide reported a more positive experience than those using the pathfinder guide. As a result, this led them to spend more time on, interact more with, and consult more resources on the research guide. Librarians who wish to enhance the usability of research guides may get greater student engagement by designing their guides pedagogically

An Empirical Investigation on the Role of IT Materiality in Multidisciplinary Innovation

Knowledge needs to traverse through social and cognitive boundaries as it is transformed from information to innovation. Little is known, however, regarding what, if any, role various IT material constraints and affordances play in supporting multidisciplinary innovations involving the complexities of heterogeneous knowledge. The notion of affordance has been used in Human Computer Interaction (HCI) to describe the action opportunities afforded by IT functionalities. By IT materiality, we refer to a set of “features that provide opportunities for and constraints on actions” (Leonardi and Barley 2008). We propose and empirically test a model to address this gap by drawing from the concepts of affordance, social structure theory, and the design of IT functionalities. We hypothesize that the impact of cognitive heterogeneity on innovation performance will be mediated by knowledge coordination and perspective taking. Further, we hypothesize that this relationship will be moderated by the material affordances of IT

Penetration depth of low-coherence enhanced backscattered light in sub-diffusion regime

The mechanisms of photon propagation in random media in the diffusive multiple scattering regime have been previously studied using diffusion approximation. However, similar understanding in the low-order (sub-diffusion) scattering regime is not complete due to difficulties in tracking photons that undergo very few scatterings events. Recent developments in low-coherence enhanced backscattering (LEBS) overcome these difficulties and enable probing photons that travel very short distances and undergo only a few scattering events. In LEBS, enhanced backscattering is observed under illumination with spatial coherence length L_sc less than the scattering mean free path l_s. In order to understand the mechanisms of photon propagation in LEBS in the subdiffusion regime, it is imperative to develop analytical and numerical models that describe the statistical properties of photon trajectories. Here we derive the probability distribution of penetration depth of LEBS photons and report Monte Carlo numerical simulations to support our analytical results. Our results demonstrate that, surprisingly, the transport of photons that undergo low-order scattering events has only weak dependence on the optical properties of the medium (l_s and anisotropy factor g) and strong dependence on the spatial coherence length of illumination, L_sc, relative to those in the diffusion regime. More importantly, these low order scattering photons typically penetrate less than l_s into the medium due to low spatial coherence length of illumination and their penetration depth is proportional to the one-third power of the coherence volume (i.e. [l_s \pi L_sc^2 ]^1/3).Comment: 32 pages(including 7 figures), modified version to appear in Phys. Rev.

Library Research Guides and the Learning Environment: Go Big or Go Home

In Fall 2016, librarians at Indiana University Bloomington and Indiana University Purdue University in Indianapolis undertook a pilot project to embed course-specific library research guides directly into Canvas course sites. With help from partners at IU's Information Technology division, we were able to install a software tool that uses metadata to connect course and research guides within the navigation menu of a Canvas course. This increased ability to seamlessly present expert research help, library services, and resources (both subscription-based and open educational content) within a learning ecosystem where students and faculty already operate, presented a wonderful opportunity to make this content discoverable. More importantly, integrating library content and research help directly into the LMS itself has promoted greater collaboration among librarians, students, and faculty, and allowed librarians to create a more customized learning environment for students to enhance their learning experience. In this session we will present results from our eight-month pilot, including faculty and student responses to these learning modules, as well as usage data. We will also discuss how this project enables libraries to provide both a consistent user interface and high-quality scholarly content to all students and faculty. Finally, our project presents a compelling opportunity for a more unified approach to information access needs not only across the entire Indiana University system, but among all Unizin institutions

Pedagogical v. Pathfinder: Reimagining Course & Research Guides for Student Success

What is the best way to design course and research guides? Can the design of a guide impact student learning and transform student information-seeking processes? This presentation will detail results of two studies (one in-classroom, the other usability) which use qualitative and quantitative assessments to determine if guide design aids in student learning. Draw on our successes and failures to invigorate your course and research guides for transformative learning

FE65 as a link between VLDLR and APP to regulate their trafficking and processing

<p>Abstract</p> <p>Background</p> <p>Several studies found that FE65, a cytoplasmic adaptor protein, interacts with APP and LRP1, altering the trafficking and processing of APP. We have previously shown that FE65 interacts with the ApoE receptor, ApoER2, altering its trafficking and processing. Interestingly, it has been shown that FE65 can act as a linker between APP and LRP1 or ApoER2. In the present study, we tested whether FE65 can interact with another ApoE receptor, VLDLR, thereby altering its trafficking and processing, and whether FE65 can serve as a linker between APP and VLDLR.</p> <p>Results</p> <p>We found that FE65 interacted with VLDLR using GST pull-down and co-immunoprecipitation assays in COS7 cells and in brain lysates. This interaction occurs via the PTB1 domain of FE65. Co-transfection with FE65 and full length VLDLR increased secreted VLDLR (sVLDLR); however, the levels of VLDLR C-terminal fragment (CTF) were undetectable as a result of proteasomal degradation. Additionally, FE65 increased cell surface levels of VLDLR. Moreover, we identified a novel complex between VLDLR and APP, which altered trafficking and processing of both proteins. Furthermore, immunoprecipitation results demonstrated that the presence of FE65 increased the interaction between APP and VLDLR <it>in vitro </it>and <it>in vivo</it>.</p> <p>Conclusions</p> <p>These data suggest that FE65 can regulate VLDLR trafficking and processing. Additionally, the interaction between VLDLR and APP altered both protein's trafficking and processing. Finally, our data suggest that FE65 serves as a link between VLDLR and APP. This novel interaction adds to a growing body of literature indicating trimeric complexes with various ApoE Receptors and APP.</p

Repression of FLOWERING LOCUS T Chromatin by Functionally Redundant Histone H3 Lysine 4 Demethylases in Arabidopsis

FLOWERING LOCUS T (FT) plays a key role as a mobile floral induction signal that initiates the floral transition. Therefore, precise control of FT expression is critical for the reproductive success of flowering plants. Coexistence of bivalent histone H3 lysine 27 trimethylation (H3K27me3) and H3K4me3 marks at the FT locus and the role of H3K27me3 as a strong FT repression mechanism in Arabidopsis have been reported. However, the role of an active mark, H3K4me3, in FT regulation has not been addressed, nor have the components affecting this mark been identified. Mutations in Arabidopsis thaliana Jumonji4 (AtJmj4) and EARLY FLOWERING6 (ELF6), two Arabidopsis genes encoding Jumonji (Jmj) family proteins, caused FT-dependent, additive early flowering correlated with increased expression of FT mRNA and increased H3K4me3 levels within FT chromatin. Purified recombinant AtJmj4 protein possesses specific demethylase activity for mono-, di-, and trimethylated H3K4. Tagged AtJmj4 and ELF6 proteins associate directly with the FT transcription initiation region, a region where the H3K4me3 levels were increased most significantly in the mutants. Thus, our study demonstrates the roles of AtJmj4 and ELF6 as H3K4 demethylases directly repressing FT chromatin and preventing precocious flowering in Arabidopsis

Polarization-selective vortex-core switching by orthogonal Gaussian-pulse currents

We experimentally demonstrate low-power-consumption vortex-core switching in magnetic nanodisks using tailored rotating magnetic fields that are produced with orthogonal and unipolar Gaussian-pulse currents. Optimal width of the orthogonal pulses and their time delay are found to be determined only by the angular eigenfrequency {\omega}_D for a given vortex-state disk of its polarization p, such that {\sigma} = 1/{\omega}_D and {\Delta}t = {\pi}p/2{\omega}_D, as studied from analytical and micromagnetic numerical calculations. The estimated optimal pulse parameters are in good agreements with the experimentally found results. This work provides a foundation for energy-efficient information recording in vortex-core cross-point architecture.Comment: 32 pages, 10 figure