Stability and morbidities of Le Fort I osteotomies with bioresorbable fixation - a randomized controlled trial

This journal suppl. entitled: Abstracts from the XVIIIth Congress of the European Association for Cranio-Maxillofacial Surgery, Barcelona, Spain, 12–15 September 2006INTRODUCTION: A randomized controlled clinical trial was conducted to compare bioresorbable with titanium mini-plates and screws in Le Fort I maxillary osteotomies for evaluation of clinical morbidities and stability. METHODS: Fourty patients requiring Le Fort I osteotomies were randomly assigned to 2 groups. One group received bioresorbable mini-plate fixation and the other received titanium plate fixation. Stability of the maxilla was determined by serial cephalometric analysis at 2 and 6 weeks and at 3, 6 and 12 months postoperatively. Subjective and objective assessment of clinical morbidities was evaluated prospectively. RESULTS: There were no differences in complications between the two groups. Maxillae with bioresorbable fixation were significantly more mobile at the second post-operative week. Bioresorbable plates were initially more easily palpable, but palpability decreased with time. Titanium plates became significantly palpable at the 1-year follow-up period. There was no difference in neurosensory disturbance. Maxillae with bioresorbable plate fixation showed significantly more upward displacement from the 2−6th post-operative week. The horizontal and angular relapses in the 2 groups were comparable. Bioresorbable fixation in Le Fort I osteotomy produces no more morbidities. CONCLUSIONS: Bioresorbable plate fixation is confirmed to be an acceptable alternative to l titanium mini-plate fixation in Le Fort I osteotomy. There were no significant differences in morbidities in the first year following the operation. The Le Fort I maxilla with bioresorbable fixation is expected to be slightly mobile within the first 6 post-operative weeks with associated superior displacement. The long-term stability of in horizontal and vertical planes was similar.link_to_subscribed_fulltex

Stability and morbidity of Le Fort I osteotomy with bioresorbable fixation: a randomized controlled trial

A randomized controlled clinical trial was conducted to compare the use of bioresorbable and titanium mini-plates and screws in Le Fort I maxillary osteotomies for evaluation of clinical morbidity and stability. Forty patients requiring Le Fort I osteotomies were randomly assigned to two groups. One group underwent bioresorbable mini-plate fixation and the other titanium mini-plate fixation. Stability of the maxilla was determined by serial cephalometric analysis at 2 and 6 weeks and at 3, 6 and 12 months postoperatively. Subjective and objective assessment of clinical morbidity was made prospectively. There were no differences in complications between the two fixation materials. Maxillae with bioresorbable fixation were significantly more mobile at the second postoperative week. Bioresorbable plates were initially more easily palpable, but their palpability decreased with time. Titanium plates became significantly more palpable at the 1-year follow-up. There was no difference in neurosensory disturbance between groups. Patients with bioresorbable plate fixation showed significantly more upward displacement in anterior maxilla following impaction and posterior maxilla following downgrafting from the 2nd to 6th postoperative week. The horizontal and angular relapses in the two groups were comparable. Le Fort I osteotomy with bioresorbable fixation results in no greater morbidity than with titanium fixation up to 1 postoperative year. © 2007 International Association of Oral and Maxillofacial Surgeons.link_to_subscribed_fulltex

Bone formation in defects grafted with different bone substitutes- an animal study

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