E-[4-(β-d-Allopyranos­yloxy)phen­yl]-1-(4-chloro­phen­yl)prop-2-enone ethanol solvate

The title compound, C21H21ClO7·C2H5OH was synthesized by the condensation reaction between helicid [systematic name: 4-(β-d-allopyranos­yloxy)benzaldehyde] and 4-chloro­aceto­phen­one in ethanol. In the mol­ecular structure, the pyran­oside ring adopts a chair conformation. In the crystal structure, the molecules are linked by inter­molecular O—H⋯O hydrogen bonds involving the OH groups from the pyran­oside unit and from the ethanol solvent mol­ecule

(E)-4-(β-d-Allopyran­os­yloxy)cinnamyl 4-bromo­phenyl ketone ethanol solvate

The title compound, C21H21BrO7·C2H6O, was synthesized by the Claisen–Schimidt reaction of helicid (systematic name: 4-formyl­phenyl-β-d-allopyran­oside) with 4-bromo­aceto­phenone in ethanol. The pyran ring adopts a chair conformation. In the crystal structure, mol­ecules are linked into a three-dimensional network by inter­molecular O—H⋯O hydrogen bonds

4-[1-Acetyl-3-(4-methoxy­phen­yl)-2-pyrazolin-5-yl]phenol

In the title compound, C18H18N2O3, the dihedral angle formed by the benzene rings is 71.75 (4)°. In the crystal structure, centrosymmetrically related mol­ecules are linked into dimers by inter­molecular O—H⋯O hydrogen bonds and π–π stacking inter­actions with centroid–centroid distances of 3.5511 (6) Å

(E)-1-(4-Chloro­phen­yl)-3-[4-(2,3,4,6-tetra-O-acetyl-β-d-allopyranos­yloxy)phen­yl]prop-2-en-1-one

The asymmetric unit of the title compound, C29H29ClO11, contains two independent mol­ecules of similar geometry, both adopting an E conformation about the C=C double bond. The dihedral angles formed by benzene rings are 10.73 (16) and 13.79 (18)°. The pyran­oside rings adopt a chair conformation. Intra­molecular C—H⋯O close contacts occur. The crystal packing is stabilized by inter­molecular C—H⋯O hydrogen bonds

1-[4-(2,3,4,6-Tetra-O-acetyl-β-d-allo­pyranos­yloxy)benzyl­idene]thio­semi­carbazide

The title compound, C22H27N3O10S, was synthesized by reaction of an ethanol solution of helicid (systematic name: 4-formylphenl-β-d-allopyranoside), thio­semicarbazide and acetic acid. The mol­ecule exhibits a trans conformation with respect to the C=N double bond. The pyran ring adopts a chair conformation. In the crystal structure, the mol­ecules are linked into chains parallel to the b axis by inter­molecular N—H⋯O hydrogen bonds

4-Formyl­phenyl 2,3,4,6-tetra-O-acetyl-β-d-allopyran­oside

The title compound, C21H24O11, crystallizes exclusively as the β-anomer. The substituent of the protected sugar at position C-3 is in the axial position, while all other groups are in equatorial positions. The pyran­oside ring adopts a stable chair conformation

Long-Term Prediction of Emergency Department Revenue and Visitor Volume Using Autoregressive Integrated Moving Average Model

This study analyzed meteorological, clinical and economic factors in terms of their effects on monthly ED revenue and visitor volume. Monthly data from January 1, 2005 to September 30, 2009 were analyzed. Spearman correlation and cross-correlation analyses were performed to identify the correlation between each independent variable, ED revenue, and visitor volume. Autoregressive integrated moving average (ARIMA) model was used to quantify the relationship between each independent variable, ED revenue, and visitor volume. The accuracies were evaluated by comparing model forecasts to actual values with mean absolute percentage of error. Sensitivity of prediction errors to model training time was also evaluated. The ARIMA models indicated that mean maximum temperature, relative humidity, rainfall, non-trauma, and trauma visits may correlate positively with ED revenue, but mean minimum temperature may correlate negatively with ED revenue. Moreover, mean minimum temperature and stock market index fluctuation may correlate positively with trauma visitor volume. Mean maximum temperature, relative humidity and stock market index fluctuation may correlate positively with non-trauma visitor volume. Mean maximum temperature and relative humidity may correlate positively with pediatric visitor volume, but mean minimum temperature may correlate negatively with pediatric visitor volume. The model also performed well in forecasting revenue and visitor volume

N-[4-(β-d-Allopyranos­yloxy)benzyl­idene]methyl­amine

The title compound, C14H19NO6, was synthesized by the condensation reaction between hecilid (4-formyl­phenl-β-d-allopyran­oside) and methyl­amine in methanol. In the crystal structure, the pyran ring adopts a chair conformation and adjacent mol­ecules are linked by inter­molecular O—H⋯O and O—H⋯N hydrogen bonds, forming a three-dimensional network

Kaposi’s sarcoma-associated herpesvirus seropositivity is associated with type 2 diabetes mellitus: A case–control study in Xinjiang, China

Objective: To assess the potential relationship between Kaposi’s sarcoma-associated herpesvirus (KSHV) infection and type 2 diabetes mellitus (DM-2) in Xinjiang, China. Methods: A case–control study of consecutively included DM-2 patients and normal controls was conducted among the Uygur and Han populations in Xinjiang Uygur Autonomous Region, China. Blood samples were collected and KSHV seroprevalence, antibody titers, and viral load were investigated. Logistic regression analysis and multiple linear regression analysis were applied to explore determinants of the main outcome measures. Results: A total of 324 patients with DM-2 and 376 normal controls were included. The seroprevalence of KSHV was 49.1% (95% confidence interval (CI) 43.6–54.5%) for diabetic patients and 23.7% (95% CI 19.4– 28.0%) for the control group. After adjusting for variables of ethnicity, sex, body mass index, occupation, educational level, marital status, age, and smoking and alcohol consumption habits, the association between DM-2 and KSHV infection still existed (odds ratio (OR) 2.94, 95% CI 2.05–4.22), and the risk of KSHV infection increased with glucose concentration (OR 1.35, 95% CI 1.21–1.51). KSHV was more likely to express both the latent and lytic antigens in diabetic patients (latent: OR 3.27, 95% CI 2.25–4.75; lytic: OR 3.99, 95% CI 2.68–5.93). Antibody titers and viral load increased in patients with higher blood glucose levels (p \u3c 0.001). Conclusions: Patients with DM-2 have an elevated risk of KSHV infection. Both antibody titers and viral load increased with blood glucose levels