17,411 research outputs found

    Spectrum and Thermodynamics of the one-dimensional supersymmetric t-J model with 1/r21/r^2 exchange and hopping

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    We derive the spectrum and the thermodynamics of the one-dimensional supersymmetric t-J model with long range hopping and spin exchange using a set of maximal-spin eigenstates. This spectrum confirms the recent conjecture that the asymptotic Bethe-ansatz spectrum is exact. By empirical determining the spinon degeneracies of each state, we are able to explicitly construct the free energy.Comment: 13 pages, Latex, (published in PRB46, 6639 (1992)

    HOW AGN JETS HEAT the INTRACLUSTER MEDIUM - INSIGHTS from HYDRODYNAMIC SIMULATIONS

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    © 2016. The American Astronomical Society. All rights reserved. Feedback from active galactic nuclei (AGNs) is believed to prevent catastrophic cooling in galaxy clusters. However, how the feedback energy is transformed into heat, and how the AGN jets heat the intracluster medium (ICM) isotropically, still remain elusive. In this work, we gain insights into the relative importance of different heating mechanisms using three-dimensional hydrodynamic simulations including cold gas accretion and momentum-driven jet feedback, which are the most successful models to date in terms of reproducing the properties of cool cores. We find that there is net heating within two "jet cones" (within ∼30° from the axis of jet precession) where the ICM gains entropy by shock heating and mixing with the hot thermal gas within bubbles. Outside the jet cones, the ambient gas is heated by weak shocks, but not enough to overcome radiative cooling, therefore, forming a "reduced" cooling flow. Consequently, the cluster core is in a process of "gentle circulation" over billions of years. Within the jet cones, there is significant adiabatic cooling as the gas is uplifted by buoyantly rising bubbles; outside the cones, energy is supplied by the inflow of already-heated gas from the jet cones as well as adiabatic compression as the gas moves toward the center. In other words, the fluid dynamics self-adjusts such that it compensates and transports the heat provided by the AGN, and hence no fine-tuning of the heating profile of any process is necessary. Throughout the cluster evolution, turbulent energy is only at the percent level compared to gas thermal energy, and thus turbulent heating is not the main source of heating in our simulation

    A totally Self-Checking Dynamic Asynchronous Datapath

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    This paper investigates the inherent totally self-checking (TSC) property of one type of dynamic asynchronous datapath based on Differential Cascode Voltage Logic (DCVSL). As a result, a totally self-checking dynamic asynchronous datapath architecture is proposed. It is simpler than other similar approaches and represents a new approach to fault tolerant design.published_or_final_versio

    Determinant representations of scalar products for the open XXZ chain with non-diagonal boundary terms

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    With the help of the F-basis provided by the Drinfeld twist or factorizing F-matrix for the open XXZ spin chain with non-diagonal boundary terms, we obtain the determinant representations of the scalar products of Bethe states of the model.Comment: Latex file, 28 pages, based on the talk given by W. -L. Yang at Statphys 24, Cairns, Australia, 19-23 July, 201

    Flavor SU(3) symmetry and QCD factorization in BPPB \to PP and PVPV decays

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    Using flavor SU(3) symmetry, we perform a model-independent analysis of charmless Bˉu,d(Bˉs)PP, PV\bar B_{u,d} (\bar B_s) \to PP, ~PV decays. All the relevant topological diagrams, including the presumably subleading diagrams, such as the QCD- and EW-penguin exchange diagrams and flavor-singlet weak annihilation ones, are introduced. Indeed, the QCD-penguin exchange diagram turns out to be important in understanding the data for penguin-dominated decay modes. In this work we make efforts to bridge the (model-independent but less quantitative) topological diagram or flavor SU(3) approach and the (quantitative but somewhat model-dependent) QCD factorization (QCDF) approach in these decays, by explicitly showing how to translate each flavor SU(3) amplitude into the corresponding terms in the QCDF framework. After estimating each flavor SU(3) amplitude numerically using QCDF, we discuss various physical consequences, including SU(3) breaking effects and some useful SU(3) relations among decay amplitudes of BˉsPV\bar B_s \to PV and BˉdPV\bar B_d \to PV.Comment: 47 pages, 3 figures, 28 table

    A validation of the Oswestry Spinal Risk Index

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    Purpose The purpose of this study was to validate the Oswestry Spinal Risk Index (OSRI) in an external population. The OSRI predicts survival in patients with metastatic spinal cord compression (MSCC). Methods We analysed the data of 100 patients undergoing surgical intervention for MSCC at a tertiary spinal unit and recorded the primary tumour pathology and Karnofsky performance status to calculate the OSRI. Logistic regression models and survival plots were applied to the data in accordance with the original paper. Results Lower OSRI scores predicted longer survival. The OSRI score predicted survival accurately in 74% of cases (p = 0.004). Conclusions Our study has found that the OSRI is a significant predictor of survival at levels similar to those of the original authors and is a useful and simple tool in aiding complex decision making in patients presenting with MSC

    Forward-backward Asymmetry and Branching Ratio of B \rar K_1 \ell^+ \ell^- Transition in Supersymmetric Models

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    The mass eigen states K1(1270)K_1(1270) and K1(1400)K_1(1400) are mixture of the strange members of two axial-vector SU(3) octet, 3P1(K1A)^3P_1(K_1^A) and 1P1(K1B)^1P_1(K_1^B). Taking into account this mixture, the forward-backward asymmetry and branching ratio of B \rar K_1(1270,1400) \ell^+ \ell^- transitions are studied in the framework of different supersymmetric models. It is found that the results have considerable deviation from the standard model predictions. Any measurement of these physical observables and their comparison with the results obtained in this paper can give useful information about the nature of interactions beyond the standard model.Comment: 14 pages, 4 figure

    Engineering a BCR-ABL-activated caspase for the selective elimination of leukemic cells.

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    Increased understanding of the precise molecular mechanisms involved in cell survival and cell death signaling pathways offers the promise of harnessing these molecules to eliminate cancer cells without damaging normal cells. Tyrosine kinase oncoproteins promote the genesis of leukemias through both increased cell proliferation and inhibition of apoptotic cell death. Although tyrosine kinase inhibitors, such as the BCR-ABL inhibitor imatinib, have demonstrated remarkable efficacy in the clinic, drug-resistant leukemias emerge in some patients because of either the acquisition of point mutations or amplification of the tyrosine kinase, resulting in a poor long-term prognosis. Here, we exploit the molecular mechanisms of caspase activation and tyrosine kinase/adaptor protein signaling to forge a unique approach for selectively killing leukemic cells through the forcible induction of apoptosis. We have engineered caspase variants that can directly be activated in response to BCR-ABL. Because we harness, rather than inhibit, the activity of leukemogenic kinases to kill transformed cells, this approach selectively eliminates leukemic cells regardless of drug-resistant mutations

    An assessment of validity and responsiveness of generic measures of health-related quality of life in hearing impairment

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    This article is made available through the Brunel Open Access Publishing Fund. This article is distributed under the terms of the Creative Commons Attribution License which permits any use, distribution, and reproduction in any medium, provided the original author(s) and the source are credited.Purpose: This review examines psychometric performance of three widely used generic preference-based measures, that is, EuroQol 5 dimensions (EQ-5D), Health Utility Index 3 (HUI3) and Short-form 6 dimensions (SF-6D) in patients with hearing impairments. Methods: A systematic search was undertaken to identify studies of patients with hearing impairments where health state utility values were measured and reported. Data were extracted and analysed to assess the reliability, validity (known group differences and convergent validity) and responsiveness of the measures across hearing impairments. Results: Fourteen studies (18 papers) were included in the review. HUI3 was the most commonly used utility measures in hearing impairment. In all six studies, the HUI3 detected difference between groups defined by the severity of impairment, and four out of five studies detected statistically significant changes as a result of intervention. The only study available suggested that EQ-5D only had weak ability to discriminate difference between severity groups, and in four out of five studies, EQ-5D failed to detected changes. Only one study involved the SF-6D; thus, the information is too limited to conclude on its performance. Also evidence for the reliability of these measures was not found. Conclusion: Overall, the validity and responsiveness of the HUI3 in hearing impairment was good. The responsiveness of EQ-5D was relatively poor and weak validity was suggested by limited evidence. The evidence on SF-6D was too limited to make any judgment. More head-to-head comparisons of these and other preference measures of health are required.Medical Research Counci

    New Mechanics of Traumatic Brain Injury

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    The prediction and prevention of traumatic brain injury is a very important aspect of preventive medical science. This paper proposes a new coupled loading-rate hypothesis for the traumatic brain injury (TBI), which states that the main cause of the TBI is an external Euclidean jolt, or SE(3)-jolt, an impulsive loading that strikes the head in several coupled degrees-of-freedom simultaneously. To show this, based on the previously defined covariant force law, we formulate the coupled Newton-Euler dynamics of brain's micro-motions within the cerebrospinal fluid and derive from it the coupled SE(3)-jolt dynamics. The SE(3)-jolt is a cause of the TBI in two forms of brain's rapid discontinuous deformations: translational dislocations and rotational disclinations. Brain's dislocations and disclinations, caused by the SE(3)-jolt, are described using the Cosserat multipolar viscoelastic continuum brain model. Keywords: Traumatic brain injuries, coupled loading-rate hypothesis, Euclidean jolt, coupled Newton-Euler dynamics, brain's dislocations and disclinationsComment: 18 pages, 1 figure, Late
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