Research progress on Traditional Chinese Medicine of pathogenesis and syndrome differentiation type for treating diabetes foot

糖尿病足（DF）是糖尿病的慢性并发症之一，也是糖尿患者致残甚至致死的重要原因。本文总结近期文献，对DF的中医病机、辨证分型等方面进行归纳，期望中医辨证与现代生命科学技术相结合，提高辨证准确性，统一辨证分型，规范疗效标准，充分发挥中医药的优势，提高中医药对DF的诊疗，进一步为中医药治疗DF提供可靠证据。Diabetes foot is one of the chronic complications of Diabetes, and it is also the main reason that causes disability and death. Summarized from the aspects of etiology and pathogenesis, syndrome differentiation type, etc., points out the future expectation of Traditional Chinese Medicine combined with modern scientific research methods, improve syndrome differentiation accuracy and unification curative effect standard, standardization, application of modern science and technology, from the perspective of different and comprehensive research, give full play to advantages of Chinese medicine, improve the diagnosis and treatment of diabetes foot with TCM, provide the reliable evidence for the TCM treatment of diabetes foot

Magnetic helicity evolution during active region emergence and subsequent flare productivity

Aims. Solar active regions (ARs), which are formed by flux emergence, serve as the primary sources of solar eruptions. However, the specific physical mechanism that governs the emergence process and its relationship with flare productivity remains to be thoroughly understood. Methods. We examined 136 emerging ARs, focusing on the evolution of their magnetic helicity and magnetic energy during the emergence phase. Based on the relation between helicity accumulation and magnetic flux evolution, we categorized the samples and investigated their flare productivity. Results. The emerging ARs we studied can be categorized into three types, Type-I, Type-II, and Type-III, and they account for 52.2%, 25%, and 22.8% of the total number in our sample, respectively. Type-I ARs exhibit a synchronous increase in both the magnetic flux and magnetic helicity, while the magnetic helicity in Type-II ARs displays a lag in increasing behind the magnetic flux. Type-III ARs show obvious helicity injections of opposite signs. Significantly, 90% of the flare-productive ARs (flare index > 6) were identified as Type-I ARs, suggesting that this type of AR has a higher potential to become flare productive. In contrast, Type-II and Type-III ARs exhibited a low and moderate likelihood of becoming active, respectively. Our statistical analysis also revealed that Type-I ARs accumulate more magnetic helicity and energy, far beyond what is found in Type-II and Type-III ARs. Moreover, we observed that flare-productive ARs consistently accumulate a significant amount of helicity and energy during their emergence phase. Conclusions. These findings provide valuable insight into the flux emergence phenomena, offering promising possibilities for early-stage predictions of solar eruptions

Crustal Structure of the Indochina Peninsula From Ambient Noise Tomography

The collision between the Indian and Eurasian plates promotes the southeastward extrusion of the Indochina Peninsula while the internal dynamics of its crustal deformation remain enigmatic. Here, we make use of seismic data from 38 stations and employ the ambient noise tomography to construct a 3‐D crustal shear‐wave velocity (Vs) model beneath the Indochina Peninsula. A low‐Vs anomaly is revealed in the mid‐lower crust of the Shan‐Thai Block and probably corresponds to the southern extension of the crustal flow from SE Tibet. Although the Khorat Plateau behaves as a rigid block, the observed low‐Vs anomalies in the lower crust and also below the Moho indicate that the crust may have been partially modified by mantle‐derived melts. The strike‐slip shearing motions of the Red River Fault may have dominantly developed crustal deformation at its western flank where a low‐Vs anomaly is observed at the upper‐middle crust

Graphene Functionalization of Polyrotaxane-Encapsulated PEG-Based PCMs: Fabrication and Applications.

Phase change materials (PCMs) have received much attention regarding the thermal regulation of electronic devices. However, the main limitations of using organic PCMs are the low thermal conductivity and leakage during the phase change process. This work aims to improve these limitations to increase the thermal conductivity of the leakage-proof PCM formed by a polyrotaxane that serves as a support material to encapsulate PEG. For this purpose, different contents of graphene nanoplatelets (GNP) are blended. To facilitate its postindustrial production and to meet ecological standards, the synthesis of this PCM is simple and only using water as a solvent. The PCMs can be thermally processed conveniently by a hot press. Furthermore, the PCMs achieve high enthalpy values (132.9–142.9 J g−1) due to the action of GNPs as thermally conductive fillers. The PCMs exhibited an increase of 60–257% in thermal conductivity values with higher GNP content, and show great shape stability and no leakage during phase change. These improvements solve the main problems of organic PCMs, thus making PLR-PEG-GNP-based materials a good candidate for use as thermal energy storage materials in industrial applications as thermoregulators of solid-state disks or realizing the “shaving peaks and filling valleys” effect for thermoelectric generators.pre-print1654 K

Sodium alginate and Chitosan aided design of form-stable Polyrotaxane based phase change materials with ultra-high latent heat.

We prepared a series of highly porous Polyrotaxane/sodium alginate, and Polyrotaxane/Chitosan foam alloys according to a sustainable pathway by using water as the only solvent. The foam alloys were further used as supporter materials for poly (ethylene glycol) (PEG) encapsulation, to fabricate shape-stable bio-based phase change materials (PCMs). The pore morphology and the internal interface between PEG and foam alloys were characterized by scanning electron microscope (SEM). Due to the good compatibility between foam alloys and PEG, the PCM performed perfect anti-leakage properties. The introduction of sodium alginate or Chitosan ensures the shape stability of the PCMs during the phase transition. The PCMs performed good cycle stability and showed ultra-high latent heat (171.6 J g−1–189.5 J g−1). Finally, we compared the typical indicators of this work with those reported in the literature, and the comparison highlighted that the present PCMs have the significant advantages: high melting enthalpy, convenient preparation and outstanding sustainability. Notably, the work provided a sustainable idea for the design of anti-leakage and shape-stable PEG-based PCMs.pre-print1327 K

Tunable Fano Resonances Based on Two-beam Interference in Microring Resonator

In this paper, a resonant system is demonstrated on silicon-on-insulator wafer to achieve tunable Fano resonances. In this system, the Fano resonance originates from the interference of two beams resonant in the microring resonator. The shapes of the Fano resonances are tunable through controlling the phase difference of the two beams. Both large slope and high extinctionratio (ER) are obtained when the phase difference is 0.5π or 1.5π. Experimental results show that Fano resonances with steep slope and ER over 20 dB are achieved in the whole free spectral range by controlling the microheaters to meet the phase condition

Mantle Transition Zone Discontinuities beneath the Indochina Peninsula: Implications for Slab Subduction and Mantle Upwelling

While the northward indentation of the Indian into Eurasian plates has been intensively investigated, its oblique subduction beneath the Indochina Peninsula (ICP) and the role it played on mantle structure and dynamics remain enigmatic. In this first regional-scale receiver function study of the mantle transition zone (MTZ) discontinuities beneath the ICP and its surrounding areas, we stack ~12,000 receiver functions recorded at 33 stations using a non-plane wave common-conversion-point stacking technique. Systematic spatial variations of MTZ thickness with departures between -21 and +24 km from the globally averaged value are revealed, providing independent evidence for the presence of slab segments in the MTZ beneath the central and a slab window beneath the western ICP. The results also support the existence of broad mantle upwelling adjacent to the eastern edge of the slab segments, which might be responsible for the widespread Cenozoic volcanisms and pervasively observed upper mantle low velocities in the area