高エネルギー密度全固体フッ化物電池用鉄系酸フッ化物正極の開発

京都大学新制・課程博士博士(人間・環境学)甲第24710号人博第1083号新制||人||253(附属図書館)2022||人博||1083(吉田南総合図書館)京都大学大学院人間・環境学研究科相関環境学専攻(主査)教授 内本 喜晴, 教授 田部 勢津久, 教授 吉田 鉄平, 教授 雨澤 浩史学位規則第4条第1項該当Doctor of Human and Environmental StudiesKyoto UniversityDFA

The Effect of Resveratrol on Swarming Differentiation and the Expression of Some Virulence Factors in Proteus vulgaris

Resveratrol (3,5,4'-trihydroxy-trans-stilbene) is a stilbenoid, a type of natural phenol, and a phytoalexin with anti-inflammatory and antioxidant activities. It is produced naturally by several plants especially the roots of the Japanese Knotweed when under attack by pathogens such as bacteria or fungi. In this study we have verified that resveratrol has activity against Proteus vulgaris, an important pathogen infecting the urinary tract by investigating its effect on swarming and some virulence factor expression(haemolysin and urease).Swarming inhibition was determined on Luria Bertani agar with and without resveratrol and then bacteria was harvested to assay cell length and the production of haemolysin and urease.  Resveratrol significantly inhibited swarming and virulence factor expression but its effect on growth rate was not significant. Keywords: Resveratrol, Proteus vulgaris, phytoalexin, haemolysin, urease

The Coordination of Centromere Replication, Spindle Formation, and Kinetochore–Microtubule Interaction in Budding Yeast

The kinetochore is a protein complex that assembles on centromeric DNA to mediate chromosome–microtubule interaction. Most eukaryotic cells form the spindle and establish kinetochore–microtubule interaction during mitosis, but budding yeast cells finish these processes in S-phase. It has long been noticed that the S-phase spindle in budding yeast is shorter than that in metaphase, but the biological significance of this short S-phase spindle structure remains unclear. We addressed this issue by using ask1-3, a temperature-sensitive kinetochore mutant that exhibits partially elongated spindles at permissive temperature in the presence of hydroxyurea (HU), a DNA synthesis inhibitor. After exposure to and removal of HU, ask1-3 cells show a delayed anaphase entry. This delay depends on the spindle checkpoint, which monitors kinetochore–microtubule interaction defects. Overproduction of microtubule-associated protein Ase1 or Cin8 also induces spindle elongation in HU-arrested cells. The spindle checkpoint-dependent anaphase entry delay is also observed after ASE1 or CIN8 overexpression in HU-arrested cells. Therefore, the shorter spindle in S-phase cells is likely to facilitate proper chromosome–microtubule interaction

Characteristic classes of vector bundles over CP(j)timesHP(k) CP(j)times HP(k) and involutions fixing CP(2m+1)timesHP(k) CP(2m+1)times HP(k)

In this paper, we determine the total Stiefel-Whitney classes of vector bundles over the product of the complex projective space $CP(j)$ with the quaternionic projective space $HP(k)$. Moreover, we show that every involution fixing $CP(2m+1)times HP(k)$ bounds

Genetic and clinical assessment of 2009 pandemic influenza in southern China

Introduction: South China has a proven role in the global epidemiology of previous influenza outbreaks due to its dual seasonal pattern. We present the virologic, genetic and clinical characterization of pandemic H1N1 influenza infection (pH1N1) in Shantou and Nanchang, cities in southern China, during the second wave of the 2009-2010 pandemic. Methodology: Nasopharyngeal swabs were collected from 165 individuals with influenza-like illness (ILI) who presented to the hospitals in Shantou and Nanchang. Laboratory diagnosis and characterization was performed by real-time PCR, virus isolation in embryonated chicken eggs, and sequencing. Results: pH1N1 activity was sustained in three different temporal patterns throughout the study period. The overall positivity rate of pH1N1 was 50% with major distribution among young adults between the ages of 13 and 30 years. High fever, cough, expectoration, chest pain, myalgia, nasal discharge and efficient viral replication were observed as major clinical markers whereas a substantial number of afebrile cases (17%) was also observed. Rate of hospitalization and disease severity (39%) and recovery (100%) were also high within the region. Furthermore, severe complications were likely to develop in young adults upon pH1N1 infection. Genetic characterization of the HA and NA genes of pH1N1 strains exhibited homogenous spread of pH1N1 strains with 99% identity with prototypic strains; however, minor unique mutations were also observed in the HA gene. Conclusion: The study illustrates the detailed characteristics of 2009 influenza pandemic in southern parts of China that might help to strategize preparedness for future pandemics and subsequent influenza seasons.</br

Analysis and treatment of jitter for 300MW steam turbine high-pressure control valve

The high-pressure control valve of Weifang power generation Co. LTD unit one turbine happens to jitter during operation, especially in the low opening action, the jitter is more frequent. This situation is serious for the safety and stability of generating unit. This paper analyzes the cause of the high-pressure control valve jitter and formulates effective reconstruction plans. After the reform of the high-pressure control valve, it can maintain stable and normal regulation to ensure the safety and stability of the generating unit

Experimental research on damage identification of topping dangerous rock structural surface based on dynamic characteristic parameters

Rock block tilting is one of the most common types of dangerous rock block failures with no clear indicator of displacement prior to failure. Existing stability evaluation methods remain limited in their ability to constrain the non-penetrating section area, which is closely related to rock stability, and stability evaluations are therefore associated with large uncertainties. The dynamic characteristic parameters of toppling dangerous rock are closely related to structural plane strength. Under vibration loading, rainfall, and/or excavation unloading conditions, the structural plane becomes damaged and the dynamic characteristic parameters change. In this study, we present a dynamic characteristic model of rock tilting and identify the quantitative and qualitative relationship between dynamic characteristic parameters and the bonded area of the structural plane. The model accuracy is verified by experiments. The experimental results show that the damping ratio decreases linearly with structural plane damage, whereas the maximum vibration speed and particle trajectory increases nonlinearly and the natural vibration frequency decreases nonlinearly. The dynamic characteristic model and experimental results can be used to evaluate the degree of structural surface damage of toppling dangerous rock

Properties of Composite Electrodes for All-solid-state Fluoride-ion Secondary Batteries Processed by High-pressure Torsion

All-solid-state fluoride-ion batteries (FIBs) using metal/metal fluorides are expected to be the next generation of storage batteries because they exhibit high volumetric energy densities by utilizing multielectron reactions, compared to the current lithium-ion batteries. However, method of fabricating a composite electrode for all-solid-state fluoride-ion batteries has not yet been established. A fabrication method for a composite electrode that disperses the active material and solid electrolyte is required. To approach this problem, in this study, we employed a high-pressure torsion (HPT) method, in which an active material, solid electrolyte, and conductive agent can be mixed with size reduction, as a new process and prepared Cu (active material)/PbSnF₄ (solid electrolyte)/acetylene black (conductive agent) cathode composites. The crystalline sizes of Cu and PbSnF₄ were significantly reduced. The apparent grain boundary resistance was also reduced owing to the more homogeneous distribution in the cathode composites after HPT processing. These structural and morphological changes led to high electrochemical performances, compared to a cathode composite without HPT