Recurrent venous thromboembolism after discontinuation of rivaroxaban therapy in a patient with antiphospholipid syndrome

A Antiphospholipid syndrome (APS) is a systemic autoimmune disease characterized by thrombembolic events including thromboembolism (VTE) in association with the presence of antiphospholipid antibodies. The standard treatment of VTE historically consists of anticoagulation therapy with warfarin, a vitamin K antagonist. Recently, direct oral anticoagulants, including rivaroxaban have become available for the treatment of VTE. However, the choice of anticoagulant, and the duration of anticoagulation in patients with APS has not been determined yet due to lack of evidence. Here, we report a case of recurrent venous thrombosis after discontinuation of rivaroxaban therapy and avoiding sedentary life style in a patient with APS. We suggest that indefinite anticoagulation therapy might be needed even in low risk APS cases

Hemispherical confocal imaging using turtleback reflector

We propose a new imaging method called hemispherical confocal imaging to clearly visualize a particular depth in a 3-D scene. The key optical component is a turtleback reflector which is a specially designed polyhedral mirror. By combining the turtleback reflector with a coaxial pair of a camera and a projector, many virtual cameras and projectors are produced on a hemisphere with uniform density to synthesize a hemispherical aperture. In such an optical device, high frequency illumination can be focused at a particular depth in the scene to visualize only the depth with descattering. Then, the observed views are factorized into masking, attenuation, and texture terms to enhance visualization when obstacles are present. Experiments using a prototype system show that only the particular depth is effectively illuminated and hazes by scattering and attenuation can be recovered even when obstacles exist.Microsoft ResearchJapan Society for the Promotion of Science (Grants-in-Aid For Scientific Research 21680017)Japan Society for the Promotion of Science (Grants-in-Aid For Scientific Research 21650038

Dewatering of inorganic sludge using dual ionic thermosensitive polymers

The dewatering of inorganic sludge by a novel method based on the hydrophilic/hydrophobic transition of ionic thermosensitive polymers was investigated. As an inorganic sludge, the drinking water treatment sludge was used. Cationic thermosensitive polymers, poly(NIPAM-co-DMAPAA), which were synthesized by copolymerizing N,N-dimethylaminopropylacrylamide (DMAPAA) as the cationic component with N-isopropylacrylamide (NIPAM) as the thermosensitive component, were effective in dewatering the sludge. When the dewatering was performed at room temperature, the optimum polymer dosage for the dewatering rate was observed similar to the conventional hydrophilic polymeric flocculants. On the other hand, when the dewatering was carried out above the lower critical solution temperature (LCST) of poly(NIPAM-co-DMAPAA), the dewatering rate increased remarkably as the polymer dosage increased. Such high dewatering rates can be attributed to the hydrophobic interaction among the thermosensitive polymer molecules adsorbed on the sludge. However, the LCST of poly(NIPAM-co-DMAPAA) increased considerably as the DMAPAA content increased. In order to solve this problem, the use of dual ionic thermosensitive polymers was investigated. By using the anionic thermosensitive polymer, poly (NIPAM-co-AAC), which was synthesized by copolymerizing acrylic acid (MC) with NIPAM, in combination with cationic poly(NIPAM-co-DMAPAA), the dewatering rate was remarkably increased at relatively low temperatures. This increase was attributed to the formation of a polymer complex that decreased the LCST of the polymer molecules adsorbed on the sludge

Light Transport Refocusing for Unknown Scattering Medium

2014 22nd International Conference on Pattern Recognition,Stockholm, Sweden,24-28 Aug. 2014In this paper we propose a new light transport refocusing method for depth estimation as well as for investigation inside scattering media with unknown scattering properties. Propagated visible light rays through scattering media are utilized in our proposed refocusing method. We use 2D light source to illuminate the scattering media and 2D image sensor for capturing transported rays. The proposed method that uses 4D light transport can clearly visualize shallow depth, as well as deep depth plane of the medium. We apply our light transport refocusing method for depth estimation using conventional depth-from-focus method and for clear visualization by descattering the light rays passing through the medium. To evaluate the effectiveness we have done experiments using acrylic and milk-water type scattering medium in various optical and geometrical conditions. Finally, we show up the results of depth estimation and clear visualization, as well as with numeric evaluation

Osteolytic bone lymphoma

Primary non-Hodgkin bone lymphoma (PBL) can involve solitary or multiple destructive bone lesions such as those of the femur or pelvis humerus, and some cases have osteolytic lesions. PBL is a rare disease in adults. Thus, PBL is rarely considered a differential diagnosis of the osteolytic tumor. In addition, PBL can be underdiagnosed because patients do not experience symptoms or show objective abnormalities in the early stage. Here, we reported an elderly patient with PBL in multiple bones, including the cranial and femoral bones that were fractured due to falling

イショセイ シボウ ト 2ガタ トウニョウビョウ シンゾウ ケッカンビョウ

There is evidence supporting the notion that excess abdominal fat is predictive of insulin resistance and the presence of related metabolic abnormalities currently referred to as the metabolic syndrome (MetS). Despite the fact that abdominal obesity is a highly prevalent feature of MetS, the mechanisms by which abdominal obesity is causally related to MetS are not fully elucidated. Besides visceral fat accumulation, ectopic lipid deposition, especially in the liver and skeletal muscle, has been implicated in the pathophysiology of diabetes, insulin resistance and obesity-related disorders. In addition, ectopic fat deposition play a critical role in the heart components such as (1) circulatory and locally recruited fat, (2) intra-and extra-myocellular fat, (3) perivascular fat, and (4) pericardial fat. In this review, the contribution of ectopic lipid deposition to global cardiometabolic risk is discussed via possible mechanisms including adipocytokine, insulin resistance and lipotoxicity