Satellite estimates of wide-range suspended sediment concentrations in Changjiang (Yangtze) estuary using MERIS data

The Changjiang (Yangtze) estuarine and coastal waters are characterized by suspended sediments over a wide range of concentrations from 20 to 2,500 mg l-1. Suspended sediment plays important roles in the estuarine and coastal system and environment. Previous algorithms for satellite estimates of suspended sediment concentration (SSC) showed a great limitation in that only low to moderate concentrations (up to 50 mg l-1) could be reliably estimated. In this study, we developed a semi-empirical radiative transfer (SERT) model with physically based empirical coefficients to estimate SSC from MERIS data over turbid waters with a much wider range of SSC. The model was based on the Kubelka–Munk two-stream approximation of radiative transfer theory and calibrated using datasets from in situ measurements and outdoor controlled tank experiments. The results show that the sensitivity and saturation level of remote-sensing reflectance to SSC are dependent on wavelengths and SSC levels. Therefore, the SERT model, coupled with a multi-conditional algorithm scheme adapted to satellite retrieval of wide-range SSC, was proposed. Results suggest that this method is more effective and accurate in the estimation of SSC over turbid water

Cross-textual reconceptualisation of the deictic space of “victory” in political discourse: Donald Trump versus Joseph Biden

The present study propounds the notion-complex of cross-textual reconceptualisation as a cognitive-linguistic output of applying Paul Chilton’s (2013, 2014, 2017) model of Deictic Space Theory (DST) to textual practices drawn from the broad domain of political discourse. The DST model has operated methodologically towards conducting a cognitively oriented political discourse analysis of the two victory speeches produced by Donald Trump and Joseph Biden during the 2020 election for US presidency. As a geometric model, DST has been applied to the two speeches in a way that demonstrated the deictic spatial construction of victory in relation to Trump and Biden as the now-here-real speakers on the three axes of discourse referents, time, and epistemic modality. The data analysis has revealed four significant instantiations of cross-textual reconceptualisation made by Biden of Trump’s deictic space of victory as a contested concept: (i) a “clear” and “convincing” victory, (ii) a peripersonal real victory, (iii) Trump and his voters, and (iv) a now shift from a past Democrat to a future President. All four instantiations have proved the hypothesis that the DST model, while revealing the deictic-spatial conceptualisations of “victory” constituted by each speaker in his speech, may further be extended to disentangle the interesting aspect of how one and the same concept could be reconceptualised across two textual practices produced by speakers with ideologically opposed perspectives.

Potential of using remote sensing techniques for global assessment of water footprint of crops

Remote sensing has long been a useful tool in global applications, since it provides physically-based, worldwide, and consistent spatial information. This paper discusses the potential of using these techniques in the research field of water management, particularly for ‘Water Footprint’ (WF) studies. The WF of a crop is defined as the volume of water consumed for its production, where green and blue WF stand for rain and irrigation water usage, respectively. In this paper evapotranspiration, precipitation, water storage, runoff and land use are identified as key variables to potentially be estimated by remote sensing and used for WF assessment. A mass water balance is proposed to calculate the volume of irrigation applied, and green and blue WF are obtained from the green and blue evapotranspiration components. The source of remote sensing data is described and a simplified example is included, which uses evapotranspiration estimates from the geostationary satellite Meteosat 9 and precipitation estimates obtained with the Climatic Prediction Center Morphing Technique (CMORPH). The combination of data in this approach brings several limitations with respect to discrepancies in spatial and temporal resolution and data availability, which are discussed in detail. This work provides new tools for global WF assessment and represents an innovative approach to global irrigation mapping, enabling the estimation of green and blue water use

Nature of urban interventions in changing the old center of a globalizing Doha

Doha, Qatar is continuously positioning itself at the forefront of international urbanism with different qualities of expression in terms of economy, culture, and global outlook, and is characterized by fast-tracked urban development process with large-scale urban interventions in the old center. Although the unprecedented urban growth of this city continues to be a subject of discussion, little attention has been given to investigate the new interventions and the resulting effects they have on the old center. This study aims to examine three important urban interventions, namely, the Museum of Islamic Art, the reconstruction of the traditional market called Souq Waqif, and the Msheireb urban regeneration project. It examines local and global issues, universal standard practices, and traditional knowledge. This study employs a descriptive analysis of these interventions to explore the impact of change in the old center, exemplified by socio-spatial and typo-morphological aspects. Reference is made to a number of empirical studies, including behavioral mapping, GIS population statistics, and analysis of historical maps. Results analytically narrate the reactions of these interventions to the possibility of simultaneously adopting universal practices with local knowledge, and whether prioritizing local influences would represent narrow-mindedness in shaping the city

Analysis of long-term terrestrial water storage variations in the Yangtze River basin

In this study, we analyze 32 yr of terrestrial water storage (TWS) data obtained from the Interim Reanalysis Data (ERA-Interim) and Noah model from the Global Land Data Assimilation System (GLDAS-Noah) for the period 1979 to 2010. The accuracy of these datasets is validated using 26 yr (1979–2004) of runoff data from the Yichang gauging station and comparing them with 32 yr of independent precipitation data obtained from the Global Precipitation Climatology Centre Full Data Reanalysis Version 6 (GPCC) and NOAA's PRECipitation REConstruction over Land (PREC/L). Spatial and temporal analysis of the TWS data shows that TWS in the Yangtze River basin has decreased significantly since the year 1998. The driest period in the basin occurred between 2005 and 2010, and particularly in the middle and lower Yangtze reaches. The TWS figures changed abruptly to persistently high negative anomalies in the middle and lower Yangtze reaches in 2004. The year 2006 is identified as major inflection point, at which the system starts exhibiting a persistent decrease in TWS. Comparing these TWS trends with independent precipitation datasets shows that the recent decrease in TWS can be attributed mainly to a decrease in the amount of precipitation. Our findings are based on observations and modeling datasets and confirm previous results based on gauging station datasets

A study of annexin-V labeled-lymphocytes apoptosis in pediatric-onset systemic lupus erythematosus in comparison to juvenile rheumatoid arthritis

Background: In systemic lupus erythematosus (SLE), which is the prototype of autoimmune diseases, the autoimmune process seems to be antigen driven. Apoptosis is responsible for eliminating cells from the immune system that are autoreactive, and defects in apoptosis may contribute to autoimmune diseases such as SLE and juvenile rheumatoid arthritis (JRA). Objective: This work is aimed to study the apoptotic peripheral blood lymphocytes in patients with pediatric- onset SLE, to trace its correlations, if any, with the disease activity and clinical presentation, and to compare the apoptotic process to that in JRA, as an example of another rheumatologic disorder. Methods: The study was conducted on 32 patients with pediatric- onset SLE; their ages ranged between 5 and 25 years (mean + SD = 15.5 + 4.4). In addition to various laboratory investigations needed for diagnosis, assessment of different system involvement as well as disease activity, the percentage of early circulating apoptotic lymphocytes was measured by flowcytometry using Annexin –V. The results were compared to that of 20 age and sex matched clinically healthy children and adolescents as well as 10 JRA patients. Results: The percentage of circulating early apoptotic lymphocytes was significantly higher in SLE patients (mean ± SD = 7.02 ± 7.29 %) and JRA patients (mean ± SD=5.91± 6.00 %) as compared to healthy controls (mean ± SD = 1.89 ± 2.21 %; p=0.0003 and 0.023, respectively). The levels of apoptotic lymphocytes seemed higher in SLE patients than in JRA patients but the difference was statistically insignificant (p=0.58). There was no correlation between the percentage of circulating apoptotic lymphocytes and the disease activity markers (SLEDAI and ESR), different system involvement and the dose or duration of corticosteroids therapy. Conclusion: The general increase of circulating apoptotic lymphocytes seen in SLE patients may not be specific to SLE and could be seen with other autoimmune diseases. It seems that disturbance in the apoptotic process contributes more to the phenomenon of autoantigenicity rather than the prediction of the disease clinical activity or specific organ involvement.Keywords: SLE, apoptosis, annexin V, autoimmune diseases, JRA, PediatricEgypt J Pediatr Allergy Immunol 2003; 1(2): 118-2

Spitzer-IRAC survey of molecular jets in Vela-D

We present a survey of H2 jets from young protostars in the Vela-D molecular cloud (VMR-D), based on Spitzer -IRAC data between 3.6 and 8.0 micron. Our search has led to the identification of 15 jets and about 70 well aligned knots within 1.2 squared degree. We compare the IRAC maps with observations of the H2 1-0 S(1) line at 2.12 micron, with a Spitzer-MIPS map at 24 and 70 micron, and with a map of the dust continuum emission at 1.2 mm. We find a association between molecular jets and dust peaks. The jet candidate exciting sources have been searched for in the published catalog of the Young Stellar Objects of VMR-D. We selected all the sources of Class II or earlier which are located close to the jet center and aligned with it.The association between jet and exciting source was validated by estimating the differential extinction between the jet opposite lobes. We are able to find a best-candidate exciting source in all but two jets. Four exciting sources are not (or very barely) observed at wavelengths shorter than 24 micron, suggesting they are very young protostars. Three of them are also associated with the most compact jets. The exciting source Spectral Energy Distributions have been modeled by means of the photometric data between 1.2 micron and 1.2 mm. From SEDs fits we derive the main source parameters, which indicate that most of them are low-mass protostars. A significant correlation is found between the projected jet length and the [24] - [70] color, which is consistent with an evolutionary scenario according to which shorter jets are associated with younger sources. A rough correlation is found between IRAC line cooling and exciting source bolometric luminosity, in agreement with the previous literature. The emerging trend suggests that mass loss and mass accretion are tightly related phenomena and that both decrease with time.Comment: Accepted by The Astrophysical Journa

The Effect of Tamoxifen and Raloxifene on Estrogen Metabolism and Endometrial Cancer Risk

Selective estrogen receptor modulators (SERMs) demonstrate differential endometrial cancer (EC) risk. While tamoxifen (TAM) use increases the risk of endometrial hyperplasia and malignancy, raloxifene (RAL) has neutral effects on the uterus. How TAM increases the risk of EC and why TAM and RAL differentially modulate the risk for EC, however, remain elusive. Here, we tested the hypothesis that TAM increases the risk for EC, at least in part, by enhancing the local estrogen biosynthesis and directing estrogen metabolism towards the formation of genotoxic and hormonally active estrogen metabolites. In addition, the differential effects of TAM and RAL in EC risk are attributed to their differential effect on estrogen metabolism/metabolites. The endometrial cancer cell line (Ishikawa cells) and the nonmalignant immortalized human endometrial glandular cell line (EM1) were used for the study. The profile of estrogen/estrogen metabolites (EM), depurinating estrogen-DNA adducts, and the expression of estrogen-metabolizing enzymes in cells treated with 17β-estradiol (E2) alone or in combination with TAM or RAL were investigated using high performance liquid chromatography-electrospray ionization-tandem mass spectrometry (HPLC-ESI-MS(2)), ultraperformance liquid chromatography/tandem mass spectrometry (UPLC-MS/MS), and Western blot analysis, respectively. TAM significantly increased the total EM and enhanced the formation of hormonally active and carcinogenic estrogen metabolites, 4-hydroxestrone (4-OHE1) and 16α-hydroxyestrone, with concomitant reduction in the formation of antiestrogenic and anticarcinogenic 2-hydroxyestradiol and 2-methoxyestradiol. Furthermore, TAM increased the formation of depurinating estrogen-DNA adducts 4-OHE1 [2]-1-N7Guanine and 4-OHE1 [2]-1-N3 Adenine. TAM-induced alteration in EM and depurinating DNA adduct formation is associated with altered expression of estrogen metabolizing enzymes CYP1A1, CYP1B1, COMT, NQO1, and SF-1 as revealed by Western blot analysis. In contrast to TAM, RAL has minimal effect on EM, estrogen-DNA adduct formation, or estrogen-metabolizing enzymes expression. These data show that TAM perturbs the balance of estrogen-metabolizing enzymes and alters the disposition of estrogen metabolites, which can explain, at least in part, the mechanism for TAM-induced EC. These results also implicate the differential effect of TAM and RAL on estrogen metabolism/metabolites as a potential mechanism for their disparate effects on the endometrium

Development of Y-Ba-Cu-O Superconductors for Magnetic Bearings

The material requirements, material manufacturing and magnetic properties that are relevant to fabrication of High Temperature Superconductor (HTS) magnetic bearings have been discussed. It is found that the seeded-melt-texturing method can be used to fabricate the single domain material that is required to achieve the best magnetic properties. Trapped-field mapping has been used as a non-destructive tool to determine the single-domain nature of the HTS material and quantity of the HTS disks. Both the trapped field and the levitation force of the Y-Ba-Cu-O disks are found to be strongly sensitive to the oxygen content