Estação de monitoramento de parâmetros ambientais com relógio CMOS.

Uma estação meteorológica ou climatológica é um dispositivo que coleta dados para análise do tempo meteorológico. Encontram-se equipadas com instrumentos (ou sensores eletrônicos) de medição e registro das variáveis meteorológico-climáticas. Os seus dados são utilizados para a previsão do tempo e para a caracterização do clima. A difusão sistemas de hardware e software open source tornou a obtenção de dados atmosféricos algo corriqueiro e usual, tarefa antes restrita aos meteorologistas. Em nossos dias, por meio de softwares e hardware livres integram-se os dados coletados, permitindo a sua apresentação e análise

Magneto-Optical Studies of Exciton Effects in Layer-Type Semiconductors

Both experimental and theoretical works were performed with particular reference to a layer-type semiconductor, GaSe, for a coherent treatment of the exciton-like and the oscillatory Landau-like spectra appearing in a form of their combination in semiconductors in magnetic fields. The interband magneto-absorption and the Faraday rotation were measured in pulsed magnetic fields up to ～200 kOe at low temperatures. The theoretical analysis was based mainly on the exact solution for an extremely anisotropic semiconductor in the magnetic field of arbitrary intensity. The exciton effects are discussed in terms of the energy spectrum, the spectral intensity, and the spectral width by the use of the band parameters deduced from the experimental results

Blog de compartilhamento de informação para projetos de 'internet das coisas'.

A escolha deste meio para divulgação deve-se ao fato de haver muitos modelos de software e hardware open source, que facilitam a inserção de conteúdo e a personalização de páginas e endereços, além de possibilitar o compartilhamento de não apenas textos, mais também fotos, vídeos, arquivos, entre outros tipos de mídia, dispensando o conhecimento em linguagens computacionais específicas utilizadas para publicar conteúdos na internet. Atualmente, a presença cada vez mais forte dos dispositivos eletrônicos em nosso dia-a-dia e a internet possibilita a comunicação entre estes dispositivos que armazenam e identificam várias informações através de sensores e softwares. A interação entre os dispositivos acontece principalmente através de sistemas interligados a uma mesma rede. Esse fenômeno está cada vez mais presente, sendo agregado a sensores e outros periféricos, criando uma inteligência própria de cada objeto, aumentando seu poder de processamento das informações, chamado de ‘internet das coisas’ (Internet of Things, do inglês)

Inverse Correlation between Serum Levels of Selenoprotein P and Adiponectin in Patients with Type 2 Diabetes

Background: We recently identified selenoprotein P (SeP) as a liver-derived secretory protein that causes insulin resistance in the liver and skeletal muscle; however, it is unknown whether and, if so, how SeP acts on adipose tissue. The present study tested the hypothesis that SeP is related to hypoadiponectinemia in patients with type 2 diabetes. Methodology/Principal Findings: We compared serum levels of SeP with those of adiponectin and other clinical parameters in 36 patients with type 2 diabetes. We also measured levels of blood adiponectin in SeP knockout mice. Circulating SeP levels were positively correlated with fasting plasma glucose (r = 0.35, P = 0.037) and negatively associated with both total and high-molecular adiponectin in patients with type 2 diabetes (r = 20.355, P = 0.034; r = 20.367, P = 0.028). SeP was a predictor of both total and high-molecular adiponectin, independently of age, body weight, and quantitative insulin sensitivity index (b = 20.343, P = 0.022; b = 20.357, P = 0.017). SeP knockout mice exhibited an increase in blood adiponectin levels when fed regular chow or a high sucrose, high fat diet. Conclusions/Significance: These results suggest that overproduction of liver-derived secretory protein SeP is connected with hypoadiponectinemia in patients with type 2 diabetes

The role of anti-aquaporin 4 antibody in the conversion of acute brainstem syndrome to neuromyelitis optica

Background: Acute brainstem syndrome (ABS) may herald multiple sclerosis (MS), neuromyelitis optica (NMO), or occur as an isolated syndrome. The aquaporin 4 (AQP4)-specific serum autoantibody, NMO-IgG, is a biomarker for NMO. However, the role of anti-AQP4 antibody in the conversion of ABS to NMO is unclear. Methods: Thirty-one patients with first-event ABS were divided into two groups according to the presence of anti-AQP4 antibodies, their clinical features and outcomes were retrospectively analyzed. Results: Fourteen of 31 patients (45.16 %) were seropositive for NMO-IgG. The 71.43 % of anti-AQP4 (+) ABS patients converted to NMO, while only 11.76 % of anti-AQP4 (-) ABS patients progressed to NMO. Anti-AQP4 (+) ABS patients demonstrated a higher IgG index (0.68 ± 0.43 vs 0.42 ± 0.13, p < 0.01) and Kurtzke Expanded Disability Status Scale (4.64 ± 0.93 vs 2.56 ± 0.81, p < 0.01) than anti-AQP4 (-) ABS patients. Area postrema clinical brainstem symptoms occurred more frequently in anti-AQP4 (+) ABS patients than those in anti-AQP4 (-) ABS patients (71.43 % vs 17.65 %, p = 0.004). In examination of magnetic resonance imaging (MRI), the 78.57 % of anti-AQP4 (+) ABS patients had medulla-predominant involvements in the sagittal view and dorsal-predominant involvements in the axial view. Conclusions: ABS represents an inaugural or limited form of NMO in a high proportion of anti-AQP4 (+) patients

Outcome prediction models in AQP4-IgG positive neuromyelitis optica spectrum disorders

Pathogenic antibodies targeting the aquaporin-4 water channel on astrocytes are associated with relapsing inflammatory neuromyelitis optica spectrum disorders. The clinical phenotype is characterized by recurrent episodes of optic neuritis, longitudinally extensive transverse myelitis, area postrema attacks and less common brainstem and cerebral events. Patients often develop major residual disability from these attacks, so early diagnosis and initiation of attackpreventing medications is important. Accurate prediction of relapse would assist physicians in counselling patients, planning treatment and designing clinical trials. We used a large multicentre dataset of 441 patients from the UK, USA, Japan and Martinique who collectively experienced 1976 attacks, and applied sophisticated mathematical modelling to predict likelihood of relapse and disability at different time points. We found that Japanese patients had a lower risk of subsequent attacks except for brainstem and cerebral events, with an overall relative relapse risk of 0.681 (P = 0.001) compared to Caucasians and African patients, who had a higher likelihood of cerebral attacks, with a relative relapse risk of 3.309 (P = 0.009) compared to Caucasians. Female patients had a higher chance of relapse than male patients (P = 0.009), and patients with younger age of onset were more likely to have optic neuritis relapses (P < 0.001). Immunosuppressant drugs reduced and multiple sclerosis disease-modifying agents increased the likelihood of relapse (P < 0.001). Patients with optic neuritis at onset were more likely to develop blindness (P < 0.001), and those with older age of onset were more likely to develop ambulatory disability. Only 25% of long-term disability was related to initial onset attack, indicating the importance of early attack prevention. With respect to selection of patients for clinical trial design, there would be no gain in power by selecting recent onset patients and only a small gain by selecting patients with recent high disease activity. We provide risk estimates of relapse and disability for patients diagnosed and treated with immunosuppressive treatments over the subsequent 2, 3, 5 and 10 years according to type of attack at onset or the first 2-year course, ethnicity, sex and onset age. This study supports significant effects of onset age, onset phenotype and ethnicity on neuromyelitis optica spectrum disorders outcomes. Our results suggest that powering clinical treatment trials based upon relapse activity in the preceding 2 years may offer little benefit in the way of attack risk yet severely hamper clinical trial success