33 research outputs found

    Erratum to: 36th International Symposium on Intensive Care and Emergency Medicine

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    [This corrects the article DOI: 10.1186/s13054-016-1208-6.]

    Dexmedetomidine modifies uterine contractions in pregnancy terms of rats

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    PubMedID: 23716894Objectives: The present study was aimed at determining the effective doses of Dexmedetomidine (Dex) involved in amplitude of contraction-force and frequency of uterine rings in pregnancy terms of rats. All experiments involving animal subjects were carried out with the approval of animal care and use Ethical Committee of Cukurova University. Experiments were performed on female Albino-Wistar rats (200-260 g; n = 40). Materials and Methods: Uterine rings from pregnant rats were placed in organ bath with Krebs and calcium ion (Ca 2+ )-free solutions to record and exposed to serially increasing log10 concentrations of Dex. Results: In Krebs solution, while Dex caused an increase in the spontaneous contraction-forces in all pregnancy terms of rats in a significant dose-dependent manner, it led to a decrease in contraction-frequency in late-pregnancy term of rats. In Ca2+ -free, the spontaneous contraction-force decreased in late-pregnancy term and increased in early and middle-pregnancy terms. In addition, while Dex increased the contraction-frequency in early and middle-pregnancy terms, it decreased in late-pregnancy term in a dose-dependent manner. Statistical Analysis Used: The data were subjected to one-way analysis of variance. Repeated measures were employed for comparison of several group means through the Tukey post-hoc test (SPSS 10.00 Inc., Chicago, Ill, USA). P < 0.05 was considered statistically significant. Conclusions: This study suggested that Dex might differently alter the spontaneous contraction-forces and contraction-frequencies of uterine rings in all pregnancy terms of rats in Krebs and Ca 2+ -free solutions

    Dimensional approach to obsessive-compulsive disorder: Dimensional obsessive-compulsive scale with Turkish psychometric properties

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    Objective: The Dimensional Obsessive Compulsive Scale (DOCS) is a measurement tool that examines the severity of thematically distinct symptom domains of obsessive compulsive disorder (OCD). In this study we assess psychometric properties of the Turkish version of DOCS. Methods: Ninety-six patients who presented consecutively to the Dişkapi Yildirim Beyazit Teaching and Research Hospital outpatient unit and who were diagnosed with OCD according to the DSM-IV-TR criteria were enrolled in the study. The DOCS, Yale-Brown Obsessive Compulsive Scale (YBOCS), and Padua Inventory (PI) were completed by the participants. Internal consistency was estimated using Cronbach's Alpha values and item-total correlations. Principal component analyses with Varimax rotation were used to assess latent factor structure . Results: Explanatory Factor Analyses (EFA) revealed a 4-factor solution for the DOCS. Chronbach's alpha values for the whole scale, "contamination" sub-scale, "responsibility" sub-scale, "unacceptable thoughts", and "symmetry" sub-scales were 0.874, 0.932, 0.933, 0.948, 0.921, respectively. There was a high correlation between It has been determined that there is high correlations between both total scores and sub-scales scores of DOCS, YBOCS and PI. Conclusions: Internal consistencies were high good for the total scale and very high perfect for the sub-scales. The factor structure and the contents of the factors were perfectly in line with the original scale (i.e. 4 factor). Positive correlations between DOCS, its sub-scales, and similar OCD scales suggest that the DOCS accurately measures the structures it claims to assess. Thus the DOCS Turkish version can measure dimensional obsessive compulsive symptoms among the Turkish speaking OCD population. © 2018 Turkish Association of Nervous and Mental Health

    Development of nematode resistant pure pepper lines via anther culture method

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    This study was carried out in the laboratories and greenhouses of Çukurova University, Alata Horticultural Research Institute and a seed company between 2015 and 2016 to obtain nematode resistant pure pepper lines. The pure lines were obtained from F1 plants via anther culture method. F1 plants were obtained via crossing of three nematode resistant pepper genitors in F6 level (N-269: green -N gen, N-8: green-N gen and N-6: bell-N gen) which were obtained from the studies carried out at the Alata Horticultural Research Institute with breeding pepper lines of a seed company selected in terms of high fruit quality and desired agronomic characters in F3 level (5 green, 5 bell, 5 charleston and 5 capia). Murashige and Skoog (MS) nutrient medium contained 30 g L-1 sucrose, 0.25% activated charcoal, 15 mg L-1 silver nitrate (AgNO3), 4 mg L-1 naphthaleneacetic acid (NAA) and 0.5 mg L-1 6-benzylaminopurine (BAP) was used. The cultivated anthers were transferred hormone-free MS nutrient medium after 35 days. As a result of the study; it was observed that different parameters were changed according to genotypes. The highest embryo yield was obtained from the genotype numbered Z-tad 87 (nematode resistance × bell hybrid). Among crossing between nematode resistance and different pepper types; bell pepper type gave the highest embryo yield and this was followed by capia, charleston, and green types. The highest rate of embryos produced plants was observed in green pepper type. The highest haploid plant percentage was observed in capia pepper type and this was followed by charleston. As a result, all genotypes tested reacted to anther culture and the number of embryo and haploid plants obtained were varied. In the study, three homozygote pure lines contained Me1, Me3, N and Me7 resistance genes were recorded. Also, one homozygote pure lines contained Me1 was noted. These nematode resistant genotypes obtained can also be used in breeding studies. © 2019 International Society for Horticultural Science. All rights reserved.Ministry of Science, Technology and Space Türkiye Bilimsel ve Teknolojik Araştirma KurumuThe authors would like to thank the Republic of Turkey Ministry of Science, Industry, and Technology (Project Code: ? ? ? ?.STZ. ? ? ? ?) and the Scientific and Technological Research Council of Turkey (TUBITAK) for supporting this research

    VAN GÖLÜ (EDREMİT KÖRFEZİ) KUVATERNER ÇÖKELLERİNDE TEKTONİK DEFORMASYONLAR, DOĞU ANADOLU, TÜRKİYE

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    3 Ekim 2011 Van Depremi (Mw: 7,2) ters fay nitelikli Van Fay Zonu (VFZ)’ndan kaynaklanmıştır. Depremde fay üzerine rastlayan mühendislik yapılarında 10 cm’ye ulaşan yerdeğiştirmenin izlendiği bir yüzey deformasyonu gelişmiştir. VFZ karada D-B genel doğrultusunda ve 28 km uzunluğundadır. Fayın batı ucu Van Gölü içerisindedir. Bu çalışmada, VFZ’nun kara ve deniz araştırma yöntemleri kullanılarak detay haritalanması, Van Gölü’ndeki sualtı devamlılığının incelenmesi, kara ve sualtı verilerinin ortak değerlendirilmesi ile Edremit Körfezi’nin Kuvaterner’deki tektonik yapısı ve evriminin ortaya konulması amaçlanmıştır. Kara verisi, VFZ tavan ve taban bloğunda Kuvaterner birimlerini etkileyen D-B uzanımlı kıvrım eksenlerinin varlığını göstermiştir. Kıyı ötesi çalışmalarda ise sığ sismik profilleme (GeoAcuoustics) ile çok ışınlı batimetrik veri toplanması çalışmaları sonucunda VFZ’nun sualtı bölümünün karaya benzer özellikler sergilediği ortaya konmuştur. Sismik kesitlerde göl tabanında yer alan Kuvaterner istifinde, eksenleri fay zonunun uzanımına paralel olan kıvrımlar fayın her iki bloğunda da açıkça görülmektedir. Çarpanak burnunun devamındaki su altı sırtı, karada olduğu gibi fayın tavan bloğundaki bir yükselim yapısına karşılık gelmektedir. 23 Ekim 2011 depremi ile ilişkili yüzey deformasyonları VFZ’nun tavan bloğundaki geniş bir zonda gelişmiştir. Araştırma bulguları, VFZ boyunca Kuvaterner’de meydana gelen deformasyonların en son depremde gelişen deformasyonlarla uyumlu olduğunu göstermiştir
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