Essential Oil Composition of Two Grammosciadium DC Species, G. platycarpum (Boiss et Hausskn) Schischk and G. macrodon Boiss (Apiaceae), from Turkey

Purpose: To investigate and compare the essential oil composition of two Grammosciadium species obtained by hydrodistillationMethods: The essential oil of the aerial parts of two species was obtained by hydrodistillation and analyzed by gas chromatography (GC) and gas chromatography - mass spectrometry (GC-MS).Results: In G. platycarpum, twenty-seven compounds were identified representing 99.3 % of the total oil. The major constituents of the oil were limonene (28.4 %), β-pinene (16.1 %), β-selinene (15.9 %), δ- 3-carene (11.2 %), α-farnesene (6.0 %) and p - cymene (4.7 %). The oil of G. macrodon contained thirty-seven components representing 94.4 % of the total oil, with caryophyllene oxide (15.9 %), germacrene - D (12.4 %), β-caryophyllene (11.5 %), δ-3 - carene (10.1 %) and cyclohexane (4.6 %) as the main constituents.Conclusion: The essential oil composition of G. macrodon was analysed for the first time, the most abundant constituents being caryophyllene oxide, and cyclohexane.Keywords: Grammosciadium macrodon, Grammosciadium platycarpum, Essential oil, Limonene, Caryophyllene oxide, Germacrene - D, β-Caryophyllene, δ-3-Caren

Durağan Durum Görsel Uyaran Potansiyellerinden Fourier Dönüşümü ile Üç Farklı Frekansın Kestirimi

Durağan durum görsel uyarılmış potansiyeller (DDGUP), diğer beyin bilgisayar ara yüzü (BBA) tekniklerine oranla oldukça yüksek sinyal-gürültü oranları ve bilgi aktarım hızına sahip oldukları için EEG çalışmalarında sıkça kullanılır. Ayrıca durağan durum paradigmaları, dinamik neokorteks süreçlerinde tercih edilen frekansları karakterize etmek için de kullanılır. Kısa eğitim süresine sahip olan DDGUP’lar, pratik uygulamalarda önemli bir rol oynar. Sinyalleri komuta dönüştürmekte kullanılan, sinyal işleme algoritmaları, BBA sistemlerinin performansını arttırmak için kilit öneme sahiptir. Buna ek olarak, DDGUP sinyallerinin birbirinden farklı yöntemlerle sınıflandırılmasını araştıran çok az çalışma vardır. Bu çalışmada, internetten açık erişim ile alınan veri seti (AVI SSVEP Dataset) üzerinde analizler yapılmıştır. Veri setindeki EEG kayıtları, katılımcılar, rengi siyahtan beyaza hızla değişen yedi farklı frekansta yanıp sönen bir kutuya baktıkları durumda kaydedilmiştir. Oksipital bölgeden kaydedilen DDGUP sinyalleri ilk olarak Hızlı Fourier Dönüşümü uygulanarak, sinyal alt bantlarına (delta, teta, alfa, beta ve gama) ayrılmıştır. Alt bantların her biri için enerji ve varyans öznitelik vektörleri çıkarılmıştır. Öznitelikler altı temel sınıflandırıcı (LDA, k-NN, SVM, Naive Bayes, Topluluk Öğrenmesi, Karar Ağacı) ile sınıflandırılmıştır. Sınıflandırma performansları birbirleri ile karşılaştırılmıştır. Sınıflandırma 5-kat çapraz doğrulama modeli ve hata matrisinden doğruluk değerleri çıkarılarak analiz edilmiştir. Katılımcılar ayrı ayrı göz önüne alındığında %100’e varan sınıflandırma başarımı SVM ve k-NN sınıflandırıcılarında elde edilirken, ortalamalara göre en yüksek başarım Topluluk Öğrenmesi sınıflandırıcısında %79,73 olarak elde edilmiştir

Effectiveness of Low-Level Laser Therapy in Chronic Plantar Fasciitis Conservative Treatment

Introduction:This study aimed to evaluate the effectiveness of low-level laser treatment (LLLT) for treating chronic plantar fasciitis (PF).Methods:The records of 60 patients with PF were retrospectively examined in this research. Thirty patients who have been applied LLLT and given exercise program constituted a treatment group. On the other side, 30 patients who have been given exercises but not applied LLLT was selected as a control group. Along with exercise, the treatment group underwent a 10-day continuous, 12-minute, 1.6 W, 808 nm wavelength diode laser treatment using galium-aluminum-arsenide. The American Orthopaedic Foot and Ankle Society (AOFAS) ankle-hindfoot scale and the Foot Function Index (FFI) were used to assess the patients’ foot discomfort and functional condition while they were at rest, taking their first steps, and during activities. These assessments were all documented before, after, and after two months of treatment.Results:In the treatment group, all VAS, FFI, and AOFAS scores except alignment score has been significantly improved both in the first and the second months compared to the initial state (p<0.05). The improvement in these scores was higher in the treatment group than in the control group in the first and the second months both (p<0.05).Conclusion:These findings confirm that LLLT is an effective and reliable therapy choice in the conservative management of PF

An ethno-veterinary study on plants used for the treatment of livestock diseases in Genç (Bingöl-Turkey)

81-88There are a very limited number of studies on plants traditionally used in animal diseases in Turkey. As a result, valuable information is getting lost. Traditional plant use in Genç District (Turkey) was recorded by semi-structured interviews with breeders and shepherds. The collected information was subjected to quantitative analysis using the informant consensus factor. It was recorded that a total of 53 plants from 24 families were used in the traditional treatment of animal diseases. 8 of these plants are endemic plants with a narrow distribution area and were recorded for the first time by us. The breeders stated that they applied such plants to animals with peace in mind as these plants had been used for human treatment as well. This study is the first ethnoveterinary study conducted in the province. Phytochemical studies need to be carried out on medicinal plants used in livestock around Bingöl Province. We believe that the use of this preliminary information obtained from ethnoveterinary studies by researchers will contribute to the production of natural animal medicines

Importance of Labarotory Parameters in Obstructive Sleep Apnea

Objective Obstructive sleep apnea (OSA) is associated with intermittent hypoxia. OSA leads to increased sympathetic activation, oxidative stress, vascular endothelial dysfunction, coagulation disorders and metabolic dysregulation. These disturbances increase the the risk of inflammation and cardiovascular diseases. The purpose of this article is to review the laboratory parameters of OSA patients without any comorbidities. Materials and Methods This retrospective study of consecutive 675 patients who had polysomnography, was conducted on one hundred and thirty patients who did not have any comorbidities. Laboratory values of patients were evaluated. Patients were grouped according to apnea-hypopnea index (AHI). Group 1 (n=17) AHI 30. Results There were 88 men (67.7%) and 42 women (32.3%) in the study. Mean age, body mass index, Epworth score and AHI were 41.6±11.3 (16-75), 29.6±6.3 (17.1-65.7) 9.9±5.5, 6.2±11.34, respectively. Serum glucose, cholesterol and triglyceride levels were higher in group 4 (p=0.03, p=0.04, p=0.02, respectively). Uric acid and fibrinogen levels were higher in patients with higher AHI (p=0.038). Conclusion Our study indicates that increased blood glucose, uric acid and dyslipidemia are associated with OSA regardless of comorbidities

Different features of lung involvement in Niemann-Pick disease and Gaucher disease

SummaryBackgroundNiemann-Pick disease (NPD) and Gaucher disease (GD) are well-known lysosomal storage diseases. Respiratory system involvement is an important cause of morbidity and mortality in patients with NPD and GD.ObjectivesWe tried to assess the clinical, radiological, and histological features of GD and NPD patients with lung involvement.MethodsWe reviewed medical history, physical examination, radiological, and histological data of 10 NPD and 7 GD patients.ResultsThe most common respiratory symptoms were recurrent lung infection and dyspnea. Although lung examination results in 6 NPD patients were normal, they had lung involvement; 3 patients were diagnosed as NPD directly via lung biopsy during investigation of recurrent lung infection or interstitial lung disease. All GD patients but 1 had respiratory system symptoms at the time of diagnosis. Hepatopulmonary syndrome was present in 4 GD patients. A ground-glass pattern and atelectasis were 2 important high-resolution computed tomography features in the NPD and GD patients. Flexible bronchoscopy and bronchoalveolar lavage were used for emergency extraction of bronchial casts in 1 NPD patient.ConclusionsLung involvement in NPD and GD patients should be included in the differential diagnosis of interstitial lung disease. Besides interstitial appearance on HRCT, atelectasis related to bronchial cast and bronchiectasis are other radiological findings in these group of patients. Analysis of bronchoalveolar fluid and lung biopsy provide very important clues for diagnosis. Hepatopulmonary syndrome is an important vascular complication observed in GD patients

An ethno-veterinary study on plants used for the treatment of livestock diseases in Genç (Bingöl-Turkey)

There are a very limited number of studies on plants traditionally used in animal diseases in Turkey. As a result, valuable information is getting lost. Traditional plant use in Genç District (Turkey) was recorded by semi-structured interviews with breeders and shepherds. The collected information was subjected to quantitative analysis using the informant consensus factor. It was recorded that a total of 53 plants from 24 families were used in the traditional treatment of animal diseases. 8 of these plants are endemic plants with a narrow distribution area and were recorded for the first time by us. The breeders stated that they applied such plants to animals with peace in mind as these plants had been used for human treatment as well. This study is the first ethno-veterinary study conducted in the province. Phytochemical studies need to be carried out on medicinal plants used in livestock around Bingöl Province. We believe that the use of this preliminary information obtained from ethnoveterinary studies by researchers will contribute to the production of natural animal medicines

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