19 research outputs found
Studying Pub M ed usages in the field for complex problem solving: Implications for tool design
Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/97504/1/asi22796.pd
Demonstration of fully integrated parity-time-symmetric electronics
Harnessing parity-time (PT) symmetry with balanced gain and loss profiles has
created a variety of opportunities in electronics from wireless energy transfer
to telemetry sensing and topological defect engineering. However, existing
implementations often employ ad-hoc approaches at low operating frequencies and
are unable to accommodate large-scale integration. Here, we report a fully
integrated realization of PT-symmetry in a standard complementary
metal-oxide-semiconductor technology. Our work demonstrates salient PT-symmetry
features such as phase transition as well as the ability to manipulate
broadband microwave generation and propagation beyond the limitations
encountered by exiting schemes. The system shows 2.1 times bandwidth and 30
percentage noise reduction compared to conventional microwave generation in
oscillatory mode and displays large non-reciprocal microwave transport from
2.75 to 3.10 gigahertz in non-oscillatory mode due to enhanced nonlinearities.
This approach could enrich integrated circuit (IC) design methodology beyond
well-established performance limits and enable the use of scalable IC
technology to study topological effects in high-dimensional non-Hermitian
systems.Comment: 52 pages (16 pages Main Text, 28 pages Supplementary Materials, 4
pages reference), 27 figures (4 figures Main Text, 23 figures Supplementary
Materials), 93 references (50 references Main Text, 43 references
Supplementary Materials
Open Biomedical Ontology-based Medline exploration
Abstract
Background
Effective Medline database exploration is critical for the understanding of high throughput experimental results and the development of novel hypotheses about the mechanisms underlying the targeted biological processes. While existing solutions enhance Medline exploration through different approaches such as document clustering, network presentations of underlying conceptual relationships and the mapping of search results to MeSH and Gene Ontology trees, we believe the use of multiple ontologies from the Open Biomedical Ontology can greatly help researchers to explore literature from different perspectives as well as to quickly locate the most relevant Medline records for further investigation.
Results
We developed an ontology-based interactive Medline exploration solution called PubOnto to enable the interactive exploration and filtering of search results through the use of multiple ontologies from the OBO foundry. The PubOnto program is a rich internet application based on the FLEX platform. It contains a number of interactive tools, visualization capabilities, an open service architecture, and a customizable user interface. It is freely accessible at:
http://brainarray.mbni.med.umich.edu/brainarray/prototype/pubonto
.http://deepblue.lib.umich.edu/bitstream/2027.42/112693/1/12859_2009_Article_3295.pd
Fully integrated topological electronics
Topological insulators (TIs) have attracted significant attention in photonics and acoustics due to their unique physical properties and promising applications. Electronics has recently emerged as an exciting arena to study various topological phenomena because of its advantages in building complex topological structures. Here, we explore TIs on an integrated circuit (IC) platform with a standard complementary metal-oxide-semiconductor technology. Based on the Su-Schrieffer-Heeger model, we design a fully integrated topological circuit chain using multiple capacitively-coupled inductor-capacitor resonators. We perform comprehensive post-layout simulations on its physical layout to observe and evaluate the salient topological features. Our results demonstrate the existence of the topological edge state and the remarkable robustness of the edge state against various defects. Our work shows the feasibility and promise of studying TIs with IC technology, paving the way for future explorations of large-scale topological electronics on the scalable IC platform.ISSN:2045-232
Fully integrated parity–time-symmetric electronics
Harnessing parity–time symmetry with balanced gain and loss profiles has created a variety of opportunities in electronics from wireless energy transfer to telemetry sensing and topological defect engineering. However, existing implementations often employ ad hoc approaches at low operating frequencies and are unable to accommodate large-scale integration. Here we report a fully integrated realization of parity–time symmetry in a standard complementary metal–oxide–semiconductor process technology. Our work demonstrates salient parity–time symmetry features such as phase transition as well as the ability to manipulate broadband microwave generation and propagation beyond the limitations encountered by existing schemes. The system shows 2.1 times the bandwidth and 30% noise reduction compared to conventional microwave generation in the oscillatory mode, and displays large non-reciprocal microwave transport from 2.75 to 3.10 GHz in the non-oscillatory mode due to enhanced nonlinearities. This approach could enrich integrated circuit design methodology beyond well-established performance limits and enable the use of scalable integrated circuit technology to study topological effects in high-dimensional non-Hermitian systems.ISSN:1748-3387ISSN:1748-339
The validation of a Mandarin version of the Empathy Components Questionnaire (ECQ-Chinese) in Chinese samples.
Empathy involves both empathic ability and empathic motivation. An important topic has been how to measure empathic ability and motivation simultaneously in both clinical and non-clinical samples and across different cultures. The Empathy Components Questionnaire (ECQ) is a self-report questionnaire that measures empathic ability and motivation in a questionnaire. The current study aimed to validate the Mandarin Chinese version of the ECQ (ECQ-Chinese) in three Chinese samples. In study 1, a total of 538 Chinese participants (Sample 1) completed the ECQ-Chinese via an online survey, and existing measures of empathy and related constructs which were used for criterion validity. In study 2, a total of 104 participants (Sample 2) were recruited again from sample 1 and completed the ECQ-Chinese three weeks later to investigate test-retest reliability. In study 3, a further 324 participants (Sample 3) completed the ECQ-Chinese for confirmatory factor analysis. The results showed that the ECQ-Chinese has a good internal consistency reliability, split-half reliability, and criterion validity (Study 1), and a good test-retest reliability (Study 2). Further, Study 3 found that a 22-item ECQ-Chinese consisting of five subscales had a good construct validity, convergence validity and discriminate validity, demonstrating it to be a suitable tool for the measurement of empathic ability and motivation in Chinese samples and to carry out cross-cultural studies of empathy and its components