Performing arts review : the journal of management and law of the arts

<p>‘n’ is the number of pairs of <i>in vivo</i> and <i>ex vivo</i> ROIs identified in each category.</p><p>The average <i>in vivo</i> and <i>ex vivo</i> T₂ values (mean ± standard deviation) for lymph nodes, <i>in situ</i> cancers, and invasive cancers.</p

Plots of <i>in vivo</i> versus <i>ex vivo</i> average T₂ values over ROIs from 11 mice.

<p>(a) lymph nodes, (b) <i>in situ</i> cancers, and (c) invasive cancers. The gray line is the linear fit through the points. The linear relationship between <i>in vivo</i> and <i>ex vivo</i> T₂s, the correlation coefficient (r) and p value are given on the plot.</p

Number of ROIs for lymph nodes, <i>in situ</i> cancers, and invasive cancers found in each mouse (named A to O) that matched between <i>in vivo</i> and <i>ex vivo</i> MRI experiments.

<p>Note that four mice (A, B, F and G) died before T₂ measurements could be completed.</p><p>Number of ROIs for lymph nodes, <i>in situ</i> cancers, and invasive cancers found in each mouse (named A to O) that matched between <i>in vivo</i> and <i>ex vivo</i> MRI experiments.</p

(a) H&E stained slice through an invasive cancer, (b) <i>ex vivo</i> T2W image, (c) corresponding ADC map (×10⁻³ mm²/s), and (d) T₂ map (ms).

<p>The displayed image FOV is 15.0 × 15.0 mm.</p

T2W <i>in vivo</i> image (left panel) matched with the corresponding <i>ex vivo</i> image (right panel) showing a mouse mammary gland from head to tail (top to bottom)–near the neck, heart, liver, below the kidney, and near the legs, respectively.

<p>Matching features (all invasive cancers) in the <i>in vivo</i> and <i>ex vivo</i> images, identified by visual inspection, were circled with the same color. The displayed image FOV is 25.6 × 25.6 mm.</p

Photograph of excised skin from a mouse after treatment with formaldehyde before preparation for <i>ex vivo</i> imaging.

<p>The scale of the ruler is in millimeters.</p

Matched invasive cancers (circled by the same color) from <i>in vivo</i> images (left panel) and <i>ex vivo</i> images (right panel) of a mouse mammary gland.

<p>(a, b) T2W images; (c, d) ADC maps (×10⁻³ mm²/s); (e, f) T₂ maps (ms). The displayed image FOV is 25.6 × 25.6 mm.</p

The detailed list of ingredients in low fat, high animal fat, and high fructose diets.

<p>The detailed list of ingredients in low fat, high animal fat, and high fructose diets.</p

Example of T2W images (top row), water peak height (PH) images (maps) (middle row), and fat peak height (PH) images (maps) (bottom row) for LFD (left panel), HAFD (middle panel), and HFruD (right panel) fed SV40 mice.

<p>The color bar indicates the normalized signal intensity values, which were obtained by dividing the average of water peak height intensity over the muscle ROI.</p

Plots of spectrum (black dots) measured from the LFD (top), HAFD (middle), and HFruD (bottom) fed SV40 mice, and corresponding fitted the spectrum (color lines) with a combination of Gaussian and Lorentz functions.

<p>1: Olefin (−C<b>H</b> = C<b>H</b>−) at 5.4 ppm, 2: Water (<b>H</b>₂O) at 4.65 ppm, 3: Diallyl (= CH−C<b>H</b>₂−CH =) at 2.8 ppm, 4: α-Methylene to carboxyl at 2.3 ppm, 5: Allyl (−C<b>H</b>₂−CH = CH−) at 2.1 ppm, 6: Methylene (−C<b>H</b>₂−) at 1.3 ppm, 7: Methyl (−C<b>H</b>₃) at 0.9 ppm. The locations of 1 mm³ ROIs (white squares) used for the PRESS pulse sequence are shown in the insets T2W images. The right panel shows examples of histological images from inguinal mammary glands.</p