Interpretation of 750 GeV Diphoton Excess at LHC in Singlet Extension of Color-octet Neutrino Mass Model

We propose that the possible 750 GeV diphoton excess can be explained in the color-octet neutrino mass model extended with a scalar singlet $\Phi$. The model generally contains $N_s$ species of color-octet, electroweak doublet scalars $S$ and $N_f$ species of color-octet, electroweak triplet $\chi$ or singlet $\rho$ fermions. While both scalars and fermions contribute to the production of $\Phi$ through gluon fusion, only the charged members induce the diphoton decay of $\Phi$. The diphoton rate can be significantly enhanced due to interference between the scalar and fermion loops. We show that the diphoton cross section can be from 3 to 10 fb for O(TeV) color-octet particles while evading all current LHC limits.Comment: 12 pages, 4 figures; v2: 13 pages, 4 figures, version to appear in EPJC, clarified a few things, updated numerical analysis using the most recent bound on color-octet fermions but without changing conclusions, corrected a mistake when quoting the branching ratio to Z gamma, added some references missed in v

Effect of state-dependent time delay on dynamics of trimming of thin walled structures

Acknowledgments This work was supported by the National Key R&D Program of China (2020YFA0714900), National Natural Science Foundation of China (52075205, 92160207, 52090054, 52188102).Peer reviewedPostprin

Optimization of Inner Dumping Uncovered Height with Partially Covered End Wall in Adjacent Surface Coal Mining Districts

In order to analyze the relationships of inner dumping with covered end wall in adjacent surface coal mining districts, a trough-shaped uncovered end wall model was put forward. A mathematical model concerning uncovered end wall height (UEWH) was established based on minimum cost method. The inner dump capacity was considered regarding its effect on UEWH. Besides, a comprehensive model was established for calculating optimal UEWH in inner dumping with partially covered end wall mode and a shifting distance optimization model based on cost compensation method for building a provisional haulage system to connect inner dump. As for case study in Huolinhe number 1 surface coal mine, research results show that optimal UEWH was 225 m between North Pit and South Pit whereas in number 3 mining district of North Open-Pit Mine it was 23.50 m when making its transition from cross mining to mining along strike. Nevertheless, due to limited inner dump capacity, inner dump height in South and North mining districts shall be appropriately increased and closed pits from earlier period shall be fully utilized to make room for inner dumping with partially uncovered end walls

Learning Transformation-Invariant Local Descriptors With Low-Coupling Binary Codes

Despite the great success achieved by prevailing binary local descriptors, they are still suffering from two problems: 1) vulnerable to the geometric transformations; 2) lack of an effective treatment to the highly-correlated bits that are generated by directly applying the scheme of image hashing. To tackle both limitations, we propose an unsupervised Transformation-invariant Binary Local Descriptor learning method (TBLD). Specifically, the transformation invariance of binary local descriptors is ensured by projecting the original patches and their transformed counterparts into an identical high-dimensional feature space and an identical low-dimensional descriptor space simultaneously. Meanwhile, it enforces the dissimilar image patches to have distinctive binary local descriptors. Moreover, to reduce high correlations between bits, we propose a bottom-up learning strategy, termed Adversarial Constraint Module , where low-coupling binary codes are introduced externally to guide the learning of binary local descriptors. With the aid of the Wasserstein loss, the framework is optimized to encourage the distribution of the generated binary local descriptors to mimic that of the introduced low-coupling binary codes, eventually making the former more low-coupling. Experimental results on three benchmark datasets well demonstrate the superiority of the proposed method over the state-of-the-art methods

Development of an in situ polymeric hydrogel implant of methylprednisolone for spinal injuries

Purpose: To prepare and characterize in situ gel-forming implants of methylprednisolone for the treatment of spinal cord injuries.Methods: In situ hydrogels of methylprednisolone were prepared by dispersing polylactide glycolic acid (PLGA) polymer and methylprednisolone in N-methyl-pyrrolidone solvent, and subsequent membrane sterilization. Hydrogels were prepared using varying concentrations of PLGA polymer. The physicochemical properties of hydrogels, including visual appearance, clarity, pH, viscosity, drug content, and in vitro drug release, were characterized. In vivo studies were performed to examine antiinflammatory activity (paw edema test) and in vivo motor function activity in a rat spinal injury model after injecting the hydrogels into rats.Results: The physicochemical properties of the gels were satisfactory. F1, F2, F3, and F4 formulations showed 99.67, 95.29, 88.89 and 88.20 % drug release, respectively, at the end of 7 days. In vivo antiinflammatory activity was highest for F1 (62.85 %). Motor function activity scores (arbitrary scale) for the F1, F2, F3 and F4 formulations were 4.82 ± 0.12, 4.70 ± 0.12, 4.68 ± 0.02, and 4.60 ± 0.05, respectively, and were higher (p < 0.05) for F1, F2 and F3) than for the standard (methylprednisolone, 30 mg/kg body weight, iv; activity score, 4.59 ± 0.20).Conclusions: The in situ hydrogels of methylprednisolone developed may be useful for the effective management of spinal cord injuries in patients. However, further investigations are required to ascertain their suitability for clinical use.Keywords: Methylprednisolone, In situ hydrogel, Spinal injury, Motor activity, Implan

Serum TRPA1 mediates the association between olfactory function and cognitive function

BackgroundOlfactory dysfunction was associated with poorer cognition. However, the association between transient receptor potential cation channel subfamily A member 1 (TRPA1) and cognitive function have not been studied. This study aimed to evaluate the mediation effect of TRPA1 on the association between olfactory and cognitive function among Chinese older adults.MethodsWe recruited 121 participants with cognitive impairment (CI) and 135 participants with normal cognition (NC) from a memory clinic and the “Shanghai Aging Study.” Olfactory identification of each participant was measured by the Sniffin’ Sticks Screening Test 12 (SSST-12). Serum TRPA1 were quantified using the Enzyme-Linked Immunosorbent Assay. The mediation effects of TRPA1 on the association between olfactory function and cognitive function were explored using mediation analysis.ResultsThe CI group had a significantly higher proportion of the high level of serum TRPA1 (58.7%) than the NC group (42.2%) (p = 0.0086). After adjusted for gender, age, and years of education, mediation analysis verified that TRPA1 partially mediated the association between SSST-12 and Mini Mental State Examination (MMSE). It also verified that TRPA1 partially mediated the association between the identification of peppermint and MMSE.ConclusionOur study emphasizes the mediation role of TRPA1 in the relationship between olfactory and cognitive function among older adults. Further research is necessary to explore the mechanism of TRPA1 on the relationship between olfactory and cognitive decline

The emergence, coalescence and topological properties of multiple exceptional points and their experimental realization

Non-Hermitian systems distinguish themselves from Hermitian systems by exhibiting a phase transition point called an exceptional point (EP), which is the point at which two eigenstates coalesce under a system parameter variation. Many interesting EP phenomena such as level crossings/repulsions in nuclear/molecular and condensed matter physics, and unusual phenomena in optics such as loss-induced lasing and unidirectional transmission can be understood by considering a simple 2x2 non-Hermitian matrix. At a higher dimension, more complex EP physics not found in two-state systems arises. We consider the emergence and interaction of multiple EPs in a four-state system theoretically and realize the system experimentally using four coupled acoustic cavities with asymmetric losses. We find that multiple EPs can emerge and as the system parameters vary, these EPs can collide and merge, leading to higher order singularities and topological characteristics much richer than those seen in two-state systems

Residual Stress-Driven Non-Euclidean Morphing in Origami Structures

Non-Euclidean surfaces are ubiquitous in numerous engineering fields, such as automotive, aerospace, and biomedical engineering domains. Morphing origami has numerous potential engineering applications, including soft robots, mechanical metamaterials, antennas, aerospace structures, and biomedical devices, owing to its intrinsic morphing features from two-dimensional (2D) planes to three-dimensional (3D) surfaces. However, the current one-dimensional (1D) hinge deformation-driven transformation of foldable origami with rigid or slightly deformable panels cannot achieve a 3D complex and large curvilinear morphing. Moreover, most active origami structures use thin hinges with soft materials on their creases, thus resulting in a lower load capability. This study proposes a novel origami morphing method that demonstrates large free-form surface morphing, e.g., Euclidean to non-Euclidean surface morphing with shape-locking. We embedded tensorial anisotropic stress in origami panels during the extrusion-based 3D printing of shape memory polymers. The extrusion-based 3D printing of isotropic shape memory polymers can produce tensorial anisotropic stress in origami panels during fabrication, which can realize large non-Euclidean surface morphing with multiple deformation modes. The connecting topology of the origami unit cells influences the global morphing behavior owing to the interaction of the deformation of adjacent panels. Non-Euclidean morphing integrated with four-dimensional (4D) printing can provide multimodal shape locking at material and structural levels. The non-Euclidean surface morphing caused by tensorial residual stress in the panel during 3D printing expands the design space of origami and kirigami structures