Constraining the ellipticity and frequency of binary neutron star remnant via its gravitational-wave and electromagnetic radiations

The nature of the merger remnant of binary neutron star (BNS) remains an open question. From the theoretical point of view, one possible outcome is a supra-massive neutron star (SMNS), which is supported by rigid rotation and through its survival of hundreds of seconds before collapsing into a black hole (BH). If this is the case, the SMNS can emit continuous gravitational waves (GW) and electromagnetic (EM) radiation, particularly in the X-ray band. In this work, the ellipticity and initial frequency of SMNS are constrained with a Bayesian framework using simulated X-ray and GW signals, which could be detected by The Transient High Energy Sky and Early Universe Surveyor (THESEUS) and Einstein Telescope (ET), respectively. We found that only considering the X-ray emission can not completely constrain the initial frequency and ellipticity of the SMNS, but it can reduce the ranges of the parameters. Afterwards, we can use the posterior distribution of the X-ray parameter estimates as a prior for the GW parameter estimates. It was found that the 95$\%$ credible region of the joint X-ray-GW analysis was about $10^5$ times smaller than that of the X-ray analysis alone.Comment: Accepted by MNRA

U-rank: Utility-oriented Learning to Rank with Implicit Feedback

Learning to rank with implicit feedback is one of the most important tasks in many real-world information systems where the objective is some specific utility, e.g., clicks and revenue. However, we point out that existing methods based on probabilistic ranking principle do not necessarily achieve the highest utility. To this end, we propose a novel ranking framework called U-rank that directly optimizes the expected utility of the ranking list. With a position-aware deep click-through rate prediction model, we address the attention bias considering both query-level and item-level features. Due to the item-specific attention bias modeling, the optimization for expected utility corresponds to a maximum weight matching on the item-position bipartite graph. We base the optimization of this objective in an efficient Lambdaloss framework, which is supported by both theoretical and empirical analysis. We conduct extensive experiments for both web search and recommender systems over three benchmark datasets and two proprietary datasets, where the performance gain of U-rank over state-of-the-arts is demonstrated. Moreover, our proposed U-rank has been deployed on a large-scale commercial recommender and a large improvement over the production baseline has been observed in an online A/B testing

Linking nutrient strategies with plant size along a grazing gradient: Evidence from Leymus chinensis in a natural pasture

AbstractStudying the changes in nutrient use strategies induced by grazing can provide insight into the process of grassland degradation and is important for improving grassland quality and enhancing ecosystem function. Dominant species in meadow steppe can optimize their use of limiting resources; however, the regulation of nutrient use strategies across grazing gradients is not fully understood. Therefore, in this study, we report an in situ study in which the impact of grazing rates on nutrient use strategies of Leymus chinensis, the dominant plant species in eastern Eurasian temperate steppes, was investigated. We conducted a large randomized controlled experiment (conducted continuously for five years in grassland plots in a natural pasture in Hailar, eastern Mongolia Plateau, China) to assess the effects of grazing rate treatments (0.00, 0.23, 0.34, 0.46, 0.69, and 0.92 adult cattle unit (AU) ha−1) on L. chinensis along a grazing gradient and employed a random sampling approach to compare the accumulation, allocation, and stoichiometry of C, N, and P in leaves and stems. Our findings demonstrated the follows: (i) The height of L. chinensis decreased with an increase in the grazing gradient, and the concentrations of C, N, and P significantly increased; (ii) the accumulation of C, N, and P per individual was negatively correlated with the concentration of aboveground tissues, suggesting that there was a tradeoff in L. chinensis between nutrient accumulation and concentration at the individual scale; (iii) the leaf-to-stem ratio of C, N, and P accumulation increased with grazing intensity, indicating a tradeoff in nutrient allocation and plant size at the individual plant level; and (iv) grazing rates were negatively correlated with the ratios of C:N and C:P in the stem; however, these ratios in leaves significantly increased with grazing intensity. Our findings suggest that L. chinensis in meadow steppe adapts to grazing disturbance through tradeoffs between plant size and nutrient use strategies. Moreover, our results imply that grazing produces a compensatory effect on nutrient use efficiency between the stems and leaves of L. chinensis

Surface-Based Regional Homogeneity in First-Episode, Drug-Naive Major Depression: A Resting-State fMRI Study

Background. Previous volume-based regional homogeneity (ReHo) studies neglected the intersubject variability in cortical folding patterns. Recently, surface-based ReHo was developed to reduce the intersubject variability and to increase statistical power. The present study used this novel surface-based ReHo approach to explore the brain functional activity differences between first-episode, drug-naive MDD patients and healthy controls. Methods. Thirty-three first-episode, drug-naive MDD patients and 32 healthy controls participated in structural and resting-state fMRI scans. MDD patients were rated with a 17-item Hamilton Rating Scale for Depression prior to the scan. Results. In comparison with the healthy controls, MDD patients showed reduced surface-based ReHo in the left insula. There was no increase in surface-based ReHo in MDD patients. The surface-based ReHo value in the left insula was not significantly correlated with the clinical information or the depressive scores in the MDD group. Conclusions. The decreased surface-based ReHo in the left insula in MDD may lead to the abnormal top-down cortical-limbic regulation of emotional and cognitive information. The surface-based ReHo may be a useful index to explore the pathophysiological mechanism of MDD.</p

Transiently Impaired Endothelial Function During Thyroid Hormone Withdrawal in Differentiated Thyroid Cancer Patients

PURPOSE: Endothelial dysfunction, which was associated with chronic hypothyroidism, was an early event in atherosclerosis. Whether short-term hypothyroidism following thyroxine withdrawal during radioiodine (RAI) therapy was associated with endothelial dysfunction in patients with differentiated thyroid cancer (DTC) was unclear. Aim of the study was to assess whether short-term hypothyroidism could impair endothelial function and the accompanied metabolic changes in the whole process of RAI therapy. METHODS: We recruited fifty-one patients who underwent total thyroidectomy surgery and would accept RAI therapy for DTC. We analyzed thyroid function, endothelial function and serum lipids levels of the patients at three time points: the day before thyroxine withdrawal(P RESULTS: We analyzed the changes of FMD, thyroid function and lipids at three time points. FMD(P CONCLUSION: Endothelial function was transiently impaired in DTC patients at short-term hypothyroidism state during the RAI therapy, and immediately returned to the initial state after restoring TSH suppression therapy

Dendritic cell subsets dynamics and cytokine production in SIVmac239-infected Chinese rhesus macaques

BACKGROUND: Several studies have demonstrated that SIV infection progresses more slowly to experimental AIDS in Chinese rhesus macaques (Ch Rhs) than in Indian rhesus macaques (Ind Rhs). Here we investigated the dynamic and functional changes in dendritic cell (DC) subsets in SIVmac239-infected Ch Rhs. RESULTS: The numbers of both mDC and pDC strongly fluctuated but were not significantly changed during the acute and chronic phases of infection. However, the concentration of both poly (I:C)-induced IL-12 and HSV-1-induced IFN-α significantly increased in the acute phase of infection but returned to normal levels at the chronic phase of infection. The peak of IFN-α emerged earlier than that of IL-12, and it had a significantly positive correlation with IL-12, which indicated that IFN-α may initiate the immune activation. We also found that only the concentration of IFN-α was positively correlated with CD4+ T-cell counts, but it was negatively correlated with viral load. CONCLUSION: High levels of IFN-α in the early stage of infection may contribute to effective control of virus replication, and normal levels of IFN-α during chronic infection may help Ch Rhs resist the disease progression. The change in DC subsets dynamics and cytokine production may help further our understanding of why Ch Rhs are able to live longer without progressing to an AIDS-like illness

Surface-Based Regional Homogeneity in First-Episode, Drug-Na\ve Major Depression: A Resting-State fMRI Study

Background. Previous volume-based regional homogeneity (ReHo) studies neglected the intersubject variability in cortical folding patterns. Recently, surface-based ReHo was developed to reduce the intersubject variability and to increase statistical power. The present study used this novel surface-based ReHo approach to explore the brain functional activity differences between firstepisode, drug-naïve MDD patients and healthy controls. Methods. Thirty-three first-episode, drug-naïve MDD patients and 32 healthy controls participated in structural and resting-state fMRI scans. MDD patients were rated with a 17-item Hamilton Rating Scale for Depression prior to the scan. Results. In comparison with the healthy controls, MDD patients showed reduced surfacebased ReHo in the left insula. There was no increase in surface-based ReHo in MDD patients. The surface-based ReHo value in the left insula was not significantly correlated with the clinical information or the depressive scores in the MDD group. Conclusions. The decreased surface-based ReHo in the left insula in MDD may lead to the abnormal top-down cortical-limbic regulation of emotional and cognitive information. The surface-based ReHo may be a useful index to explore the pathophysiological mechanism of MDD

Design, synthesis, structural, and spectra characterize of Metal (II) Formate complexes [M(O2CH)2]•n(Solvent) (M =Mn, Cu)

oai:ojs.pkp.sfu.ca:article/1457Formate anion is the simplest carboxylate, compared with other carboxylate, it owns more excellent coordination ability. We used M(OAc)2·n H2O (M=Mn, Cu) as a raw starting material, hydrothermal synthesis methods assisted byDMF hydrolysis which produced the formyl were adopted to prepare metal(II) formates complexes, Mn(HCOO)3·NH2(CH3)2 (1) and Cu(HCOO)3·H3C2O3 (2). The as-prepared products were characterized by elemental analysis, IR spectroscopy, X-ray single-crystal, powder diffraction and thermogravimetric analysis. Structural analysis shows that complex 1 is three-dimensional grid shapes, and complex 2 is a 1D chain structure

Identification of avian polyomavirus and its pathogenicity to SPF chickens

The research aimed to study an Avian polyomavirus strain that was isolated in Shandong, China. To study the pathogenicity of APV in SPF chickens, and provide references for epidemiological research and disease prevention and control of APV. The genetic characterization of APV strain (termed APV-20) was analyzed and the pathogenicity of APV was investigated from two aspects: different age SPF chickens, and different infection doses. The results revealed that the APV-20 exhibits a nucleotide homology of 99% with the other three APV strains, and the evolution of APV In China was slow. In addition, the APV-20 infection in chickens caused depression, drowsiness, clustering, and fluffy feathers, but no deaths occurred in the infected chickens. The main manifestations of necropsy, and Hematoxylin and Eosin staining (HE) showed that one-day-old SPF chickens were the most susceptible, and there was a positive correlation between viral load and infection dose in the same tissue. This study showed that SPF chickens were susceptible to APV, and an experimental animal model was established. This study can provide a reference for the pathogenic mechanism of immune prevention and control of APV