Ultracold Dipolar Gas of Fermionic 23^{23}Na40^{40}K Molecules in their Absolute Ground State

We report on the creation of an ultracold dipolar gas of fermionic $^{23}$Na$^{40}$K molecules in their absolute rovibrational and hyperfine ground state. Starting from weakly bound Feshbach molecules, we demonstrate hyperfine resolved two-photon transfer into the singlet ${\rm X}^1\Sigma^+ |v{=}0,J{=}0\rangle$ ground state, coherently bridging a binding energy difference of 0.65 eV via stimulated rapid adiabatic passage. The spin-polarized, nearly quantum degenerate molecular gas displays a lifetime longer than 2.5 s, highlighting NaK's stability against two-body chemical reactions. A homogeneous electric field is applied to induce a dipole moment of up to 0.8 Debye. With these advances, the exploration of many-body physics with strongly dipolar Fermi gases of $^{23}$Na$^{40}$K molecules is in experimental reach.Comment: 5 pages, 5 figure

Two-Photon Pathway to Ultracold Ground State Molecules of 23^{23}Na40^{40}K

We report on high-resolution spectroscopy of ultracold fermionic \nak~Feshbach molecules, and identify a two-photon pathway to the rovibrational singlet ground state via a resonantly mixed \Bcres intermediate state. Photoassociation in a $^{23}$Na-$^{40}$K atomic mixture and one-photon spectroscopy on \nak~Feshbach molecules reveal about 20 vibrational levels of the electronically excited \ctrip state. Two of these levels are found to be strongly perturbed by nearby \Bsing states via spin-orbit coupling, resulting in additional lines of dominant singlet character in the perturbed complex {${\rm B}^1\Pi |v{=}4\rangle {\sim} {\rm c}^3\Sigma^+ | v{=}25\rangle$}, or of resonantly mixed character in {${\rm B}^1\Pi | v{=}12 \rangle {\sim}{\rm c}^3\Sigma^+ | v{=}35 \rangle$}. The dominantly singlet level is used to locate the absolute rovibrational singlet ground state ${\rm X}^1\Sigma^+ | v{=}0, J{=}0 \rangle$ via Autler-Townes spectroscopy. We demonstrate coherent two-photon coupling via dark state spectroscopy between the predominantly triplet Feshbach molecular state and the singlet ground state. Its binding energy is measured to be 5212.0447(1) \cm, a thousand-fold improvement in accuracy compared to previous determinations. In their absolute singlet ground state, \nak~molecules are chemically stable under binary collisions and possess a large electric dipole moment of $2.72$ Debye. Our work thus paves the way towards the creation of strongly dipolar Fermi gases of NaK molecules.Comment: 23 pages, 8 figure

Regulation of Leukocyte-Derived Matrix Metalloproteinases and Azurophilic Enzymes in Human Diabetic Ketoacidosis

Diabetic Ketoacidosis (DKA) is associated with pediatric cerebrovascular-related complications. DKA-associated inflammation instigates leukocyte adherence to the brain microvascular endothelium. As adhered leukocytes release enzymes that compromise vascular integrity, we questioned a role for leukocyte-derived matrix metalloproteinases (MMPs) and azurophilic enzymes (elastase, proteinase-3, myeloperoxidase). Our aims were to measure leukocyte-derived enzymes in DKA plasma, determine associations with DKA severity and investigate their effect on the cerebrovascular endothelium. Plasma was obtained from children with type-1 diabetes, either in acute DKA or insulin-controlled. DKA was associated with altered plasma levels of ↓MMP-2, ↑MMP-8, ↑MMP-9 and ↑TIMP-4, which are largely leukocyte in origin. DKA was also associated with elevated plasma leukocyte elastase, proteinase-3 and myeloperoxidase. MMP-8, MMP-9 and proteinase-3 were positively correlated with DKA severity. Azurophilic enzymes decreased ZO-1 and degraded β-catenin in cerebrovascular endothelium. In summary, DKA is associated with dynamic regulation of leukocyte proteolytic enzymes that can impair blood brain barrier integrity

Coherent Microwave Control of Ultracold 23^{23}Na40^{40}K Molecules

We demonstrate coherent microwave control of rotational and hyperfine states of trapped, ultracold, and chemically stable $^{23}$Na$^{40}$K molecules. Starting with all molecules in the absolute rovibrational and hyperfine ground state, we study rotational transitions in combined magnetic and electric fields and explain the rich hyperfine structure. Following the transfer of the entire molecular ensemble into a single hyperfine level of the first rotationally excited state, $J{=}1$, we observe collisional lifetimes of more than $3\, \rm s$, comparable to those in the rovibrational ground state, $J{=}0$. Long-lived ensembles and full quantum state control are prerequisites for the use of ultracold molecules in quantum simulation, precision measurements and quantum information processing.Comment: 5 pages, 4 figure

Ultracold Fermionic Feshbach Molecules of 23^{23}Na40^{40}K

We report on the formation of ultracold fermionic Feshbach molecules of $^{23}$Na$^{40}$K, the first fermionic molecule that is chemically stable in its ground state. The lifetime of the nearly degenerate molecular gas exceeds 100 ms in the vicinity of the Feshbach resonance. The measured dependence of the molecular binding energy on the magnetic field demonstrates the open-channel character of the molecules over a wide field range and implies significant singlet admixture. This will enable efficient transfer into the singlet vibrational ground state, resulting in a stable molecular Fermi gas with strong dipolar interactions.Comment: 5 pages, 4 figure

Correlated photon-pair generation in reverse-proton-exchange PPLN waveguides with integrated mode demultiplexer at 10 GHz clock

We report 10-ps correlated photon pair generation in periodically-poled reverse-proton-exchange lithium niobate waveguides with integrated mode demultiplexer at a wavelength of 1.5-um and a clock of 10 GHz. Using superconducting single photon detectors, we observed a coincidence to accidental count ratio (CAR) as high as 4000. The developed photon-pair source may find broad application in quantum information systems as well as quantum entanglement experiments.Comment: 6 pages, 4 figures, presented at 2007 CLEO conferenc

Single-photon detection timing jitter in a visible light photon counter

Visible light photon counters (VLPCs) offer many attractive features as photon detectors, such as high quantum efficiency and photon number resolution. We report measurements of the single-photon timing jitter in a VLPC, a critical performance factor in a time-correlated single-photon counting measurement, in a fiber-coupled closed-cycle cryocooler. The measured timing jitter is 240 ps full-width-at-half-maximum at a wavelength of 550 nm, with a dark count rate of 25 000 counts per second. The timing jitter increases modestly at longer wavelengths to 300 ps at 1000 nm, and increases substantially at lower bias voltages as the quantum efficiency is reduced

The extended narrow-line region of two type-I quasi-stellar objects

We investigate the narrow-line region (NLR) of two radio-quiet QSOs, PG1012+008 and PG1307+085, using high signal-to-noise spatially resolved long-slit spectra obtained with FORS1 at the Very Large Telescope. Although the emission is dominated by the point-spread function of the nuclear source, we are able to detect extended NLR emission out to several kpc scales in both QSOs by subtracting the scaled central spectrum from outer spectra. In contrast to the nuclear spectrum, which shows a prominent blue wing and a broad line profile of the [O III] line, the extended emission reveals no clear signs of large scale outflows. Exploiting the wide wavelength range, we determine the radial change of the gas properties in the NLR, i.e., gas temperature, density, and ionization parameter, and compare them with those of Seyfert galaxies and type-II QSOs. The QSOs have higher nuclear temperature and lower electron density than Seyferts, but show no significant difference compared to type-II QSOs, while the ionization parameter decreases with radial distance, similar to the case of Seyfert galaxies. For PG1012+008, we determine the stellar velocity dispersion of the host galaxy. Combined with the black hole mass, we find that the luminous radio-quiet QSO follows the local M_BH-sigma* relation of active galactic nuclei.Comment: 7 pages, 5 figures, accepted for publication in Ap