A survey: Knowledge about breast cancer and health beliefs towards screening practice among menopausal and postmenopausal women

Breast cancer is a major health problem with high mortality in women worldwide and has become the third most prevalent disease among women in Hong Kong. Knowledge about breast cancer is closely related to health beliefs towards screening practices for breast cancer. This study examined knowledge about breast cancer and breast cancer screening (BCS) beliefs among menopausal and postmenopausal women. A total of 213 eligible women, mostly aged 55 to 60, who were housewives or retired and were educated at secondary school level or above, were selected. A survey using the Chinese Breast Cancer Screening Beliefs (CBCSB) questionnaire was conducted. The results revealed that menopausal and postmenopausal women had better health beliefs towards breast cancer screening practices. Education was found to be positively associated with attitudes of BCS health beliefs. It indicates that education can affect attitudes towards breast cancer screening practice. Most of the women presented inadequate knowledge and they wished to receive more information about breast cancer although they were well-educated. It is important to note that knowledge about breast cancer cannot be effectively delivered to the at-risk women. In addition, menopausal and postmenopausal women can be more likely to seek more information about the effectiveness and side effects of the medication for breast cancer. Therefore, treatment about effectiveness, side effects, and prices ought to be included in current educational programs and healthcare services in the promotion schemes. Healthcare professionals should also pay more attention to better BCS practices in community-based educational programs with information on preventive measures for breast cancer to menopausal and postmenopausal women, particularly to those in lower socioeconomic classes

A survey of the perceived lifestyle risks of breast cancer in menopausal and postmenopausal women in Hong Kong

Breast cancer ranks as the most common cause of cancer death in women. If menopausal and postmenopausal women know the lifestyle risks associated with breast cancer and its preventive measures, they will make appropriate choices in order to enjoy their life and have a better chance of preventing this disease. This study attempted to explore perceived beliefs with regard to the lifestyle risks associated with breast cancer among menopausal and postmenopausal women in Hong Kong. A survey was designed that used a self-reporting questionnaire to assess the perceived beliefs of 223 women. Results showed that more than half of the participants held misconceptions about lifestyle breast cancer risks. Only those women who were well-educated and were worried about having breast cancer performed breast screening for cancer. The findings of this study suggest that health care professionals should channel resources to educate menopausal and postmenopausal women about the risks of breast cancer and to promote awareness of breast wellness and the value of breast cancer screening

Menopausal-specific quality of life among women in Hong Kong

This study aimed to explore the menopausal-specific quality of life and assess its relationship with the sociodemographic characteristics in menopausal and post-menopausal women in Hong Kong. A cross-sectional survey was conducted with 218 women aged between 45 and 80 or over. The quality of life was assessed by Menopause-Specific Quality of Life Questionnaire (MENQOLTM). Results showed that the mean scores for vasomotor domain: 2.59 ± 1.71; psycho-social domain: 2.77 ± 1.39; physical domain: 2.89 ± 1.23 and sexual domain 2.60 ± 1.16. The physical domain had the highest score in menopausal and post-menopausal women. Univariate analysis demonstrated that younger and less educated working post-menopausal women perceive lower quality of life. Our findings suggest that menopausal-related symptoms affect the quality of life

Dielectric and pyroelectric properties of lead zirconate titanate/polyurethane composties

Author name used in this publication: K. S. LamAuthor name used in this publication: Y. W. WongAuthor name used in this publication: L. S. TaiAuthor name used in this publication: Y. M. PoonAuthor name used in this publication: F. G. Shin2004-2005 > Academic research: refereed > Publication in refereed journalVersion of RecordPublishe

Integrating Blended Learning in Global Energy Education: Efficacy Evaluation & Insights from the 3D Energy Project Pilot

The rapid paradigm shifts in the global energy industry has emphasize a great need for a workforce that is well-equipped to combat its multifaceted challenges. Although blended learning models have become more common in numerous educational domains, their role in global energy education is not very well established. This paper focuses on evaluating blended learning within the context of the Decarbonisation, Decentralisation, and Digitalisation (3D) Energy Project to further our identification and understanding of a sustainable global energy education learning model. In this research, a novel learning programme involving a physical summit coupled with an online microcredential course, was introduced. This programme conducted a pilot study, which involved a group of postgraduate and final year undergraduate students from Malaysia, Vietnam, and China. Using quantitative and qualitative feedback, this paper sought to assess the summit’s efficacy in fostering international collaborations and broadening participants’ perspectives on energy challenges. Our principal findings indicate that participants greatly valued the opportunity for cross-cultural interactions, gained a deeper comprehension of energy-related topics, and found the course structure to be beneficial. Furthermore, the feedback revealed certain areas for improvement, such as additional language assistance and an extension to the physical summit for more in-depth interactions between countries. To summarise, the programme’s blended learning approach highlighted it’s potential for the future of global energy education

APC-targeted proinsulin expression inactivates insulin-specific memory CD8+ T cells in NOD mice

Type 1 diabetes (T1D) results from T-cell-mediated autoimmune destruction of pancreatic β cells. Effector T-cell responses emerge early in disease development and expand as disease progresses. Following β-cell destruction, a long-lived T-cell memory is generated that represents a barrier to islet transplantation and other cellular insulin-replacement therapies. Development of effective immunotherapies that control or ablate β-cell destructive effector and memory T-cell responses has the potential to prevent disease progression and recurrence. Targeting antigen expression to antigen-presenting cells inactivates cognate CD8+ effector and memory T-cell responses and has therapeutic potential. Here we investigated this in the context of insulin-specific responses in the non-obese diabetic mouse where genetic immune tolerance defects could impact on therapeutic tolerance induction. Insulin-specific CD8+ memory T cells transferred to mice expressing proinsulin in antigen-presenting cells proliferated in response to transgenically expressed proinsulin and the majority were rapidly deleted. A small proportion of transferred insulin-specific Tmem remained undeleted and these were antigen-unresponsive, exhibited reduced T cell receptor (TCR) expression and H-2Kd/insB15-23 tetramer binding and expressed co-inhibitory molecules. Expression of proinsulin in antigen-presenting cells also abolished the diabetogenic capacity of CD8+ effector T cells. Therefore, destructive insulin-specific CD8+ T cells are effectively inactivated by enforced proinsulin expression despite tolerance defects that exist in diabetes-prone NOD mice. These findings have important implications in developing immunotherapeutic approaches to T1D and other T-cell-mediated autoimmune diseases

Predictors of treatment outcome in patients treated with radical chemoradiotherapy for stage III Non-small Cell Lung Cancer

Proffered SessionBACKGROUND: Chemoradiation has been well established as standard treatment for stage III non-small cell lung cancer (NSCLC). Previous studies have shown that the tumour size as well as its metabolic activity predict treatment outcome after definitive treatment for early-stage disease. We would like to investigate if there are any clinical and metabolic predictors of treatment outcome for stage III NSCLC after chemoradiation. PATIENTS AND METHODS: 56 consecutive patients (46 males and 10 females) treated with radical concurrent chemoradiation for their stage IIIA (n=21) and IIIB (n=35) (AJCC 7th edition) unresectable non-small cell lung cancer between July 2006 to February 2012 were retrospectively reviewed. 42 patients had positron emission tomography with integrated computed tomography (PET-CT) scan performed at diagnosis. Of which 14 patients also had PET-CT scan after induction chemotherapy and before concurrent chemoradiation. All received concurrent chemoradiation +/- induction ...postprin

Comparison of post-treatment plasma EBV DNA with nasopharyngeal biopsy in patients after radical (chemo) radiotherapy for non-metatatic nasopharyngeal cancer

This journal suppl. entitled: Proceedings of the American Society for Radiation Oncology 56th Annual Meeting, ASTRO's 56th Annual Meeting ... 2014Oral Scientific SessionPURPOSE/OBJECTIVE(S): Random nasopharyngeal biopsy after completion of intensity-modulated radiation therapy (IMRT) for non-metastatic nasopharyngeal cancer (NPC) is routinely practiced in Hong Kong to confirm local remission. Plasma EBV DNA is proven an accurate marker for NPC. We carried out a prospective study comparing the correlation between post-IMRT nasopharyngeal biopsy and EBV DNA, to investigate if EBV DNA can substitute biopsy to confirm local remission. MATERIALS/METHODS: Patients with non-metastatic NPC treated with definitive (chemo) IMRT diagnosed between January 2011 and March 2013 were recruited. After baseline workup ...postprin

Factors associated with grade 1 hypertension: implications for hypertension care based on the Dietary Approaches to Stop Hypertension (DASH) in primary care settings

Background: A Reference Framework for Hypertension Care was recently developed by Hong Kong government to emphasise the importance of primary care for subjects with high blood pressure (BP). The Dietary Approaches to Stop Hypertension (DASH) interventional regime was recommended for patients aged 40–70 years with grade 1 hypertension (having systolic BP of 140-159 mmHg and/or diastolic BP of 90-99 mmHg). This study explored factors associated with grade 1 hypertension among subjects screened in primary care settings. Methods: The study sample consisted of community dwellers (N = 10,693) enrolled in a primary care programme in which participants overall had similar characteristics when compared to the Hong Kong population census. Invitation phone calls were given by trained researchers to a randomly selected subjects (N = 2,673, [50% of total subjects aged 40–70 years]) between January and June 2013. BP and body mass index (BMI) were measured by trained clinical professionals according to a standard protocol. Interviewer-administered survey questionnaires were used to collect self-report information on socio-demographics, family history, and lifestyle characteristics. Multiple logistic regression analysis was performed to explore factors associated with grade 1 hypertension. Adjusted odds ratios (aORs) were estimated with 95% confidence intervals (CI). Results A total of 679 out of 2,673 subjects agreed to participate in the screening and completed the baseline assessment (100% completion rate), among which, 320 subjects (47.1%, [320/679]) were grade 1 hypertensive. Unhealthy diet (aOR = 2.19, 95%CI 1.04-4.62), irregular meals (aOR = 1.47, 95%CI 1.11-1.95), BMI >27.5 kg/m2 (aOR = 1.87, 95%CI 1.53-2.27), duration of cigarette smoking (aOR = 1.83 per year), increased daily cigarette consumption (aOR = 1.59 per pack [20 cigarettes per pack]), duration of alcohol drinking (aOR = 1.65 per year), and higher frequency of weekly binge drinking (aOR = 1.87 per occasion) were independently associated with grade 1 hypertension. The increase in the number of risk factors combined significantly correlated with higher predicted probability of grade 1 hypertension. Conclusions: Dietary-intake factors were significantly associated with grade 1 hypertension, echoing the recommendation in the Reference Framework on incorporating dietary-related intervention based on the DASH approach for hypertension care in primary care settings. The association between aggregate risk factors and grade 1 hypertension should also be taken into consideration in long-term preventive strategy