26 research outputs found
Influence of phenobarbital on hormone release after insulin induced hypoglycemia
SCOPUS: NotDefined.jinfo:eu-repo/semantics/publishe
Enhanced ACTH and blunted cortisol responses to corticotropin-releasing factor in idiopathic panhypopituitarism
SCOPUS: ar.jinfo:eu-repo/semantics/publishe
Reproducibility of plasma growth hormone determinations between different laboratories
info:eu-repo/semantics/publishe
Puberté précoce transitoire
We report here the case of an 8ζ yr old girl suffering from a dramatic explosive puberty. The symptoms disappeared spontaneously three months later. Investigations demonstrated the existence of autonomous oestrogen secretion, probably by a transient follicular ovarian cyst.SCOPUS: NotDefined.jinfo:eu-repo/semantics/publishe
Evolution of the Δ4-adrenal androgens responsiveness in childhood during insulin test
Serum 11-β-hydroxy-androstenedione (11OHAD), androstenedione (AD) and cortisol (F) were estimated during an i.v. insulin test in 2 large groups of normal prepubertal children and in normal adults. The results revealed that the basal level and responsiveness of AD were much lower in both groups of children than in adults whereas the corresponding 11OHAD data were similar or superior to those of adults. This suggests that during childhood the limited amount of adrenal AD is preferentially switched to the 11-hydroxylation step. Comparison of hormonal data observed in adults after i.v. insulin (mild ACTH stimulation) and a maximal stimulating dose of synacthen showed that the sensitivity of Δ4-3 keto-androgens pathway is inferior to that of F.SCOPUS: ar.jinfo:eu-repo/semantics/publishe
Kinetics of plasma corticosteroids during metyrapone infusion in man
The effect of metyrapone on plasma kinetics of cortisol (F), 11-deoxycortisol (S), corticosterone (B), 11-deoxycorticosterone (DOC), aldosterone (Aldo) and 17 hydroxyprogesterone (17 OHP) was studied in ten normal prepubertal children intravenously infused with the drug (1 gm/1.73 m2 body surface area in 4 h). Similar falls in F, B and Aldo were observed during the first hour expressing similar sensitivity of the 11 hydroxylases to the drug. The effect of the compensatory increase of endogenous ACTH could be detected after 1 hour by the rise in 17 OHP. However the concentrations of the 11-hydroxy compounds, F, B and Aldo, remained low throughout the infusion period. From the second hour onwards, facilitation of the synthesis of DOC was noticed. After the end of infusion, the levels of the precursors decreased and F and B were restored to initial values. Also remained low probably due to the inhibitory effect of the elevated DOC on the renin-angiotensin system.SCOPUS: ar.jFLWNAinfo:eu-repo/semantics/publishe
A direct radio-immunoassay for plasma Δ4-androstenedione. Application to children
A RIA for the estimation of Δ4-androstenedione in human plasma without chromatographie purification is analyzed. Sensitivity, accuracy, precision and specificity are shown to be, at least, equivalent to those of methods involving chromatography. © 1979.SCOPUS: ar.jinfo:eu-repo/semantics/publishe