26 research outputs found

    Influence of phenobarbital on hormone release after insulin induced hypoglycemia

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    SCOPUS: NotDefined.jinfo:eu-repo/semantics/publishe

    Treatment of cryptorchidism

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    SCOPUS: ar.jinfo:eu-repo/semantics/publishe

    Reproducibility of plasma growth hormone determinations between different laboratories

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    info:eu-repo/semantics/publishe

    Puberté précoce transitoire

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    We report here the case of an 8ζ yr old girl suffering from a dramatic explosive puberty. The symptoms disappeared spontaneously three months later. Investigations demonstrated the existence of autonomous oestrogen secretion, probably by a transient follicular ovarian cyst.SCOPUS: NotDefined.jinfo:eu-repo/semantics/publishe

    Evolution of the Δ4-adrenal androgens responsiveness in childhood during insulin test

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    Serum 11-β-hydroxy-androstenedione (11OHAD), androstenedione (AD) and cortisol (F) were estimated during an i.v. insulin test in 2 large groups of normal prepubertal children and in normal adults. The results revealed that the basal level and responsiveness of AD were much lower in both groups of children than in adults whereas the corresponding 11OHAD data were similar or superior to those of adults. This suggests that during childhood the limited amount of adrenal AD is preferentially switched to the 11-hydroxylation step. Comparison of hormonal data observed in adults after i.v. insulin (mild ACTH stimulation) and a maximal stimulating dose of synacthen showed that the sensitivity of Δ4-3 keto-androgens pathway is inferior to that of F.SCOPUS: ar.jinfo:eu-repo/semantics/publishe

    Kinetics of plasma corticosteroids during metyrapone infusion in man

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    The effect of metyrapone on plasma kinetics of cortisol (F), 11-deoxycortisol (S), corticosterone (B), 11-deoxycorticosterone (DOC), aldosterone (Aldo) and 17 hydroxyprogesterone (17 OHP) was studied in ten normal prepubertal children intravenously infused with the drug (1 gm/1.73 m2 body surface area in 4 h). Similar falls in F, B and Aldo were observed during the first hour expressing similar sensitivity of the 11 hydroxylases to the drug. The effect of the compensatory increase of endogenous ACTH could be detected after 1 hour by the rise in 17 OHP. However the concentrations of the 11-hydroxy compounds, F, B and Aldo, remained low throughout the infusion period. From the second hour onwards, facilitation of the synthesis of DOC was noticed. After the end of infusion, the levels of the precursors decreased and F and B were restored to initial values. Also remained low probably due to the inhibitory effect of the elevated DOC on the renin-angiotensin system.SCOPUS: ar.jFLWNAinfo:eu-repo/semantics/publishe

    TSH response to TRH according to age

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    Abstractinfo:eu-repo/semantics/publishe

    A direct radio-immunoassay for plasma Δ4-androstenedione. Application to children

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    A RIA for the estimation of Δ4-androstenedione in human plasma without chromatographie purification is analyzed. Sensitivity, accuracy, precision and specificity are shown to be, at least, equivalent to those of methods involving chromatography. © 1979.SCOPUS: ar.jinfo:eu-repo/semantics/publishe
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