Cortisol awakening response over the course of humanitarian aid deployment: A prospective cohort study

Alastair Ager - ORCID 0000-0002-9474-3563 https://orcid.org/0000-0002-9474-3563Added VoR 2021-01-05Background: Internationally deployed humanitarian aid (HA) workers are routinely confronted with potentially traumatic stressors. However, it remains unknown whether HA deployment and related traumatic stress are associated with long-term changes in hypothalamic-pituitary-adrenal (HPA) axis function. Therefore, we investigated whether cortisol awakening response (CAR) decreased upon deployment and whether this was moderated by previous and recent trauma exposure and parallel changes in symptom severity and perceived social support.Methods: In this prospective study, n=86 HA workers (68% females) completed questionnaires regarding trauma exposure, posttraumatic stress disorder (PTSD), anxiety and depressive symptoms and perceived social support, as well as salivary cortisol assessments at awakening and 30 minutes post-awakening at before, early and 3-6 months post-deployment.Results: Linear mixed models showed significantly decreased CAR (b(SE)=-.036(.011), p=.002) and awakening cortisol over time (b(SE)=-.007(.003), p=.014). The extent of awakening cortisol change was significantly moderated by interactions between previous and recent trauma exposure. Also, a steeper awakening cortisol decrease was significantly associated with higher mean anxiety and PTSD symptoms across assessments. No significant effects were found for social support.Conclusions: We observed attenuated CAR and awakening cortisol upon HA deployment, with a dose-response effect between trauma exposure before and during the recent deployment on awakening cortisol. Awakening cortisol change was associated with PTSD and anxiety symptom levels across assessments. Our findings support the need for organizational awareness that work-related exposures may have long-lasting biological effects. Further research assessing symptoms and biological measures in parallel is needed to translate current findings into guidelines on the individual level.This work was funded by the US Centers for Disease Control and Prevention and the Antares Foundation through a cooperative agreement [Grant Number: 5U01EH000217]; The first author Yulan Qing is financially supported by the Chinese Scholarship Council Grant for her Ph.D. (NO. 201504910771). Additionally, Mirjam van Zuiden was supported by a Veni grant from the Netherlands organization for Health research and Development (ZonMw, grant no. 91617037). The funding source had no role in the design or execution of the research.https://doi.org/10.1080/20008198.2020.181664911pubpub

Psychological Distress, Depression, Anxiety, and Burnout among International Humanitarian Aid Workers: A Longitudinal Study

Background International humanitarian aid workers providing care in emergencies are subjected to numerous chronic and traumatic stressors. Objectives To examine consequences of such experiences on aid workers' mental health and how the impact is influenced by moderating variables. Methodology We conducted a longitudinal study in a sample of international non-governmental organizations. Study outcomes included anxiety, depression, burnout, and life and job satisfaction. We performed bivariate regression analyses at three time points. We fitted generalized estimating equation multivariable regression models for the longitudinal analyses. Results Study participants from 19 NGOs were assessed at three time points: 212 participated at pre-deployment; 169 (80%) post-deployment; and 154 (73%) within 3-6 months after deployment. Prior to deployment, 12 (3.8%) participants reported anxiety symptoms, compared to 20 (11.8%) at post-deployment (p-_=-_00027); 22 (10.4%) reported depression symptoms, compared to 33 (19.5%) at post-deployment (p-_=-_00117) and 31 (20.1%) at follow-up (p-_=-_.00083). History of mental illness (adjusted odds ratio [AOR] 4.2; 95% confidence interval [CI] 145-1250) contributed to an increased risk for anxiety. The experience of extraordinary stress was a contributor to increased risk for burnout depersonalization (AOR 1.5; 95% CI 1.17-1.83). Higher levels of chronic stress exposure during deployment were contributors to an increased risk for depression (AOR 11; 95% CI 102-1.20) comparing post- versus pre-deployment, and increased risk for burnout emotional exhaustion (AOR 1.1; 95% CI 1.04-1.19). Social support was associated with lower levels of depression (AOR 09; 95% CI 084-095), psychological distress (AOR-_=-_0.9; [CI] 0.85-0.97), burnout lack of personal accomplishment (AOR 095; 95% CI 091-098), and greater life satisfaction (p-_=-_0.0213). Conclusions When recruiting and preparing aid workers for deployment, organizations should consider history of mental illness and take steps to decrease chronic stressors, and strengthen social support networks.sch_iih7pub4233pub

Emotional Anguish at Work: The Mediating Role of Perceived Rejection on Workgroup Mistreatment and Affective Outcomes

In this study, the authors pay particular attention to mistreatment directed toward an organizational member from fellow workgroup members. The study contributes to the growing body of literature that examines the mistreatment of employees in the workplace. The authors propose that mistreatment by the workgroup would contribute to feelings of rejection, over and above mistreatment by the supervisor. In addition, the authors tested the mediating role of perceived rejection between workgroup mistreatment and affective outcomes such as depression and organization-based self-esteem. Part-time working participants (N = 142) took part in the study, which required them to complete a questionnaire on workplace behaviors. Results indicated that workgroup mistreatment contributed additional variance to perceived rejection over and above supervisory mistreatment when predicting depression and organization-based self-esteem. The results also indicated that perceived rejection mediates the relationship between mistreatment and affective outcomes. Results are discussed and implications for research and practice are considered

[In Press] It’s about time! : identifying and explaining unique trajectories of solidarity-based collective action to support people in developing countries

Social change occurs over years and decades, yet we know little about how people sustain, increase or diminish their actions over time, and why they do so. This article examines diverging trajectories of solidarity-based collective action to support people in developing nations more than 5 years. We suggest that sustained, diminished, and/or increased action over time will be predicted by identification as a supporter, group efficacy beliefs, and discrete emotions about disadvantage. Latent Growth Mixture Models (N = 483) revealed two trajectories with unique signatures: an activist supporter trajectory with a higher intercept and weakly declining action; and a benevolent supporter trajectory with a lower intercept but weakly increasing action. The activist trajectory was predicted by social identification, outrage, and hope, whereas the benevolent supporter trajectory was predicted by sympathy. The results highlight the role of combinations of emotions and the need for person-centered longitudinal methods in collective action research

Vegetarian, vegan, activist, radical: using latent profile analysis to examine different forms of support for animal welfare

There are many different ways that people can express their support for the animals that exist in factory farms. This study draws on insights from the social identity approach, and adopts novel methods (latent profile analysis [LPA]) to examine the qualitatively different subgroups or profiles that comprise broader community positions on this issue. North American participants (N = 578) completed measures of the frequency with which they engaged in 18 different animal welfare actions. LPA identified 3 meaningful profiles: ambivalent omnivores (n = 410; people who occasionally limited their consumption of meat/animal products), a lifestyle activist group (n = 134; limited their consumption of animal/meat products and engaged in political actions), and a vegetarian radical group (n = 34; strictly limited their consumption of animal/meat products and engaged in both political and radical actions). Membership of the 3 populations was predicted by different balances of social identities (supporter of animal welfare, vegan/vegetarian, solidarity with animals), and markers of politicization and/or radicalization. Results reveal the utility of adopting person-centred methods to study political engagement and extremism generally, and highlight heterogeneity in the ways that people respond to the harms perpetrated against animals

Decreased awakening cortisol over the course of humanitarian aid deployment is associated with stress-related symptoms: A prospective cohort study

Ager, Alastair - ORCID 0000-0002-9474-3563 https://orcid.org/0000-0002-9474-3563Item not available in this repository.Background: Internationally deployed humanitarian aid (HA) workers are at risk for traumatic and chronic stress, and consequently stress-related psychopathology. Therefore, HA deployment may lead to long-term changes in neuroendocrine stress reactivity. Objective: We investigated whether awakening cortisol changed upon deployment, and whether this was associated with lifetime childhood and adulthood traumatic stressors, current deployment-related traumatic and chronic stressors and within-person changes in stress-related symptomatology upon deployment. Method: From a prospective study among expatriate HA workers (n = 214) from 19 international NGOs, we included n = 86 participants (68% females, 33 ± 8 years) who completed questionnaires and cortisol assessments at three points: pre-deployment, early post-deployment and 3–6 months post-deployment. At each assessment, cortisol parameters were calculated from two saliva samples: at awakening and 30 minutes post-awakening. Results: Linear mixed models showed significant decreased awakening cortisol over time (bs: −.036 [SE = .011] to −.008 [SE = .003], all ps < .007). Cortisol was significantly predicted by three-way interactions between lifetime stressors, deployment stressors and time, with the smallest decrease over time in those with limited lifetime and current stressors (all ps < .05). The change in cortisol was no longer significant upon inclusion of stress-related symptoms in the model. Moreover, a sharper cortisol decrease was significantly associated with higher anxiety (p = .004) and PTSD symptoms (p = .049) across assessments. Conclusions: This is the first study indicating decreased awakening cortisol after HA deployment. The exact decrease within participants depended on the amount of lifetime and current stressors. Importantly, when taking changes in stress-related symptomatology into account, we found these accounted for the attenuated awakening cortisol.https://doi.org/10.1080/20008198.2019.161383410pubpubSup

Predictors of Hepatitis B screening and vaccination status of young psychoactive substance users in informal settlements in Kampala, Uganda.

BackgroundYoung psychoactive substance users exhibit high-risk behaviours such as unprotected sexual intercourse, and sharing needles and syringes, which increases their risk of Hepatitis B infection. However, there is limited evidence of screening, and vaccination status of this subgroup. The aim of this study was to establish the predictors of screening and completion of the hepatitis B vaccination schedule.MethodsA cross-sectional study using respondent driven sampling was used to enrol respondents from twelve out of fifty-seven informal settlements in Kampala city. Data were collected using an electronic structured questionnaire uploaded on the KoboCollect mobile application, and analysed using Stata version 14. A "modified" Poisson regression analysis was done to determine the predictors of screening while logistic regression was used to determine the predictors of completion of the Hepatitis B vaccination schedule.ResultsAbout 13.3% (102/768) and 2.7% (21/768) of the respondents had ever screened for Hepatitis B, and completed the Hepatitis B vaccination schedule respectively. Being female (aPR 1.61, 95% CI: 1.11-2.33), earning a monthly income >USD 136 (aPR 1.78, 95% CI: 1.11-2.86); completion of the Hepatitis B vaccination schedule (aPR 1.85, 95% CI: 1.26-2.70); lack of awareness about the recommended Hepatitis B vaccine dose (aPR 0.43, 95% CI: 0.27-0.68); and the belief that the Hepatitis B vaccine is effective in preventing Hepatitis B infection (aPRR 3.67, 95% CI: 2.34-5.73) were associated with "ever screening" for Hepatitis B. Knowledge of the recommended Hepatitis B vaccine dose (aOR 0.06, 95% CI: 0.01-0.35); "ever screening" for hepatitis B (aOR 9.68, 95% CI: 2.17-43.16) and the belief that the hepatitis B vaccine is effective in preventing Hepatitis B infection (aOR 11.8, 95% CI: 1.13-110.14) were associated with completion of the hepatitis B vaccination schedule.ConclusionsOur findings indicate a low prevalence of Hepatitis B screening and completion of the Hepatitis B vaccination schedule among young psychoactive substance users in informal settings. It is evident that lack of awareness about Hepatitis B is associated with the low screening and vaccination rates. We recommend creation of awareness of Hepatitis B among young people in urban informal settlements