853 research outputs found

    The Impact of Mental Illness Status on the Length of Jail Detention and the Legal Mechanism of Jail Release

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    Objective: This analysis investigated whether persons with serious mental illnesses have longer jail detentions than other detainees and whether they are released by different legal mechanisms. Methods: Jail records and mental health service records from a Medicaid database were matched for all admissions to the Philadelphia jail system in 2003. Survival analysis techniques were used to compare length of jail stays of persons with and without serious mental illnesses (N=24,290). Serious mental illness was defined as a diagnosis either in the schizophrenia spectrum (DSM-IV code 295.XX) or of a major affective disorder (DSMIV code 296.XX) recorded in Medicaid records (2001–2003). Mechanisms of release were also examined for those with release dates before September 1, 2005 (N=20,573) Results: Just over 50% of the 1,457 persons with serious mental illnesses were released from jail within 30 days of incarceration, compared with 56% of the other detainees. Mental illness status was not found to be a significant predictor of longer detentions. Forty-nine percent of those with serious mental illnesses were released from jails through unpredictable release mechanisms, such as bail, release from court, or withdrawal of a bench warrant, whereas only 19% were released through mechanisms that had release dates that allowed adequate time for discharge planning. Conclusions: The findings suggest that reentry programs and other jail-based interventions for persons with mental illnesses should ensure that they have the capacity to rapidly identify and serve clients with shorter and more unpredictable stays or risk not being responsive to the needs of a substantial proportion of this population

    Prostanthera tallowa: a new species from New South Wales, Australia

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    Prostanthera tallowa B.J.Conn & T.C.Wilson (Lamiaceae) is possibly a vulnerable species that is here described from the Central Coast region of New South Wales, Australia

    Prostanthera elisabethae (Lamiaceae, tribe Westringieae), a new species from northern New South Wales, Australia

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    The new species Prostanthera elisabethae B.J.Conn & T.C.Wilson (Lamiaceae) is described for the first time. The distribution and abundance of this species is inadequately known, having only been collected from near Ashby, on the North Coast of New South Wales, Australia. Although very similar to P. linearis, this taxon is different by having longer pedicels. Measurements and figures accompany the description provided here to substantiate this as a new species

    Two new species of Prostanthera (Lamiaceae) in New South Wales

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    Prostanthera gilesii and P. makinsonii (Lamiaceae) are described as new for New South Wales, Australia. These descriptions are accompanied by illustrations and general notes, including distribution and conservation status. A new identification key is provided for the species of Prostanthera in New South Wales

    RADseq as a valuable tool for plants with large genomes-a case study in cycads

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    Full genome sequencing of organisms with large and complex genomes is intractable and cost ineffective under most research budgets. Cycads (Cycadales) represent one of the oldest lineages of the extant seed plants and, partly due to their age, have incredibly large genomes up to ~60 Gbp. Restriction site-associated DNA sequencing (RADseq) offers an approach to find genome-wide informative markers and has proven to be effective with both model and nonmodel organisms. We tested the application of RADseq using ezRAD across all 10 genera of the Cycadales including an example data set of Cycas calcicola representing 72 samples from natural populations. Using previously available plastid and mitochondrial genomes as references, reads were mapped recovering plastid and mitochondrial genome regions and nuclear markers for all of the genera. De novo assembly generated up to 138,407 high-depth clusters and up to 1,705 phylogenetically informative loci for the genera, and 4,421 loci for the example assembly of C. calcicola. The number of loci recovered by de novo assembly was lower than previous RADseq studies, yet still sufficient for downstream analysis. However, the number of markers could be increased by relaxing our assembly parameters, especially for the C. calcicola data set. Our results demonstrate the successful application of RADseq across the Cycadales to generate a large number of markers for all genomic compartments, despite the large number of plastids present in a typical plant cell. Our modified protocol was adapted to be applied to cycads and other organisms with large genomes to yield many informative genome-wide markers

    Nomenclatural changes in Coleus and Plectranthus (Lamiaceae): a tale of more than two genera

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    A synopsis of the genera Coleus Lour, Equilabium A.J.Paton, Mwany. & Culham and Plectranthus L’Hér. (Lamiaceae, Tribe Ocimeae, Subtribe Plecranthinae) is presented. Generic delimitation follows a recently published molecular phylogeny which identified Coleus as the sister of the remaining genera of Subtribe Plectranthinae; Plectranthus as sister to Tetradenia Benth. and Thorncroftia N.E.Br., and a separate phylogenetically distinct genus Equilabium comprising species previously placed in Plectranthus. In this treatment, 294 species of Coleus, 42 of Equilabium, and 72 of Plectranthus are recognized. All but one of the combinations in Equilabium are new as only the genus and type species have been previously published. Two-hundred and twelve names are changed to combinations in Coleus from Plectranthus, Pycnostachys Hook. and Anisochilus Benth

    Molecular phylogenetics reveals a new species of Prostanthera from tropical Queensland with links to more southerly taxa

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    Prostanthera eungella B.J.Conn & K.M.Proft (Lamiaceae) is described as a new species from the South Kennedy botanical region of northern Queensland. Concatenated nuclear (ETS) and chloroplast (trnH–psbA) sequence data for 38 species of Prostanthera were analysed using maximum-likelihood and Bayesian-inference methods. These combined data recovered P. eungella as part of a polytomy that included P. galbraithiae, P. howelliae¸ and a P. tallowa + P. lasianthos clade. A detailed description, photograph of holotype specimen, and distribution map of P. eungella are provided

    Sperm Quality of Hatchery-Reared Lake Trout Throughout the Spawning Season

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    The objective of this study was to investigate variation in sperm quality metrics (motility, velocity, linearity, longevity, and density) of hatchery-reared Lake Trout Salvelinus namaycush throughout the spawning season. Seasonal variation in sperm quality was investigated using both a regression and repeated-measures approach. Sperm was collected from the same 16 individuals over four sampling periods, separated by 3-week intervals. Regression analyses showed that 727% of the variation in sperm traits could be explained by seasonal variation, indicating that seasonality can have a significant impact on the quality of sperm. Significant positive linear relationships were found for percent motility and linearity at 5s postactivation. Significant negative quadratic relationships were found for velocity at 5s postactivation, longevity, and density, whereas a positive quadratic relationship was found for linearity at 10s postactivation. Repeated measures ANOVAs showed a significant effect of season for percent motility and linearity at 5 and 10s postactivation, velocity at 10s postactivation, and longevity. Our findings are important for optimizing fertilization protocols for hatchery production and can also be used to understand reproductive biology and ecology of wild Lake Trout stocks. Received March 15, 2012; accepted June 30, 201

    Considerations for legal, ethical, and effective practice in dementia research

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    Dementia represents a potentially overwhelming health burden, both for the UK and worldwide. Addressing this fast-growing issue is a key priority for the government, health service and the public. Advances in care including the development of efficacious disease-modifying, and eventually curative, treatments can only be achieved through effective dementia research. Specifically, research directly involving participants with dementia is essential to further understanding. However, working with cognitively impaired participants with and without capacity to consent to research presents unique ethical and legal challenges. For clinicians and scientists on the frontline of dementia research, scenarios frequently arise that pose such challenges. A lack of guidance for a consistent approach in navigating these scenarios limits researchers’ ability to proceed with confidence. This represents a threat to the rights and wishes of research participants as well as the field at large, as it may lead to studies being unnecessarily terminated or, worse, poor practice. In this article, we take a multiprofessional approach, informed by carer input, to these issues. We review the relevant ethical and legal literature relating to the conduct of non-interventional research studies in patients with dementia. This includes a thorough recap of the Mental Capacity Act (2005), which provides a legal framework in England and Wales for conducting research with participants who lack capacity to consent. We also discuss the important, but sometimes incomplete, role of research ethics committees in guiding researchers. We then present and discuss a series of case vignettes designed to highlight areas of incomplete coverage by existing governance. These vignettes describe theoretical scenarios informed by our own real-word experiences of encountering ethical issues when conducting dementia research. They include scenarios in which participants demonstrate varying degrees of understanding of the research they are involved in and ability to communicate their wishes and feelings. Building on these vignettes, we then provide a checklist for researchers to work through when presented with similar scenarios. This checklist covers the key ethical, legal and practical considerations that we have argued for. Taken together, this article can act as a guide, previously lacking in the literature, for colleagues in the field to enable much needed ethical, legal and effective research

    A conservation genomics workflow to guide practical management actions

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    Owing to decreasing costs and increased efficiency, it is now conceivable that conservation genomic information can be used to improve the effectiveness of recovery programs for many, if not most, threatened plants. We suggest that a simple genomic study be viewed as an initial step in conservation decision-making, as it informs long-term recovery efforts in various ways. We present biodiversity managers and conservation biologists with a simple, standardized workflow for genomic research that can guide efficient collection, analysis and application of genomic information across disparate threatened plants. Using two case studies, ‘Banksia vincentia’ and Daphnandra johnsonii, we demonstrate how a single round of genotyping by sequencing e a one-time cost e produces multiple directly applicable benefits, and how generating genomic information as early as possible can enhance conservation outcomes. We argue for a shift away from asking whether genomic information is needed or justified, and a shift towards consideration of the questions that need to be addressed. Such questions should aimed at cost-effectively guiding multiple practical aspects of a threatened plant’s management plan. The workflow presented here should help relevant stakeholders design a sampling strategy that directly suits their questions and needs
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