Are Urban Consumers in China Ready to Accept Biotech Foods?

Based on a large-scale survey conducted in 11 large and small eastern cities in 2002, this study employs ordered probit models to estimate the effects of demographic and socio-economic variables on the likelihood of biotech food acceptance in China. This study also employs a dichotomous choice model to estimate consumers' mean willingness to pay (WTP) for biotech foods, including soybean oil and insect-resistant biotech rice. This survey reaffirms that Chinese urban consumers had a low awareness of biotechnology. Despite the low level of awareness, a great majority of respondents had favorable or neutral attitudes toward biotech foods. Only 5-15 percent was strongly or relatively opposed to biotech foods. Results from the models suggest that mid- and small-city consumers were more supportive of the use of biotech foods than large-city consumers. In addition, consumers with poorer health were less willing to accept biotech foods. Those consumers who trusted the accuracy of media information were also more willing to accept biotech foods. A majority-60 percent or higher-of the respondents were willing to purchase biotech foods without any price discounts. However, about 20 percent would only accept non-biotech foods. Results of the WTP analysis suggest that the likely price premiums that respondents are willing to pay for non-biotech foods averaged around 23.4 percent in the case of soybean oil and 41.5 percent for rice. Mean WTPs estimated from this study are likely to be overstated due in part to the hypothetical nature of the survey data.biotech foods, ordered probit model, consumer acceptance, willingness to pay, China, Consumer/Household Economics, Research and Development/Tech Change/Emerging Technologies, Q11, Q13,

Consumers' Willingness to Pay for Biotech Foods in China

Based on a large-scale consumer survey, this study employs a semi-double-bounded dichotomous choice model to estimate the mean willingness to pay (WTP) for biotech foods in China. The study also accounts for the effects of respondents' characteristics on the probability of purchasing biotech foods and WTP. Analyses focus on biotech soybean oil and insect-resistant biotech rice.Biotech foods, willingness to pay, China, contingent valuation method, semi-double-bounded dichotomous choice model, Consumer/Household Economics,

Minimally Invasive Ablative Therapies for Definitive Treatment of Localized Prostate Cancer in the Primary Setting

Traditionally, the patient with a new diagnosis of localized prostate cancer faces either radical therapy, in the form of surgery or radiation, or active surveillance. A growing subset of these men may not be willing to accept the psychological burden of active surveillance nor the side effects of extirpative or radiation therapy. Local ablative therapies including cryotherapy, high-intensity focused ultrasound, and vascular-targeted photodynamic therapy have emerged as a means for minimally invasive definitive treatment. These treatments are well tolerated with decreased morbidity in association with improvements in technology; however, long-term oncologic efficacy remains to be determined

Home Away from Home: Diaspora Tourism and Transnational Attachment of Second-Generation Chinese-Americans

Globalization has allowed contemporary immigrants to live in two worlds and maintain virtual and physical contact with their homeland through leisure and diaspora tourism. This study examined the lived experience of second-generation Chinese-Americans as they traveled to their parents’ country of origin and explored the relationship between their transnational homeland attachment and diaspora tourism experience. Using a phenomenological approach, twenty-six second-generation Chinese-Americans who had the experience of traveling in China were interviewed. Four themes were identified from their travel experience: destination image, authenticity, family history, and homeland attachment. Findings revealed how being a secondgeneration immigrant influenced the way they saw and experienced China as both destination and homeland

Presyncope Is Associated with Intensive Care Unit Admission in Emergency Department Patients with Acute Pulmonary Embolism

Introduction: Syncope is common among emergency department (ED) patients with acute pulmonary embolism (PE) and indicates a higher acuity and worse prognosis than in patients without syncope. Whether presyncope carries the same prognostic implications has not been established. We compared incidence of intensive care unit (ICU) admission in three groups of ED PE patients: those with presyncope; syncope; and neither.Methods: This retrospective cohort study included all adults with acute, objectively confirmed PE in 21 community EDs from January 2013–April 2015. We combined electronic health record extraction with manual chart abstraction. We used chi-square test for univariate comparisons and performed multivariate analysis to evaluate associations between presyncope or syncope and ICU admission from the ED, reported as adjusted odds ratios (aOR) with 95% confidence intervals (CI).Results: Among 2996 PE patients, 82 (2.7%) had presyncope and 109 (3.6%) had syncope. ICU admission was similar between groups (presyncope 18.3% vs syncope 25.7%) and different than their non-syncope counterparts (either 22.5% vs neither 4.7%; p<0.0001). On multivariate analysis, both presyncope and syncope were independently associated with ICU admission, controlling for demographics, higher-risk PE Severity Index (PESI) class, ventilatory support, proximal clot location, and submassive and massive PE classification: presyncope, aOR 2.79 (95% CI, 1.40, 5.56); syncope, aOR 4.44 (95% CI 2.52, 7.80). These associations were only minimally affected when excluding massive PE from the model. There was no significant interaction between either syncope or presyncope and PESI, submassive or massive classification in predicting ICU admission.Conclusion: Presyncope appears to carry similar strength of association with ICU admission as syncope in ED patients with acute PE. If this is confirmed, clinicians evaluating patients with acute PE may benefit from including presyncope in their calculus of risk assessment and site-of-care decision-making

Casein kinase iδ mutations in familial migraine and advanced sleep phase.

Migraine is a common disabling disorder with a significant genetic component, characterized by severe headache and often accompanied by nausea, vomiting, and light sensitivity. We identified two families, each with a distinct missense mutation in the gene encoding casein kinase Iδ (CKIδ), in which the mutation cosegregated with both the presence of migraine and advanced sleep phase. The resulting alterations (T44A and H46R) occurred in the conserved catalytic domain of CKIδ, where they caused reduced enzyme activity. Mice engineered to carry the CKIδ-T44A allele were more sensitive to pain after treatment with the migraine trigger nitroglycerin. CKIδ-T44A mice also exhibited a reduced threshold for cortical spreading depression (believed to be the physiological analog of migraine aura) and greater arterial dilation during cortical spreading depression. Astrocytes from CKIδ-T44A mice showed increased spontaneous and evoked calcium signaling. These genetic, cellular, physiological, and behavioral analyses suggest that decreases in CKIδ activity can contribute to the pathogenesis of migraine