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Introduction [special issue: Critical realism in information systems research]
Beyond the Hype: RPA Horizon for Robot-Human Interaction
Medium and big organizations have embraced RPA in the last years bringing to light the high maturity of the technology. Current trends are towards including “human-in-the-loop” which promotes efficient ways for robot-human interaction. This is especially relevant since most real RPA projects require a collaboration between the human and the robot leading to hybrids approaches. The challenges that arise from this line can be addressed by both asynchronous (i.e., landing area or task queues where robots and humans share information) and synchronous
solutions (i.e., human digital augmentation where robots provide immediate support). This paper goes in deep elaborating in these two alternatives by setting the benefits, requirements, and future research lines which are envisioned through industrial experiences. In addition, this work exposes the role of process mining in this journey since it allows for the necessary efficiency in the process analysis, time-to-market reduction, and continuous improvement that this robot-human collaboration requires.Ministerio de Economía y Competitividad TIN2016-76956-C3-2-RJunta de Andalucía CEI-12-TIC02
Adaption of the ex vivo mycobacterial growth inhibition assay for use with murine lung cells.
In the absence of a correlate(s) of protection against human tuberculosis and a validated animal model of the disease, tools to facilitate vaccine development must be identified. We present an optimised ex vivo mycobacterial growth inhibition assay (MGIA) to assess the ability of host cells within the lung to inhibit mycobacterial growth, including Bacille Calmette-Guérin (BCG) and Mycobacterium tuberculosis (MTB) Erdman. Growth of BCG was reduced by 0.39, 0.96 and 0.73 log10 CFU following subcutaneous (s.c.) BCG, intranasal (i.n.) BCG, or BCG s.c. + mucosal boost, respectively, versus naïve mice. Comparatively, a 0.49 (s.c.), 0.60 (i.n.) and 0.81 (s.c. + mucosal boost) log10 reduction in MTB CFU was found. A BCG growth inhibitor, 2-thiophenecarboxylic acid hydrazide (TCH), was used to prevent quantification of residual BCG from i.n. immunisation and allow accurate MTB quantification. Using TCH, a further 0.58 log10 reduction in MTB CFU was revealed in the i.n. group. In combination with existing methods, the ex vivo lung MGIA may represent an important tool for analysis of vaccine efficacy and the immune mechanisms associated with vaccination in the organ primarily affected by MTB disease
Why disease due to Mycobacterium tuberculosis is less common than expected in HIV-positive patients in Edinburgh
AbstractBy December 1993, only five cases of tuberculosis were observed in the 1030 HIV-positive patients in Edinburgh, U.K., although, on the basis of historical tuberculin skin test data, between four and eight new cases of tuberculosis were expected per year. Of 310 HIV-positive patients, none of the 19 (6·1%) who were tuberculin skin test positive had developed tuberculosis after 87 months (average) of follow-up. It is suggested that new or re-infection is a more common cause of tuberculosis in HIV-positive patients than reactivation. Restriction fragment length polymorphism typing of Mycobacterium tuberculosis strains could confirm this hypothesis and support currently suggested additional infection control procedures
Amperometric and spectrophotometric determination of carbaryl in natural waters and commercial formulations
The work presented describes the development
and evaluation of two flow-injection analysis (FIA) systems
for the automated determination of carbaryl in spiked
natural waters and commercial formulations. Samples are
injected directly into the system where they are subjected
to alkaline hydrolysis thus forming 1-naphthol. This product
is readily oxidised at a glassy carbon electrode. The
electrochemical behaviour of 1-naphthol allows the development
of an FIA system with an amperometric detector
in which 1-naphthol determination, and thus measurement
of carbaryl concentration, can be performed. Linear response
over the range 1.0×10–7 to 1.0×10–5 mol L–1, with a
sampling rate of 80 samples h–1, was recorded. The detection
limit was 1.0×10–8 mol L–1. Another FIA manifold was
constructed but this used a colorimetric detector. The methodology
was based on the coupling of 1-naphthol with phenylhydrazine
hydrochloride to produce a red complex which
has maximum absorbance at 495 nm. The response was
linear from 1.0×10–5 to 1.5×10–3 mol L–1 with a detection
limit of 1.0×10–6 mol L–1. Sample-throughput was about
60 samples h–1. Validation of the results provided by the
two FIA methodologies was performed by comparing
them with results from a standard HPLC–UV technique.
The relative deviation was <5%. Recovery trials were also
carried out and the values obtained ranged from 97.0 to
102.0% for both methods. The repeatability (RSD, %) of
12 consecutive injections of one sample was 0.8% and
1.6% for the amperometric and colorimetric systems, respectively
A Method to Improve the Early Stages of the Robotic Process Automation Lifecycle
The robotic automation of processes is of much interest to
organizations. A common use case is to automate the repetitive manual
tasks (or processes) that are currently done by back-office staff
through some information system (IS). The lifecycle of any Robotic Process
Automation (RPA) project starts with the analysis of the process
to automate. This is a very time-consuming phase, which in practical
settings often relies on the study of process documentation. Such documentation
is typically incomplete or inaccurate, e.g., some documented
cases never occur, occurring cases are not documented, or documented
cases differ from reality. To deploy robots in a production environment
that are designed on such a shaky basis entails a high risk. This paper
describes and evaluates a new proposal for the early stages of an RPA
project: the analysis of a process and its subsequent design. The idea is to
leverage the knowledge of back-office staff, which starts by monitoring
them in a non-invasive manner. This is done through a screen-mousekey-
logger, i.e., a sequence of images, mouse actions, and key actions
are stored along with their timestamps. The log which is obtained in
this way is transformed into a UI log through image-analysis techniques
(e.g., fingerprinting or OCR) and then transformed into a process model
by the use of process discovery algorithms. We evaluated this method for
two real-life, industrial cases. The evaluation shows clear and substantial
benefits in terms of accuracy and speed. This paper presents the method,
along with a number of limitations that need to be addressed such that
it can be applied in wider contexts.Ministerio de Economía y Competitividad TIN2016-76956-C3-2-
South Africa's business process outsourcing services sector: Lessons for Western-based client firms
Since 2008, South Africa has become one of the world's upcoming offshore destinations for business process outsourcing (BPO), a market estimated to be worth $US 182 billion globally by 2013. Western-based client firms evaluating South Africa as a BPO destination must consider the country's relative value against alternative locations. Client firms also have a number of engagement models from which to choose, inclucling outsourcing, erecting a captive centre, or acquiring an existing BPO business. The research finds that, for the UK, US, and Australian client companies in this study, South Africa's value proposition is not just based on costs as other locations are often cheaper. South Africa's value proposition is about overall economic value, high quality service and staff, strong cultural compatibility, and a favourable time zone. The findings reveal that South Africa complements the global portfolio for Western-based client firms that already have BPO centres in Inclia, the Philippines, and Eastern Europe. Moreover, whether client firms build or buy services from South Africa, the research identifies clistinctive risks that need to be mitigated by investing in and effectively governing the business processes performed offshore. Finally, from the case study research, this article identifies management lessons for leveraging South Africa's identifiable BPO service advantage
Towards an OpenSource Logger for the Analysis of RPA Projects
Process automation typically begins with the observation of
humans conducting the tasks that will be eventually automated. Sim ilarly, successful RPA projects require a prior analysis of the undergo ing processes which are being executed by humans. The process of col lecting this type of information is known as user interface (UI) logging
since it records the interaction against a UI. Main RPA platforms (e.g.,
Blueprism and UIPath) incorporate functionalities that allow the record ing of these UI interactions. However, the records that these platforms
generate lack some functionalities that large-scale RPA projects require.
Besides, they are only understandable by the proper RPA platforms.
This paper presents an extensible and multi-platform OpenSource UI
logger that generate UI logs in a standard format. This system collects
information from all the computers it is running on and sends it to a
central server for its processing. Treatment of the collected information
will allow the creation of an enriched UI log which can be used, among
others purposes, for smart process analysis, machine learning training,
the creation of RPA robots, or, being more general, for task mining .Ministerio de Economía y Competitividad TIN2016-76956-C3-2-R (POLOLAS)Junta de Andalucía CEI-12-TIC021Centro para el Desarrollo Tecnol´ogico Industrial (CDTI) P011-19/E0
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