12 research outputs found
P53 and CD44 as clinical markers of tumour progression in colorectal carcinogenesis
Get PDFRecent advances in molecular genetics have importantly improved our understanding of the development of colorectal cancer. The present review gives an overview of the clinical value of the tumour-suppressor gene, p53, and the CD44 cell adhesion molecule in colorectal cancer and the pitfalls encountered in the immunohistochemical detection of these proteins. Immunohistochemistry potentially forms a procedure applicable for routine diagnosis and prognostication. Therefore, p53 expression and the independent prognostic importance of CD44v6 expression is given particular emphasis, and other molecular events underlying colorectal carcinogenesis are only mentioned briefl
Cellular distribution of CD44 gene transcripts in colorectal carcinomas and in normal colonic mucosa.
No full textDifferential expression of CD44v6 in metastases of intestinal and diffuse types of gastric carcinoma
No full textRelation between stage, grade, proliferation, and expression of p53 and CD44 in adenomas and carcinomas of the colorectum.
No full textExpression of CD44H and CD44v3 in normal oesophagus, Barrett mucosa and oesophageal carcinoma.
No full textIsolation and characterisation of antibodies which specifically recognise the peptide encoded by exon 7 (v2) of the human CD44 gene
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