2,178 research outputs found

    #dssf16+1: Library-led Digital Scholarship for Undergraduates at a Small Institution

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    Librarian R.C. Miessler and Digital Scholarship Fellows Keira Koch, Julia Wall, and Lauren White were invited to speak to at the Pennsylvania Library Association, College and Research Division, Spring Conference about their experiences with the first cohort of the Digital Scholarship Summer Fellowship

    #dssf16: Library-led Digital Scholarship for Undergraduates at a Small Institution

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    In the summer of 2016, Gettysburg Collegeā€™s Musselman Library piloted the Digital Scholarship Summer Fellowship (DSSF), a library-led, student-centered introduction to digital scholarship. The Fellowship, a 10-week, paid, summer program for rising sophomores and juniors, is programmatic, based on a curriculum designed to introduce the student fellows to digital tools, project management, documentation, and the philosophy behind digital scholarship. The Fellowship aimed to create a digital scholarship community of practice at Gettysburg College, collaborating with educational technologists and faculty engaged in digital scholarship to support the needs of the first cohort; in addition, the Fellowship supported the digital scholarship activities of students participating in other summer research programs. R.C. Miessler, coordinator of the Digital Scholarship Summer Fellowship, will discuss the creation, development, implementation, and future of the program. The student fellows, Keira Koch, Julia Wall, and Lauren White, will reflect on their experience and present the digital projects they created

    Early exposure of bay scallops (Argopecten irradians) to high CO2 causes a decrease in larval shell growth

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    Ā© The Author(s), 2013. This article is distributed under the terms of the Creative Commons Attribution License. The definitive version was published in PLoS ONE 8 (2013): e61065, doi:10.1371/journal.pone.0061065.Ocean acidification, characterized by elevated pCO2 and the associated decreases in seawater pH and calcium carbonate saturation state (Ī©), has a variable impact on the growth and survival of marine invertebrates. Larval stages are thought to be particularly vulnerable to environmental stressors, and negative impacts of ocean acidification have been seen on fertilization as well as on embryonic, larval, and juvenile development and growth of bivalve molluscs. We investigated the effects of high CO2 exposure (resulting in pH = 7.39, Ī©ar = 0.74) on the larvae of the bay scallop Argopecten irradians from 12 h to 7 d old, including a switch from high CO2 to ambient CO2 conditions (pH = 7.93, Ī©ar = 2.26) after 3 d, to assess the possibility of persistent effects of early exposure. The survival of larvae in the high CO2 treatment was consistently lower than the survival of larvae in ambient conditions, and was already significantly lower at 1 d. Likewise, the shell length of larvae in the high CO2 treatment was significantly smaller than larvae in the ambient conditions throughout the experiment and by 7 d, was reduced by 11.5%. This study also demonstrates that the size effects of short-term exposure to high CO2 are still detectable after 7 d of larval development; the shells of larvae exposed to high CO2 for the first 3 d of development and subsequently exposed to ambient CO2 were not significantly different in size at 3 and 7 d than the shells of larvae exposed to high CO2 throughout the experiment.This work was funded by a Woods Hole Oceanographic Institution Interdisciplinary Award to Mullineaux & McCorkle; and awards to Mullineaux & White, to McCorkle, and to Cohen & McCorkle through NOAA (National Oceanic and Admosphereic Administration) Sea Grant #NA10OAR4170083. White was funded through a National Defense Science and Engineering Graduate Fellowship through the American Society for Engineering Education

    Outdoor Microplastic Analysis Using Inlet Filters from an NOx Regulatory Air Quality Monitoring Device

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    Atmospheric microplastics (MPs) are a ubiquitous environmental contaminant of emerging concern. Sampling methods provide information relating to surface area concentration and MP characteristics, without direct comparison with routinely measured standard air quality parameters. This study analysed 6 active air samples generated by a local authority as part of their routine air quality monitoring activities. Continuous sampling totalled 10 months, within the city centre of Kingston-upon-Hull. By using Ī¼FTIR analysis, levels of total particles detected using the NOx inlet filters ranged from 5139 Ā± 2843 particles māˆ’2 dayāˆ’1, comprising 1029 Ā± 594 MPs māˆ’2 dayāˆ’1. The controls displayed a mean level of 2.00 Ā± 3.49 MPs. The polymers nylon (32%) and polypropylene, PP (22%) were the most abundant. Small fragments of 47.42 Ā± 48.57 Ī¼m (length) and 21.75 Ā± 13.62 Ī¼m (width) were most common. An increase in MP levels during April 2020 coincided with an increase in PM10 levels. This study used robust procedures to measure MPs in the air by exploiting existing air quality monitoring equipment. Knowing the levels, types, and characteristics of MPs can inform toxicity studies to provide more environmentally relevant exposures, which is urgent now that MPs have been reported in human lung tissu

    Ovarian Cancer Incidence Corrected for Oophorectomy

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    Current reported incidence rates for ovarian cancer may significantly underestimate the true rate because of the inclusion of women in the calculations who are not at risk for ovarian cancer due to prior benign salpingo-oophorectomy (SO). We have considered prior SO to more realistically estimate risk for ovarian cancer. Kentucky Health Claims Data, International Classification of Disease 9 (ICD-9) codes, Current Procedure Terminology (CPT) codes, and Kentucky Behavioral Risk Factor Surveillance System (BRFSS) Data were used to identify women who have undergone SO in Kentucky, and these women were removed from the at-risk pool in order to re-assess incidence rates to more accurately represent ovarian cancer risk. The protective effect of SO on the population was determined on an annual basis for ages 5ā€“80+ using data from the years 2009ā€“2013. The corrected age-adjusted rates of ovarian cancer that considered SO ranged from 33% to 67% higher than age-adjusted rates from the standard population. Correction of incidence rates for ovarian cancer by accounting for women with prior SO gives a better understanding of risk for this disease faced by women. The rates of ovarian cancer were substantially higher when SO was taken into consideration than estimates from the standard population

    Understanding park visitorsā€™ soundscape perception using subjective and objective measurement

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    Environmental noise knows no boundaries, affecting even protected areas. Noise pollution, originating from both external and internal sources, imposes costs on these areas. It is associated with adverse health effects, while natural sounds contribute to cognitive and emotional improvements as ecosystem services. When it comes to parks, individual visitors hold unique perceptions of soundscapes, which can be shaped by various factors such as their motivations for visiting, personal norms, attitudes towards specific sounds, and expectations. In this study, we utilized linear models and geospatial data to evaluate how visitorsā€™ personal norms and attitudes, the parkā€™s acoustic environment, visitor counts, and the acoustic environment of visitorsā€™ neighborhoods influenced their perception of soundscapes at Muir Woods National Monument. Our findings indicate that visitorsā€™ subjective experiences had a greater impact on their perception of the parkā€™s soundscape compared to purely acoustic factors like sound level of the park itself. Specifically, we found that motivations to hear natural sounds, interference caused by noise, sensitivity to noise, and the sound levels of visitorsā€™ home neighborhoods influenced visitorsā€™ perception of the parkā€™s soundscape. Understanding how personal factors shape visitorsā€™ soundscape perception can assist urban and non-urban park planners in effectively managing visitor experiences and expectations

    Modulation of anabolic and catabolic responses via a porous polymer scaffold manufactured using thermally induced phase separation

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    We describe two studies encompassing the iterative refinement of a polymer-based rhBMP-2 delivery system for bone tissue engineering. Firstly, we compared the boneforming capacity of porous poly(D,L-lactic-co-glycolic acid) (PLGA) scaffolds produced by thermally induced phase separation (TIPS) with non-porous solvent cast poly(D,L-lactic acid) (PDLLA) used previously. Secondly, we examined the potential synergy between rhBMP-2 and local bisphosphonate in the PLGA scaffold system. In vivo ectopic bone formation studies were performed in C57BL6/J mice. Polymer scaffolds containing 0, 5, 10 or 20 Ī¼g rhBMP-2 were inserted into the dorsal musculature. At all rhBMP-2 doses, porous PLGA produced significantly higher bone volume (BV, mm) than the solid PDLLA scaffolds. Next, porous PLGA scaffolds containing 10Ī¼g rhBMP-2 Ā±0.2, or 2Ī¼g zoledronic acid (ZA) were inserted into the hind-limb musculature. Co-delivery of local 10Ī¼g rhBMP-2/2Ī¼g ZA significantly augmented bone formation compared with rhBMP-2 alone (400 % BV increase, p < 0.01). Hydroxyapatite microparticle (HAp) addition (2% w/w) to the 10Ī¼g rhBMP-2/0.2Ī¼g ZA group increased BV (200 %, p < 0.01). We propose that this was due to controlled ZA release of HAp-bound ZA. Consistent with this, elution analyses showed that HAp addition did not alter the rhBMP-2 elution, but delayed ZA release. Moreover, 2 % w/w HAp addition reduced the scaffold's compressive properties, but did not alter ease of surgical handling. In summary, our data show that refinement of the polymer selection and scaffold fabrication can enhance rhBMP-2 induced bone formation in our bone tissue engineering implant, and this can be further optimised by the local co-delivery of ZA/HAp

    Sc2C, a 2D Semiconducting Electride

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    Electrides are exotic materials that typically have electrons present in well-defined lattice sites rather than within atoms. Although all known electrides have an electropositive metal cation adjacent to the electride site, the effect of cation electronegativity on the properties of electrides is not yet known. Here, we examine trivalent metal carbides with varying degrees of electronegativity and experimentally synthesize Sc2C. Our studies identify the material as a two-dimensional (2D) electride, even though Sc is more electronegative than any metal previously found adjacent to an electride site. Further, by exploring Sc2C and Al2C computationally, we find that higher electronegativity of the cation drives greater hybridization between metal and electride orbitals, which opens a band gap in these materials. Sc2C is the first 2D electride semiconductor, and we propose a design rule that cation electronegativity drives the change in its band structure

    Defining an epidemiological landscape that connects movement ecology to pathogen transmission and pace-of-life

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    Pathogen transmission depends on host density, mobility and contact. These components emerge from host and pathogen movements that themselves arise through interactions with the surrounding environment. The environment, the emergent host and pathogen movements, and the subsequent patterns of density, mobility and contact form an ā€˜epidemiological landscapeā€™ connecting the environment to specific locations where transmissions occur. Conventionally, the epidemiological landscape has been described in terms of the geographical coordinates where hosts or pathogens are located. We advocate for an alternative approach that relates those locations to attributes of the local environment. Environmental descriptions can strengthen epidemiological forecasts by allowing for predictions even when local geographical data are not available. Environmental predictions are more accessible than ever thanks to new tools from movement ecology, and we introduce a ā€˜movement-pathogen pace of lifeā€™ heuristic to help identify aspects of movement that have the most influence on spatial epidemiology. By linking pathogen transmission directly to the environment, the epidemiological landscape offers an efficient path for using environmental information to inform models describing when and where transmission will occur
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