A Re-Examination of Racioethnic Imbalance of IS Doctorates: Changing the Face of the IS Classroom

There is an extremely low percentage of minority faculty in the IS field. This global trend is highly conspicuous-- a minority of blacks compared to a majority of white academics in England, a minority of Aborigines compared to a majority of white academics in Australia, a minority of blacks compared to a majority of white academics in Canada, and for the purpose of our study, a minority of Native American, Hispanic American, and African American academics compared to a majority of white academics in the United States. Between 1995-2000, not only do AACSB reports indicate a continuous decline in minority business doctorates, but the accreditation body reports that the IS discipline shows a significant under-representation of minority faculty. In this study, we argue that mentoring under-represented groups in the discipline offers the field a myriad of avenues to change the ¡°face¡± of the classroom and reduce this gap. We examine the absence of racioethnicity and mentoring in the IS field and offer lessons learned from the Ph.D. Project Model for engendering change and mentoring within the IS community. Using data from a six-year period, we discuss diversity issues, lessons learned, and recommendations from mentoring a group of under-represented IS doctoral students

The Impact of Early Identification of Declining Patients: A Quality Improvement Study

This presentation focuses on the prevalence of failure to rescue in healthcare, that we have evidenced in the clinical setting. Proper identification of declining patient health plays a major role in early intervention, resulting in a positive patient outcome. Analyzing common themes in these issues provided a “bigger picture” of the need for proactive patient care.https://scholarworks.moreheadstate.edu/celebration_posters_2023/1034/thumbnail.jp

The Vehicle, Spring 2000

Vol. 41, No. 2 Table of Contents UntitledMatthew A. Thomaspage 4 Fred\u27s PenAutumn Williamspage 5 tomatoesDave Moutraypage 6 AFRICABusinge Roger Godfreypage 7 seeking OutKim Hunterpage 8 Razorblade, Crystal I.Jason Brownpage 9 UntitledMegan Guernseypage 10 CoyoteAutumn Williamspage 11 BaptizedStephanie Carpenterpage 13 BrotherTara Coburnpage 14 My 1984Dave Moutraypage 15 what little boys and girls are made ofKristi Brownfieldpage 17 To GerriMegan Guernseypage 19 JunieJoe Raabpage 20 BeatWes Paytonpage 21 MercyAutumn Williamspage 23 TravelingDenise Fitzerpage 24 UntitledMatthew A. Thomaspage 25 a story of rapeAnnie Whitepage 26 Teddy RhexisPaul Austerpage 30https://thekeep.eiu.edu/vehicle/1074/thumbnail.jp

The Vehicle, Spring 2000

Vol. 41, No. 2 Table of Contents UntitledMatthew A. Thomaspage 4 Fred\u27s PenAutumn Williamspage 5 tomatoesDave Moutraypage 6 AFRICABusinge Roger Godfreypage 7 seeking OutKim Hunterpage 8 Razorblade, Crystal I.Jason Brownpage 9 UntitledMegan Guernseypage 10 CoyoteAutumn Williamspage 11 BaptizedStephanie Carpenterpage 13 BrotherTara Coburnpage 14 My 1984Dave Moutraypage 15 what little boys and girls are made ofKristi Brownfieldpage 17 To GerriMegan Guernseypage 19 JunieJoe Raabpage 20 BeatWes Paytonpage 21 MercyAutumn Williamspage 23 TravelingDenise Fitzerpage 24 UntitledMatthew A. Thomaspage 25 a story of rapeAnnie Whitepage 26 Teddy RhexisPaul Austerpage 30https://thekeep.eiu.edu/vehicle/1074/thumbnail.jp

Movement control tests of the low back; evaluation of the difference between patients with low back pain and healthy controls

<p>Abstract</p> <p>Background</p> <p>To determine whether there is a difference between patients with low back pain and healthy controls in a test battery score for movement control of the lumbar spine.</p> <p>Methods</p> <p>This was a case control study, carried out in five outpatient physiotherapy practices in the German-speaking part of Switzerland. Twelve physiotherapists tested the ability of 210 subjects (108 patients with non-specific low back pain and 102 control subjects without back pain) to control their movements in the lumbar spine using a set of six tests. We observed the number of positive tests out of six (mean, standard deviation and 95% confidence interval of the mean). The significance of the differences between the groups was calculated with Mann-Whitney U test and <it>p </it>was set on <0.05. The effect size (d) between the groups was calculated and d>0.8 was considered a large difference.</p> <p>Results</p> <p>On average, patients with low back pain had 2.21(95%CI 1.94–2.48) positive tests and the healthy controls 0.75 (95%CI 0.55–0.95). The effect size was d = 1.18 (p < 0.001). There was a significant difference between acute and chronic (p < 0.01), as well as between subacute and chronic patient groups (p < 0.03), but not between acute and subacute patient groups (p > 0.7).</p> <p>Conclusion</p> <p>This is the first study demonstrating a significant difference between patients with low back pain and subjects without back pain regarding their ability to actively control the movements of the low back. The effect size between patients with low back pain and healthy controls in movement control is large.</p

RAG-mediated DNA double-strand breaks activate a cell type-specific checkpoint to inhibit pre-B cell receptor signals

DNA double-strand breaks (DSBs) activate a canonical DNA damage response, including highly conserved cell cycle checkpoint pathways that prevent cells with DSBs from progressing through the cell cycle. In developing B cells, pre–B cell receptor (pre–BCR) signals initiate immunoglobulin light (Igl) chain gene assembly, leading to RAG-mediated DNA DSBs. The pre–BCR also promotes cell cycle entry, which could cause aberrant DSB repair and genome instability in pre–B cells. Here, we show that RAG DSBs inhibit pre–BCR signals through the ATM- and NF-κB2–dependent induction of SPIC, a hematopoietic-specific transcriptional repressor. SPIC inhibits expression of the SYK tyrosine kinase and BLNK adaptor, resulting in suppression of pre–BCR signaling. This regulatory circuit prevents the pre–BCR from inducing additional Igl chain gene rearrangements and driving pre–B cells with RAG DSBs into cycle. We propose that pre–B cells toggle between pre–BCR signals and a RAG DSB-dependent checkpoint to maintain genome stability while iteratively assembling Igl chain genes

A cluster randomised controlled trial and evaluation and cost-effectiveness analysis of the Roots of Empathy schools-based programme for improving social and emotional well-being outcomes among 8- to 9-year-olds in Northern Ireland

Background:There is growing consensus regarding the importance of attending to children’s social and emotional well-being. There is now a substantial evidence base demonstrating the links between a child’s early social and emotional development and a range of key longer-term education, social and health outcomes. Universal school-based interventions provide a significant opportunity for early intervention in this area and yet the existing evidence base, particularly in relation to their long-term effects, is limited.Objectives and main outcomes:To determine the effectiveness and cost-effectiveness of Roots of Empathy (ROE), a universal school-based programme that, through attempting to enhance children’s empathy, seeks to achieve the following two main outcomes: improvement in prosocial behaviour and reduction in difficult behaviour.Design:A cluster randomised controlled trial and an economic evaluation. A total of 74 primary schools were randomly assigned to deliver ROE or to join a waiting list control group. Seven schools withdrew post randomisation and a further two withdrew before the immediate post-test time point. Children (n = 1278) were measured pre test and immediately post test, and then for 3 years following the end of the programme. Data were also collected from teachers and parents.Setting and participants:The intervention schools delivered ROE to their Year 5 children (aged 8–9 years) as a whole class.Intervention:ROE is delivered on a whole-class basis for one academic year (October–June). It consists of 27 lessons based around the monthly visit from a baby and parent who are usually recruited from the local community. Children learn about the baby’s growth and development and are encouraged to generalise from this to develop empathy towards others.Results:Although it was developed in Canada, the programme was very well received by schools, parents and children, and it was delivered effectively with high fidelity. ROE was also found to be effective in achieving small improvements in children’s prosocial behaviour (Hedges’ g = 0.20; p = 0.045) and reductions in their difficult behaviour (Hedges’ g = –0.16; p = 0.060) immediately post test. Although the gains in prosocial behaviour were not sustained after the immediately post-test time point, there was some tentative evidence that the effects associated with reductions in difficult behaviour may have remained up to 36 months from the end of the programme. These positive effects of ROE on children’s behaviour were not found to be associated with improvements in empathy or other social and emotional skills (such as emotional recognition and emotional regulation), on which the trial found no evidence of ROE having an effect. The study also found that ROE was likely to be cost-effective in line with national guidelines.Conclusions:These findings are consistent with those of other evaluations of ROE and suggest that it is an effective and cost-effective programme that can be delivered appropriately and effectively in regions such as Northern Ireland. A number of issues for further consideration are raised regarding opportunities to enhance the role of parents; how a time-limited programme such as ROE can form part of a wider and progressive curriculum in schools to build on and sustain children’s social and emotional development; and the need to develop a better theory of change for how ROE works.Trial registration:Current Controlled Trials ISRCTN07540423.Funding:This project was funded by the National Institute for Health Research (NIHR) Public Health Research programme and will be published in full in Public Health Research; Vol. 6, No. 4. See the NIHR Journals Library website for further project information

Parallel Odor Processing by Two Anatomically Distinct Olfactory Bulb Target Structures

The olfactory cortex encompasses several anatomically distinct regions each hypothesized to provide differential representation and processing of specific odors. Studies exploring whether or not the diversity of olfactory bulb input to olfactory cortices has functional meaning, however, are lacking. Here we tested whether two anatomically major olfactory cortical structures, the olfactory tubercle (OT) and piriform cortex (PCX), differ in their neural representation and processing dynamics of a small set of diverse odors by performing in vivo extracellular recordings from the OT and PCX of anesthetized mice. We found a wealth of similarities between structures, including odor-evoked response magnitudes, breadth of odor tuning, and odor-evoked firing latencies. In contrast, only few differences between structures were found, including spontaneous activity rates and odor signal-to-noise ratios. These results suggest that despite major anatomical differences in innervation by olfactory bulb mitral/tufted cells, the basic features of odor representation and processing, at least within this limited odor set, are similar within the OT and PCX. We predict that the olfactory code follows a distributed processing stream in transmitting behaviorally and perceptually-relevant information from low-level stations