179 research outputs found

    Rapid Assessment of Vietnam\u27s Labor Inspection System

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    [Excerpt] In July 2010, a team from the U.S. Department of Labor (USDOL) visited Vietnam to conduct an assessment of the Ministry of Labor, War Invalids & Social Affairs’ (MOLISA) labor inspection system. This effort was requested by the SIIR project (funded by USAID) as part of its aim of identifying MOLISA’s needs and providing assistance, per MOLISA’s request. The Assessment focuses on: 1) assessing facts related to the labor inspection system; and 2) providing initial recommendations for improving the system. Part I discusses MOLISA’s history, legal and regulatory framework, structure and organization, Department of Labor Inspections (including workforce, forms and data collection, and IPZ). Part II discusses issues and presents recommendations related to data collection, labor inspector training, inspectorate staffing levels, educational outreach, research and networking, systems of continuous improvement, and coordination with international and private buyers

    The Westminster contradiction : sanctuary privileges during the Ricardian usurpation

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    Multi-metal electrohydrodynamic redox 3d printing at the submicron scale: Microstructure – geometrical gradients – chemical gradients and the resulting mechanical properties

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    An extensive range of metals can be dissolved and re-deposited in liquid solvents using electrochemistry. We harness this concept for additive manufacturing, demonstrating the focused electrohydrodynamic ejection of metal ions dissolved from sacrificial anodes and their subsequent reduction to elemental metals on the substrate. This technique, termed electrohydrodynamic redox printing (EHD-RP), enables the direct, ink-free fabrication of polycrystalline multi-metal 3D structures without the need for post-print processing. On- the-fly switching and mixing of two or more metals printed from a single multichannel nozzle facilitates a chemical feature size of \u3c400 nm with a spatial resolution of 250 nm at printing speeds of up to 10 voxels per second. The additive control of the chemical architecture of materials provided by EHD-RP unlocks the synthesis of 3D bi-metal structures with programmed local properties and opens new avenues for the direct fabrication of chemically architected materials and devices. Mechanical properties can be locally controlled by alloying, dealloying (resulting in controlled porosity) and grain-size tuning via process control. The properties of EHD-RP are put into perspective by comparing with the most prominent current technologies for metal 3D printing at the nanoscale (Fig. 1). Please click Additional Files below to see the full abstract

    Pharmacotherapy for treatment-resistant schizophrenia

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    Schizophrenia is a disabling mental illness with a lifetime prevalence of 0.7% worldwide and significant, often devastating, consequences on social and occupational functioning. A range of antipsychotic medications are available; however, suboptimal therapeutic response in terms of psychotic symptoms is common and affects up to one-third of people with schizophrenia. Negative symptoms are generally less amenable to treatment. Because of the consequences of inadequate symptom control, effective treatment strategies are required for people with treatment-resistant schizophrenia. Clozapine has been shown to be more effective than other antipsychotics in treatment-resistant populations in several studies; however, the occurrence of adverse effects, some of which are potentially life-threatening, are important limitations. In addition to those who are intolerant to clozapine, only 30% to 50% experience clinically significant symptom improvement. This review describes the recent evidence for treatment strategies for people not responding to nonclozapine antipsychotic agents and people not responding or only partially responding to clozapine

    High temperature indentation creep and nanoindentation testing of superalloys and TiAl alloys

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    Measuring of the high temperature mechanical behaviour of materials by local testing has become a key task in the field of nanomechanics. However, gaining access to the application temperature of many metallic high temperature materials, which is in the range of 600°C - 1100°C, is quite difficult. In addition, creep parameters can only be determined by long time measurements, where drift influences become a severe challenge. Here we present a new approach of indentation creep testing with a flat punch indenter. For this, a thermo mechanical analyzer with very precise temperature control is used, which allows testing at temperatures up to 1200°C. A flat punch indenter with a diameter of around 10 µm allows for example local investigations of the creep properties on the dendritic scale of superalloys. This approach is also interesting to study the creep properties along the gradient of diffusion couples. Here, first test measurements on superalloys and other materials are presented and discussed. For comparison also high temperature nanoindentation measurements will be shown. Such measurements have been conducted on a multiphase titanium aluminide alloy from room temperature up to 600°C. The results show, that the hardness of the (β0+ω0)-composite phase is the highest among all phases and remains constant up to the service temperature. Both approaches of high temperature testing are compared and the prospect of these methods will be discussed

    Phase II trial of murine monoclonal antibody D612 combined with recombinant human monocyte colony-stimulating factor (rhM-CSF) in patients with metastatic gastrointestinal cancer

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    In a Phase II study, 14 patients with metastatic gastrointestinal cancer received the mAb D612 (40 mg/m2, days 4, 7, and 11) in combination with recombinant human monocyte colony-stimulating factor [(rhM-CSF) 80 ug/kg/days 1-14]. The combined treatment was well tolerated and resulted in characteristic biological activity associated with each of the agents. Thus, 10 of 14 patients experienced D612-associated secretory diarrhea, which responded to the prostaglandin inhibitor Indomethacin in 5 of 7 patients. rhM-CSF therapy was associated with peripheral mono- cytosis (peak absolute monocyte count, 1444 ±394/mm3) and thrombocytopenia (nadir count, 78 ±10/nim \u27). Monocyte surface marker analysis revealed a high baseline expression of CD Id \u27 cells in our patient popu lation with an additional increase with rhM-CSF therapy. We observed a correlation between the degree of thrombocytopenia and the pretreatment CD16+ monocyte count. Of the plasma cytokines assayed, serum Neopterin demonstrated the most consistent increase during rhM-CSF therapy. There was a significant difference in the half-life of the first and last dose of D612 (3S.8 ±2 versus 27 ±2.9 h; P \u3c 0.05). Eleven of fourteen patients developed low-moderate levels of anti-D612 antibody. Despite the ob served biological activity of both rhM-CSF and D612 and the previously described in vitro synergy, no clinical antitumor responses were observed in this Phase II study

    What is the health insurance marketplace?

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    The Oklahoma Cooperative Extension Service periodically issues revisions to its publications. The most current edition is made available. For access to an earlier edition, if available for this title, please contact the Oklahoma State University Library Archives by email at [email protected] or by phone at 405-744-6311

    Herbicide Evaluation in Arkansas Rice, 1998

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    Weed control is economically important for production of rice, a major crop in Arkansas. These findings summarize efforts of the team of Arkansas scientists working on weed control strategies for rice during 1998. Various technologies were evaluated in field studies involving the major weed problems and rice production systems used in the state. Results from these studies will add to the arsenal of weed control options for producers. The preliminary results reported here generally warrant further testing for more advanced findings and for the labeling of new technologies and, finally, are the basis for updating safe, effective, and economical recommendations to Arkansas rice producers
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