Cepheid and Tip of the Red Giant Branch Distances To the Dwarf Irregular Galaxy IC10

We present color-magnitude diagrams and luminosity functions of stars in the nearby galaxy IC 10, based on VI CCD photometry acquired with the COSMIC prime-focus camera on the Palomar 5m telescope. The apparent I-band luminosity function of stars in the halo of IC 10 shows an identifiable rise at I~21.7 mag. This is interpreted as being the tip of the red giant branch (TRGB) at M_V~-4 mag. Since IC 10 is at a very low Galactic latitude, its foreground extinction is expected to be high and the uncertainty associated with that correction is the largest contributor to the error associated with its distance determination. Multi-wavelength observations of Cepheid variable stars in IC 10 give a Population I distance modulus of 24.1 +- 0.2 mag, which corresponds to a linear distance of 660 +- 66 kpc for a total line-of-sight reddening of E(B-V) = 1.16 +- 0.08 mag, derived self-consistently from the Cepheid data alone. Applying this Population I reddening to the Population II halo stars gives a TRGB distance modulus of 23.5 +- 0.2 mag, corresponding to 500 +- 50 kpc. We consider this to be a lower limit on the TRGB distance. Reconciling the Cepheid and TRGB distances would require that the reddening to the halo is $\Delta$E(B-V) = 0.31 mag lower than that into the main body of the galaxy. This then suggests that the Galactic extinction in the direction of IC10 is (B-V) ~ 0.85

The Association Between Frequency of Alcohol Drinking and Neurobehaviors

Drinking culture is very prevalent in colleges across the United States. The effects of binge drinking and mindfulness habits/overall mood of students in college and their correlation have yet to be researched. An anonymous online survey was administered through GroupMe and iMessage chats. The survey included basic demographic questions of each participant and questions on their drinking, diet, resilience, exercise patterns, and overall mood. Pearson’s Correlation Analysis was utilized using SPSS version 28.0. Results suggest that there is a relationship between alcohol consumption, mental distress state, and mindfulness among college students. With college students, reducing alcohol consumption may modulate neurobehaviors.https://orb.binghamton.edu/research_days_posters_2024/1066/thumbnail.jp

The Longer-Term Effects of a Single Bupivacaine Exposure on the Mechanical Properties of Native Cartilage Explants.

OBJECTIVE: The purpose of this study was to determine the in vitro effects of a single exposure of bupivacaine on the mechanical properties of bovine cartilage explants at 3 weeks. DESIGN: Femoral condyle articular cartilage explants were aseptically harvested from juvenile bovine stifle joints before being exposed to chondrogenic medium containing 0.50% (wt/vol) bupivacaine, 0.25% (wt/vol) bupivacaine, or no medication (control) for 1 hour. Explants were then washed and maintained in culture in vitro for 3 weeks before testing. Cell viability, tensile and compressive mechanical properties, histological properties, and biochemical properties were then assessed. RESULTS: Explants exhibited a dose-dependent decrease in mean tensile Youngs modulus with increasing bupivacaine concentration (9.86 MPa in the controls, 6.48 MPa in the 0.25% bupivacaine group [P = 0.048], and 4.72 MPa in the 0.50% bupivacaine group [P = 0.005]). Consistent with these results, collagen content and collagen crosslinking decreased with bupivacaine exposure as measured by mass spectrometry. Compressive properties of the explants were unaffected by bupivacaine exposure. Explants also exhibited a trend toward dose-dependent decreases in viability (51.2% for the controls, 47.3% for the 0.25% bupivacaine-exposed group, and 37.0% for the 0.50% bupivacaine-exposed group [P = 0.072]). CONCLUSIONS: Three weeks after 1-hour bupivacaine exposure, the tensile properties of bovine cartilage explants were significantly decreased, while the compressive properties remained unaffected. These decreases in tensile properties corresponded with reductions in collagen content and crosslinking of collagen fibers. Physicians should be judicious regarding the intra-articular administration of bupivacaine in native joints

On Silicon Group Elements Ejected by Supernovae Type Ia

There is compelling evidence that the peak brightness of a Type Ia supernova is affected by the electron fraction Ye at the time of the explosion. The electron fraction is set by the aboriginal composition of the white dwarf and the reactions that occur during the pre explosive convective burning. To date, determining the makeup of the white dwarf progenitor has relied on indirect proxies, such as the average metallicity of the host stellar population. In this paper, we present analytical calculations supporting the idea that the electron fraction of the progenitor systematically influences the nucleosynthesis of silicon group ejecta in Type Ia supernovae. In particular, we suggest the abundances generated in quasi nuclear statistical equilibrium are preserved during the subsequent freezeout. This allows one to potential recovery of Ye at explosion from the abundances recovered from an observed spectra. We show that measurement of 28Si, 32S, 40Ca, and 54Fe abundances can be used to construct Ye in the silicon rich regions of the supernovae. If these four abundances are determined exactly, they are sufficient to recover Ye to 6 percent. This is because these isotopes dominate the composition of silicon-rich material and iron rich material in quasi nuclear statistical equilibrium. Analytical analysis shows that the 28Si abundance is insensitive to Ye, the 32S abundance has a nearly linear trend with Ye, and the 40Ca abundance has a nearly quadratic trend with Ye. We verify these trends with post-processing of 1D models and show that these trends are reflected in model synthetic spectra.Comment: Submitted to the Ap

Procesos comunicacionales y representaciones sociales que tienen los jóvenes sobre la música de gaitas y su influencia en la tradición musical desde San Jacinto, Bolívar /

La música de gaitas es un género autóctono colombiano que toma su nombre del instrumento principal “la gaita”, que tiene dos referencias la gaita hembra con cinco orificios y gaita macho con dos. El músico que lo manipula siempre acompaña el ritmo con una maraca. Otros instrumentos que acompañan el género son los tambores en sus diferentes presentaciones: Tambor alegre; el tambor llamador que lleva el ritmo del conjunto; y la tambora, de mayor tamaño. Este género musical es propio de la región Caribe Colombiana, principalmente en los departamentos de Bolívar, Sucre y Córdoba. Enrique Sánchez Gutiérrez, un sociólogo del ministerio colombiano de cultura, en un informe para la UNESCO sobre la situación del PCI Afrodescendiente en Colombia confirmó que “Los gaiteros interpretan ritmos como cumbias, bullerengues, puyas, porros y sones”. “Los Gaiteros de San Jacinto” es el grupo más reconocido por su tradición musical que ha venido pasando de padres a hijos. Un CD suyo “Fuego en la sangre” grabado por el Smithsonian Folkway Recordings, ganó un premio Grammy latino”, puntualiza Sánchez. Este proyecto nace con el fin de aplicar las ciencias de la comunicación para trabajar en las problemáticas que aquejan el ámbito cultural.Incluye bibliografía, anexo

Mechanical Evaluation of Commercially Available Fibrin Sealants for Cartilage Repair.

OBJECTIVE: Fibrin sealants are routinely used for intra-articular surgical fixation of cartilage fragments and implants. However, the mechanical properties of fibrin sealants in the context of cartilage repair are unknown. The purpose of this study was to characterize the adhesive and frictional properties of fibrin sealants using an ex vivo model. DESIGN: Native bovine cartilage-bone composites were assembled with a single application of Tisseel or Vistaseal. Composites were tested in tension and lap shear. In addition, the coefficient of friction (COF) was measured in a native cartilage annulus model alone and with minced cartilage. Finally, the effect of a double application of fibrin sealant was evaluated. RESULTS: There were no significant differences in tensile modulus, ultimate tensile strength (UTS), shear modulus, or ultimate shear strength (USS) between the 2 fibrin sealants. Both fibrin sealants demonstrated a UTS and USS of <8 and <30 kPa, respectively. There were no differences in COF between the sealants when tested alone or with minced cartilage. A double application of fibrin sealant did not alter the mechanical properties compared with a single application of fibrin sealant. CONCLUSIONS: Fibrin sealant adhesive properties are not affected by the sealant type studied or the number of applications in a bovine cartilage-bone model. Fibrin sealant tribological properties are not affected by sealant type or the addition of minced cartilage. The adhesive properties of Tisseel and Vistaseal were less than those desired for the in vivo fixation of cartilage repair implants. These findings motivate the development of an improved cartilage-specific adhesive for cartilage repair applications

A Collaborative Approach: Assessing the Impact of Multi-Grade Classrooms

Catholic schools in the United States are faced with the looming challenge of declining enrollments. One possible strategy for dealing with this problem is to institute multi-grade classrooms where students from two or more grades are combined in one classroom with one instructor. In this article, the authors examined one urban Catholic school’s successful transition to multi-grade classrooms when student enrollment dropped dramatically. The transition to multi-grade classrooms did not have a significant impact on student outcomes as measured by absences, tardiness, or academic performance though other social-emotional and developmental benefits were perceived. For example, the students were more likely to nurture other students and be nurtured by them; assume shared responsibility and leadership in the classroom and at home; were involved in fewer disciplinary incidents; and were more respectful of their classmates. The researchers offer lessons learned about the transition for other Catholic school leaders who may be considering such a change

Gene Dosage Effects of the Imprinted Delta-Like Homologue 1 (Dlk1/Pref1) in Development: Implications for the Evolution of Imprinting

Genomic imprinting is a normal process that causes genes to be expressed according to parental origin. The selective advantage conferred by imprinting is not understood but is hypothesised to act on dosage-critical genes. Here, we report a unique model in which the consequences of a single, double, and triple dosage of the imprinted Dlk1/Pref1, normally repressed on the maternally inherited chromosome, can be assessed in the growing embryo. BAC-transgenic mice were generated that over-express Dlk1 from endogenous regulators at all sites of embryonic activity. Triple dosage causes lethality associated with major organ abnormalities. Embryos expressing a double dose of Dlk1, recapitulating loss of imprinting, are growth enhanced but fail to thrive in early life, despite the early growth advantage. Thus, any benefit conferred by increased embryonic size is offset by postnatal lethality. We propose a negative correlation between gene dosage and survival that fixes an upper limit on growth promotion by Dlk1, and we hypothesize that trade-off between growth and lethality might have driven imprinting at this locus

Adding web-based support to exercise referral schemes improves symptoms of depression in people with elevated depressive symptoms:A secondary analysis of the e-coachER randomised controlled trial

Background: Exercise referral schemes (ERS) reduce depression but the additional effect on mental health from web-based behavioural support is unknown. The e-coachER trial reported no effect of augmenting usual ERS with theory-driven web-based behavioural support on moderate to vigorous physical activity (MVPA) at 12 months for patients with chronic physical and mental health conditions. The present study reports the effects of the e-coachER intervention on depression, anxiety and MVPA only among participants with elevated depressive symptoms and investigates whether these were mediated by changes in MVPA and hypothesised cognitive and behavioural processes. Methods: Of the original 450 adults recruited into the e-coachER trial, 205 had at least mild depression, based on the Hospital Anxiety and Depression Scale (HADS), and were included in the present analysis. Data collected included the HADS, accelerometer measured and self-reported MVPA and survey process measures on physical activity action planning, self-monitoring and goal reviewing, and perceived importance, confidence, competence, autonomy and support. Linear mixed models were used to compare groups for change in depression and anxiety at 4 and 12 months using intention-to-treat complete case analysis, controlling for baseline. We also examined whether changes in physical activity and process variables at 4 months mediated changes in depression and anxiety at 12 months. Results: Of the 205 participants, 138 (67%) provided follow-up data at four months and 126 (61%) at 12 months. For those that provided follow-up data, those randomised to e-coachER reported improved levels of depression (−1.36, 95% CI: −2.55 to −0.18) but not anxiety, or MVPA, compared with controls at four months. No differences were observed at 12 months for depression, anxiety or MVPA. Intervention effects on accelerometer-measured or self-reported MVPA did not mediate improvements in depression or anxiety. However, intervention effects on confidence, competence and self-monitoring at four months significantly mediated the reduction in depression scores at four months. Intervention effects on competence and self-monitoring at four months also significantly mediated improvements in anxiety scores at four months. Interpretation: Adding web-based support to usual ERS leads to reductions in depression but not anxiety at four months. Changes in depression and anxiety were influenced by changing people's motivational regulations toward physical activity. The benefit of adding web-based support to usual ERS on mental health appears to be from increasing a sense of confidence, competence and self-monitoring rather than from increasing physical activity in people with elevated depression. ERS should focus more on strengthening motivational regulations than just doing more exercise. Trial registration: ISRCTN15644451.</p