3,673 research outputs found

    A Maxwell-vector p-wave holographic superconductor in a particular background AdS black hole metric

    Full text link
    We study the p-wave holographic superconductor for AdS black holes with planar event horizon topology for a particular Lovelock gravity, in which the action is characterized by a self-interacting scalar field nonminimally coupled to the gravity theory which is labeled by an integer kk. As the Lovelock theory of gravity is the most general metric theory of gravity based on the fundamental assumptions of general relativity, it is a desirable theory to describe the higher dimensional spacetime geometry. The present work is devoted to studying the properties of the p-wave holographic superconductor by including a Maxwell field which nonminimally couples to a complex vector field in a higher dimensional background metric. In the probe limit, we find that the critical temperature decreases with the increase of the index kk of the background black hole metric, which shows that a larger kk makes it harder for the condensation to form. We also observe that the index kk affects the conductivity and the gap frequency of the holographic superconductors.Comment: 14 pages, 6 figure

    Hydrogen Generation from Al-NiCl2/NaBH4 Mixture Affected by Lanthanum Metal

    Get PDF
    The effect of La on Al/NaBH4 hydrolysis was elaborated in the present paper. Hydrogen generation amount increases but hydrogen generation rate decreases with La content increasing. There is an optimized composition that Al-15 wt% La-5 wt% NiCl2/NaBH4 mixture (Al-15 wt% La-5 wt% NiCl2/NaBH4 weight ratio, 1 : 3) has 126 mL g−1 min−1 maximum hydrogen generation rate and 1764 mL g−1 hydrogen generation amount within 60 min. The efficiency is 88%. Combined with NiCl2, La has great effect on NaBH4 hydrolysis but has little effect on Al hydrolysis. Increasing La content is helpful to decrease the particle size of Al-La-NiCl2 in the milling process, which induces that the hydrolysis byproduct Ni2B is highly distributed into Al(OH)3 and the catalytic reactivity of Ni2B/Al(OH)3 is increased therefore. But hydrolysis byproduct La(OH)3 deposits on Al surface and leads to some side effect. The Al-La-NiCl2/NaBH4 mixture has good stability in low temperature and its hydrolytic performance can be improved with increasing global temperature. Therefore, the mixture has good safety and can be applied as on board hydrogen generation material

    Aloin promotes cell apoptosis by targeting HMGB1-TLR4-ERK axis in human melanoma cells

    Get PDF
    Aloin (ALO) is the major anthraquinone glycoside purified from the Aloe species. It is well known for its anti-tumor effects. However, the protective effects of ALO in melanoma cancer and underlying molecular mechanism remain unclear. High-mobility group protein B1 (HMGB1) is an intracellular protein, which has closely association with cell survival, proliferation and metastasis in various cancers. In this study, we explored the effect of ALO on cell survival and apoptosis by targeting HMGB1 signal pathway. We confirmed that ALO exerts a strong effect on promoting cell apoptosis of melanoma cells in vitro. Furthermore, HMGB1 release was significantly inhibited in melanoma cancer cells treated with ALO. Knockdown of HMGB1 could enhance melanoma cell death that is induced by ALO treatment. Moreover, HMGB1 facilitated ALO mediated melanoma cell apoptosis by binding to its receptor, Toll-like receptor 4 and activating extracellular regulated protein kinases (ERK) signal pathway. Altogether, our study demonstrated that ALO plays an important role in promoting apoptosis of melanoma cells by inhibiting HMGB1 release and activation of downstream ERK signal pathway

    POMP: Probability-driven Meta-graph Prompter for LLMs in Low-resource Unsupervised Neural Machine Translation

    Full text link
    Low-resource languages (LRLs) face challenges in supervised neural machine translation due to limited parallel data, prompting research into unsupervised methods. Unsupervised neural machine translation (UNMT) methods, including back-translation, transfer learning, and pivot-based translation, offer practical solutions for LRL translation, but they are hindered by issues like synthetic data noise, language bias, and error propagation, which can potentially be mitigated by Large Language Models (LLMs). LLMs have advanced NMT with in-context learning (ICL) and supervised fine-tuning methods, but insufficient training data results in poor performance in LRLs. We argue that LLMs can mitigate the linguistic noise with auxiliary languages to improve translations in LRLs. In this paper, we propose Probability-driven Meta-graph Prompter (POMP), a novel approach employing a dynamic, sampling-based graph of multiple auxiliary languages to enhance LLMs' translation capabilities for LRLs. POMP involves constructing a directed acyclic meta-graph for each source language, from which we dynamically sample multiple paths to prompt LLMs to mitigate the linguistic noise and improve translations during training. We use the BLEURT metric to evaluate the translations and back-propagate rewards, estimated by scores, to update the probabilities of auxiliary languages in the paths. Our experiments show significant improvements in the translation quality of three LRLs, demonstrating the effectiveness of our approach

    Strength-dependent Transition of Graphite Under Shock Condition Resolved by First Principles

    Full text link
    The shock strength dependent formation of diamond represents one of the most intriguing questions in graphite research. Using ab initio DFT-trained carbon GNN model, we observe a strength-dependent graphite transition under shock. The poor sliding caused by scarce sliding time under high-strength shock forms hexagonal diamond with an orientation of (001)G//(100)HD+[010]G//[010]HD; under low-strength shock, cubic diamond forms after enough sliding time, unveiling the strength-dependent graphite transition. We provide computational evidence of the strength-dependent graphite transition from first principles, clarifying the long-term shock-induced hexagonal formation and structural strength-dependent trend source

    Cavernous Transformation of the Portal Vein Might Increase the Risk of Liver Abscess

    Get PDF
    Cavernous transformation of the portal vein (CTPV) is not quite common in adults, and cases with CTPV and acute liver abscess are lacking. We report a patient with CTPV inducing extrahepatic and intrahepatic obstruction, finally leading to acute liver abscess due to bile duct infection. We aim to find out the possible relationship between CTPV and acute liver abscess. A 45-year-old female patient was admitted to our hospital for recurrent upper abdominal pain and distension for one year, aggravated with fever for three years. A diagnosis of CTPV and liver abscess was made by 16-slice computed tomography. Effective antibiotics and drainage were used for this patients, and she was eventually cured. When treating patients with CTPV, extrahepatic and intrahepatic obstruction, one should be aware of the presence of acute liver abscess, and empirical antibiotics might be valuable

    Study of Characteristic and Period of Communication and Electronics Industry in Chinese Securities Market

    Get PDF
    Purpose: This study aims to analyze the characteristics of communication and electronics industry in Chinese stock market and calculate the average periods of it. Design/methodology/approach: We use R/S analysis method to study the characteristics of communication and electronics industry in Chinese stock market, and use Matlab software and Eviews software to calculate some representative exponents of this industry. Findings: The results show that the probability distribution of the communication and electronics industry in the Chinese stock market is nearly non-normal distribution, but a partial distribution, showing a peak, thick tail, migraine and other features. Hurst exponent calculated shows that the communication and electronics industry in the Chinese stock market has obvious fractal characteristics, and does not follow a random walk assumption, but follows persistent trend. The average big circulation period is about 400 days; the average small circulation period is about 200 days. Research limitations/implications: We use R/S analysis method to study the characteristics including periods and venture.of communication and electronics industry in Chinese stock market. Practical implications: The average periods and related venture can give investors properly suggestions. Originality/Value: We use R/S analysis method and Matlab software and Eviews software to analyze the characteristics of communication and electronics industry in Chinese stock market which has barely been studied. The results unfold the characteristics of this industry and can give investors properly suggestions as well.Key words: Stock market; Fractal; R/S analysis; Hurst exponent; Periods; Communication and electronic

    Genome-wide gene-based association study

    Get PDF
    Genome-wide association studies, which analyzes hundreds of thousands of single-nucleotide polymorphisms to identify disease susceptibility genes, are challenging because the work involves intensive computation and complex modeling. We propose a two-stage genome-wide association scanning procedure, consisting of a single-locus association scan for the first stage and a gene-based association scan for the second stage. Marginal effects of single-nucleotide polymorphisms are examined by using the exact Armitage trend test or logistic regression, and gene effects are examined by using a p-value combination method. Compared with some existing single-locus and multilocus methods, the proposed method has the following merits: 1) convenient for definition of biologically meaningful regions, 2) powerful for detection of minor-effect genes, 3) helpful for alleviation of a multiple-testing problem, and 4) convenient for result interpretation. The method was applied to study Genetic Analysis Workshop 16 Problem 1 rheumatoid arthritis data, and strong association signals were found. The results show that the human major histocompatibility complex region is the most important genomic region associated with rheumatoid arthritis. Moreover, previously reported genes including PTPN22, C5, and IL2RB were confirmed; novel genes including HLA-DRA, BTNL2, C6orf10, NOTCH4, TAP2, and TNXB were identified by our analysis
    corecore