22,306 research outputs found

    Spiritual flourishing in the words of the child: Final report for young people: A Faith in the Nexus study 2023

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    Since the pandemic, there has been widespread increased concern about children's spiritual well-being. [The pandemic] is a once in a generation opportunity to transform the wider education system around the child so that wellbeing is truly at the heart of the learning environment in schools. (Barnardo’s, 2020) [A] challenge faced by the child Jesus set in our midst is one of health and safety and especially mental, emotional, and spiritual health...COVID has revealed a tidal wave of mental health pressures on the young which has been building for decades. (Bishop Steven, Oxford Diocese) We know from previous NICER research , conducted before the pandemic that there is a need to pay attention to and nurture the spirituality of children for them to flourish. We also know that many adults have limited awareness of the importance of this nurture and do not fully appreciate what children need to flourish spiritually. Research has shown that Faith communities have the potential to be a vital source of a sense of belonging and support for the spiritual nurture of children and adults. We identified a need to research children's understanding of what contributes to their spiritual well-being within the church school community context

    Spiritual flourishing in the words of the child: A Faith in the Nexus study 2023

    Get PDF
    Since the pandemic, there has been widespread increased concern about children's spiritual well-being. [The pandemic] is a once in a generation opportunity to transform the wider education system around the child so that wellbeing is truly at the heart of the learning environment in schools. (Barnardo’s, 2020) [A] challenge faced by the child Jesus set in our midst is one of health and safety and especially mental, emotional, and spiritual health...COVID has revealed a tidal wave of mental health pressures on the young which has been building for decades. (Bishop Steven, Oxford Diocese) We know from previous NICER research , conducted before the pandemic that there is a need to pay attention to and nurture the spirituality of children for them to flourish. We also know that many adults have limited awareness of the importance of this nurture and do not fully appreciate what children need to flourish spiritually. Research has shown that Faith communities have the potential to be a vital source of a sense of belonging and support for the spiritual nurture of children and adults. We identified a need to research children's understanding of what contributes to their spiritual well-being within the church school community context

    Structural and functional conservation of the human homolog of the Schizosaccharomyces pombe rad2 gene, which is required for chromosome segregation and recovery from DNA damage

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    The rad2 mutant of Schizosaccharomyces pombe is sensitive to UV irradiation and deficient in the repair of UV damage. In addition, it has a very high degree of chromosome loss and/or nondisjunction. We have cloned the rad2 gene and have shown it to be a member of the Saccharomyces cerevisiae RAD2/S. pombe rad13/human XPG family. Using degenerate PCR, we have cloned the human homolog of the rad2 gene. Human cDNA has 55% amino acid sequence identity to the rad2 gene and is able to complement the UV sensitivity of the rad2 null mutant. We have thus isolated a novel human gene which is likely to be involved both in controlling the fidelity of chromosome segregation and in the repair of UV-induced DNA damage. Its involvement in two fundamental processes for maintaining chromosomal integrity suggests that it is likely to be an important component of cancer avoidance mechanisms

    Finite size effects in perturbed boundary conformal field theories

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    We discuss the finite-size properties of a simple integrable quantum field theory in 1+1 dimensions with non-trivial boundary conditions. Novel off-critical identities between cylinder partition functions of models with differing boundary conditions are derived.Comment: 7 pages, 11 figures, JHEP proceedings style. Uses epsfig, amssymb. Talk given at the conference `Nonperturbative Quantum Effects 2000', Pari

    Non-nequilibrium model on Apollonian networks

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    We investigate the Majority-Vote Model with two states (1,+1-1,+1) and a noise qq on Apollonian networks. The main result found here is the presence of the phase transition as a function of the noise parameter qq. We also studies de effect of redirecting a fraction pp of the links of the network. By means of Monte Carlo simulations, we obtained the exponent ratio γ/ν\gamma/\nu, β/ν\beta/\nu, and 1/ν1/\nu for several values of rewiring probability pp. The critical noise was determined qcq_{c} and UU^{*} also was calculated. The effective dimensionality of the system was observed to be independent on pp, and the value Deff1.0D_{eff} \approx1.0 is observed for these networks. Previous results on the Ising model in Apollonian Networks have reported no presence of a phase transition. Therefore, the results present here demonstrate that the Majority-Vote Model belongs to a different universality class as the equilibrium Ising Model on Apollonian Network.Comment: 5 pages, 5 figure

    Nse2, a component of the Smc5-6 complex, is a SUMO ligase required for the response to DNA damage

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    The Schizosaccharomyces pombe SMC proteins Rad18 (Smc6) and Spr18 (Smc5) exist in a high-M(r) complex which also contains the non-SMC proteins Nse1, Nse2, Nse3, and Rad62. The Smc5-6 complex, which is essential for viability, is required for several aspects of DNA metabolism, including recombinational repair and maintenance of the DNA damage checkpoint. We have characterized Nse2 and show here that it is a SUMO ligase. Smc6 (Rad18) and Nse3, but not Smc5 (Spr18) or Nse1, are sumoylated in vitro in an Nse2-dependent manner, and Nse2 is itself autosumoylated, predominantly on the C-terminal part of the protein. Mutations of C195 and H197 in the Nse2 RING-finger-like motif abolish Nse2-dependent sumoylation. nse2.SA mutant cells, in which nse2.C195S-H197A is integrated as the sole copy of nse2, are viable, whereas the deletion of nse2 is lethal. Smc6 (Rad18) is sumoylated in vivo: the sumoylation level is increased upon exposure to DNA damage and is drastically reduced in the nse2.SA strain. Since nse2.SA cells are sensitive to DNA-damaging agents and to exposure to hydroxyurea, this implicates the Nse2-dependent sumoylation activity in DNA damage responses but not in the essential function of the Smc5-6 complex

    Pre-Big Bang Scenario on Self-T-Dual Bouncing Branes

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    We consider a new class of 5-dimensional dilatonic actions which are invariant under T-duality transformations along three compact coordinates, provided that an appropriate potential is chosen. We show that the invariance remains when we add a boundary term corresponding to a moving 3-brane, and we study the effects of the T-duality symmetry on the brane cosmological equations. We find that T-duality transformations in the bulk induce scale factor duality on the brane, together with a change of sign of the pressure of the brane cosmological matter. However, in a remarkable analogy with the Pre-Big Bang scenario, the cosmological equations are unchanged. Finally, we propose a model where the dual phases are connected through a scattering of the brane induced by an effective potential. We show how this model can realise a smooth, non-singular transition between a pre-Big Bang superinflationary Universe and a post-Big Bang accelerating Universe.Comment: 18 pages, minor typos corrected, Sec. 2 expanded with more details on the self-T-dual background, Sec.4 and 5 revised accordingly. Version to appear on JCA
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